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Pharm I - Test # 3 - Serotonin
Fall Semester - 2010 - Pharm Test #3
13
Medical
Graduate
12/14/2010

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Term
Which serotonin agonist is used as an Anxiolytic?
Definition
Buspirone
Term
Which serotonin agonist is used as an appetite suppressant? What is an important note about this med?
Definition
Dexfenfluramine; It is no longer on the market
Term
Which serotonin agonist is used for GI reflux and motility disorders?
Definition
Cisapride
Term
Which serotonin agonist is used for irritable bowel with constipation?
Definition
Tegaserod
Term
Which serotonin agonist group is used for acute migraines and cluster HA? What do these meds end in?
Definition
Triptan Group; end in -triptan
Term
What is serotonin syndrome caused by? Which meds can precipitate Serotonin Syndrome?
Definition
Excess serotonin in the CNS
Meds:
SSRIs
2nd generation anti-depressants
MAOIs
Linezolid
Tramadol
Merperidine
Fentanyl
Ondansetron
Sumatriptan
MDMA
LSD
St. John's Wart
Ginseng
Term
Which 2 serotonin antagonist's meds are used in the treatment of Serotonin Syndrome?
Definition
Cyproheptadine or Chlorpromazine
Term
If a patient present with acute onset of S & S including HTN, Hyperreflexia, tremors, clonus, hyperthermia, hyperactive bowel sounds, diarrhea, mydriasis, agitations, and coma, what condition might you suspect (especially after noting the meds the patient is on)?
Definition
Serotonin Syndrome
Term
Which serotonin antagonist is used in the treatment aimed at altering BT and reducing thromboxane therapy?
Definition
Ritanserin
Term
Which serotonin antagonist is used in the treatment of Nausea and vomiting?
Definition
Ondansetron
Term
What types of tumors can serotonin antagonists help to treat?
Definition
Carcinoid tumors
Term
Which group of serotonin agonists can be used to treat depression?
Definition
SSRIs
Term
What medications can be used to treat migraines?
Definition
Triptans
Ergot Alkaloids
NSAIDs
Beta-Blockers (Propranolol)
CCB (Verapamil)
Antidepressants (Tricyclic and SSRIs)
Anti-seizure Agents (Valproic Acid)
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