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Pharm Giant Condition & When To Use
yeah
120
Pharmacology
Undergraduate 2
10/24/2015

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Cards

Term
Anaphylactic reaction
Definition
Adrenaline
Term
A general aneasthetic with fast induction and recovery
Definition
Nitrous oxide
Term
Day surgery general aneasthetic
Definition
Propofol
Term
A non-depolarising general anaesthetic
Definition
Rocuronium
Term
General anaesthetic that provides the most rapid, reliable onset and only lasts about 5 mins, but not good with digoxin
Definition
Suxamethonium
Term
Local anaesthetic with shorter half life than lignocaine, bot not to be given with antiarrhythmics or drugs that depress cardiac contractility
Definition
Amethocaine
Term
Local anaesthetic with longer half life than lignocaine, but not to be given with antiarrhythmics or drugs that depress cardiac contractility
Definition
Bupivacaine
Term
Reversible local anaesthetic metabolised by the liver
Definition
Lignocaine
Term
Antidote for paracetamol overdose
Definition
Acetylcysteine
Term
Antidote for ingestive toxic substances that are in the GIT. Stops their absorption
Definition
Activated charcoal
Term
Antidote for mild hyperkalaemia or calcium channel blocker poisoning. Not to be used with digoxin
Definition
Calcium gluconate
Term
Treatment for overdose of beta-blockers or calcium channel blockers
Definition
Glucagon
Term
Treatment for opioid overdose
Definition
Naloxone
Term
Most common used beta blocker for angina and hypertension
Definition
Atenolol
Term
Angina in people with cardiac failure
Definition
Glyceryl trinitrate
Term
Drug of choice for arrythmia
Definition
Adeonsine
Term
Arrhythmia, but interacts with warfarin and digoxin. Safe to use with beta blockers and Ca channel blockers
Definition
Amiodarone
Term
Most commonly used as AV block fro atrial fibrillation. Needs to be monitored for hypokalaemia
Definition
Digoxin
Term
Calcium channel blocker used for arrhythmia
Definition
Verapamil
Term
Loop diuretic used for heart failure
Definition
Frusemide
Term
ACE inhibitor used for heart failure and hypertension. Gives a cough
Definition
Perindopril
Term
A K+ sparing diuretic used for heart failure. Acts on the collecting tubule
Definition
Sprionolactone
Term
A statin used for hyperlipidaemia that stops one of the steps in the biosynthesis of cholesterol
Definition
Arvostatin
Term
A calcium channel blocker used for hypertension
Definition
Amlodipine
Term
A thiazide diuretic used for hypertension that works on the ascending limb of the Loop of Henle and the DCT. Electrolyte disturbances if used with loop diuretics
Definition
Hydrochlorothiazide
Term
A sartan and angiotensin II receptor antagonist used for hypertension but can cause hyperkalaemia
Definition
Irbesartan
Term
Used in thromboembolic disease, stops platelets aggregating. Dont use with warfarin, NSAIDs, or probenecid
Definition
Aspirin
Term
A pro-drug used in thromboembolic disease that inhibits the ADP-induced activation of platelets. Can cause bleeding or diarrhoea
Definition
Clopidogrel
Term
Used in thromboembolic disease that predominantly works via antithrombin III accelerating inactivation of clotting factor Xa. Has a more predictable response, longer half-life, and less risk of bleeding
Definition
Enoxaparin (LMWH)
Term
Used in thromboembolic disease and inactivates clotting factors IIa, IXa, Xa, and XIIa. Not absorbed orally
Definition
Heparin
Term
Used in thromboembolic disease and forms a complex with plasminogen leading to the conversion of plasminogen to plasmin
Definition
Streptokinase
Term
Used in thromboembolic disease and inhibits the hepatic production of clotting factors II, VII, IX, and X. Has a therapeutic delay of 2-7 days. Need to monitor
Definition
Warfarin
Term
Used in bone disorders to reduce bone resorption by osteoclasts, hinder recruitment of osteoclasts, and stimulate osteoblasts to produce an inhibitor of osteoclast formation
Definition
Alendronate
Term
The active form of vitamin D
Definition
Calcitriol
Term
A sulphonylurea used in diabetes. Causes insulin to be released. Used when diet, exercise and usually metformin have not worked.
