Shared Flashcard Set

Details

Pharm-Protein Synth Inhibitors
na
11
Pharmacology
Post-Graduate
08/06/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Drug of choice for legionellosis
Definition
Azythromycin
Term
Chlamydial urogenital infections during pregnancy (tetracyclines are contraindicated
Definition
Macrolides (Erythromycin,Azithromycin), Amoxacillin
Term
Most common side effect of Macrolides?
Definition
GIT distress
Term
Describe mechanism of resstance to macrolides
Definition
methylase enzyme adds a meythl group to ribosomal binding site
Term
Mechnism of Action of Clindamycin
Definition
Like macrolids, inhibits transfer of peptidyl tRNA from the A site to the P site
Term
Therapeutic use of clindamyci?
Definition
Baceroides fragilis (anaerobic)
Term
ADEs of clindamycin?
Definition
Rashs, Pseudomembranou colitis
Term
Mechanism of action of Linezolid?
Definition
Prevents fomation of 70s Initiation Complex
Term
Uses of Linezolid?
Definition
VRE (Vancomycin resistant Enterococcus faecium), VRSA (Voancymycin resistand S. auresus), MSSA/ MRSA, (Methicilli susceptible & resistant S.aureus-nosocomial pnumonia)
Term
What type of effect does Quinupristin/Dalfopristin have?
Definition
BACTERICIDAL, LONG POST-ANTIBIOTIC EFFECT
Term
Uses of Quinupristin/Dalfopristin?
Definition
VRE (Vancomycin resistant Enterococus faecium)
Supporting users have an ad free experience!