Definition
Gliclazide
Term
The first choice for insulin sensitisers used in diabetes. Also decreases hepatic glucose production
Definition
Metformin
Term
Increases sensitivity to insulin in diabetic patients. Can cause weight gain
Definition
Pioglitazone
Term
Treats hyperthyroidism by interfering with the organification of iodine, but takes 4-6 weeks to be effective. Can interact with warfarin
Definition
Carbimazole
Term
Used to treat hypothyroidism
Definition
Thyroxine
Term
Osmotic laxative that can take 2-3 days to act
Definition
Lactulose
Term
Used for constipation
Definition
Senna
Term
Used to treat diarrhoea. Works on mu-opioid receptors
Definition
Loperamide
Term
A proton-pump inhibitor used to treat GORD/PUD. Generally well tolerated
Definition
Esomeprazole
Term
A competitive H2 receptor antagonist used to treat GORD/PUD. Generally well tolerated
Definition
Ranitidine
Term
Used to treat nausea and vomiting. Crosses the BBB so can block central dopamine receptors - dont give in Parkinson's
Definition
Metclopramide
Term
A 5HT antagonist used to treat nausea and vomiting. Interacts with rifampicin
Definition
Ondansetron
Term
Used to treat obesity by preventing the absorption of about 30% of dietary fat
Definition
Orlistat
Term
Used to treat infections of the CNS caused by pork tapeworms. Need to monitor liver function long term
Definition
Albendazole (a benzimidazole)
Term
A broad-spectrum anti-parasitic drug used to treat roundworm infections. Can also be used to treat scabies. Generally well tolerated
Definition
Ivermectin
Term
Broad-spectrum penicillin
Definition
Amoxycillin
Term
An antibiotic used to treat infections caused by bacteria, including upper respiratory infections, ear infections, skin infections, and urinary tract infections
Definition
Cephalexin
Term
Bacteriostatic broad-spectrum antibiotic that works against both Gram +ve and Gram -ve aerobic and anaerobic microbes. But has caused severe and sometimes fatal blood problems (eg, anemia, low blood platelets, low white blood cell counts)
Definition
Chloramphenicol
Term
A quinolone antibiotic. Can also treat people exposed to anthrax
Definition
Ciprofloxacin
Term
Used to treat many different bacterial infections, such as acne, urinary tract infections, intestinal infections, eye infections, gonorrhea, chlamydia, periodontitis (gum disease), and others
Definition
Doxycycline
Term
A broad spectrum macrolide antibiotic that can be bacteriostatic or bactericidal, depending on conc in blood or tissue
Definition
Erythromycin
Term
An antibacterial drug that has broad Gram -ve spectrum. Can cause nephrotoxicity and ototoxicity. Used to treat severe or serious bacterial infections
Definition
Gentamicin
Term
Used to treat and to prevent tuberculosis (TB)
Definition
Isoniazid
Term
An antibacterial drug active against both Gram +ve and Gram -ve organisms, but only anaerobic ones. Used to treat bacterial infections of the vagina, stomach, skin, joints, and respiratory tract, but will not treat a vaginal yeast infection
Definition
Metronidazole
Term
Effective against Gram +ve bacteria. Used to treat or prevent tuberculosis (TB), as well as reduce certain bacteria in your nose and throat that could cause meningitis or other infections to stop spread to others
Definition
Rifampicin
Term
Used to treat an infection of the intestines caused by Clostridium difficile, which can cause watery or bloody diarrhea. It is also used to treat staph infections that can cause inflammation of the colon and small intestines
Definition
Vancomycin
Term
An antifungal drug often used intravenously for systemic fungal infections
Definition
Amphotericin
Term
Used to treat fungal infections and prevent them in people with weakened immune systems
Definition
Fluconazole
Term
Used to treat or prevent malaria
Definition
Chloroquine
Term
Used to treat uncomplicated malaria (not severe forms), but will not prevent it
Definition
Quinine
Term
Inhibits the replication of herpes simplex viruses 1 & 2, and varicella zoster virus
Definition
Aciclovir
Term
An oral prodrug used in the treatment of influenza A and B and in the prophylaxis of influenza
Definition
Oseltamivir
Term
A nucleoside reverse transcriptase inhibitor used in the treatment of HIV infection
Definition
Zidovudine
Term
Used to treat oestrogen-dependent breast cancer
Definition
Anaztrozole
Term
Used to treat several forms of cancer. Has both cytotoxic and immunosuppressive actions
Definition
Cyclophosphamide
Term
Used to treat cancer of the colon, rectum, breast, stomach, or pancreas
Definition
Fluorouracil
Term
Used to treat certain types of cancer of the breast, skin, head and neck, or lung. It is also used to treat severe psoriasis and rheumatoid arthritis.
Definition
Methotrexate
Term
A SERM used to treat breast cancer
Definition
Tamoxifen
Term
Used to treat certain types of breast cancer or stomach cancer
Definition
Trastuzumab
Term
Used to prevent organ rejection after a kidney, heart, or liver transplant. It is also used to treat severe psoriasis or severe rheumatoid arthritis.
Definition
Cyclosporine
Term
An immunomodulator used in hairy cell leukemia, malignant melanoma, AIDS-related Kaposi's sarcoma, follicular non-Hodgkin's lymphoma
Definition
Interferon Alfa
Term
A glucocorticoid used to treat inflammation, eg skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders
Definition
Prednisolone
Term
Lowers the immune system. Given in a combination treatment with cyclosporine and a steroid medicine to prevent the body from rejecting a transplanted organ
Definition
Sirolimus
Term
DMARS used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, Crohn's disease, and ankylosing spondylitis. NO drug interactions
Definition
Infliximab
Term
Affects a substance in the body that causes inflammation, tissue damage, and diarrhea. Used for ulcerative colitis and rheumatoid arthritis when other meds have not worked
Definition
Sulfasalazine
Term
Used in patients with multiple recurrent gout attacks and kidney disease caused by uric acid or urate deposition
Definition
Allopurinol
Term
Used to treat or prevent attacks of gout
Definition
Colchicine
Term
An NSAID that inhibits COX thereby inhibiting prostaglandin synthesis - COX-1 and COX-2
Definition
Ibuprofen
Term
More selective for COX-2 so has analgesic and anti-inflammatory properties with less adverse effects on the gastrointestinal tract than other NSAIDs
Definition
Meloxicam
Term
A LABA
Definition
Eformoterol
Term
Used to treat more severe forms of asthma
Definition
Fluticasone
Term
A SABA
Definition
Salbutamol
Term
Used as first-line ovulation induction in women with anovoluntary infertility or PCOS
Definition
Clomiphene
Term
Contracts the uterine muscle and increases milk release during lactation
Definition
Oxytocin
Term
Prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body. DHT is involved in the development of benign prostatic hyperplasia (BPH)
Definition
Finasteride
Term
What viagra is
Definition
Sildenafil
Term
An alpha-blocker that relaxes the muscles in the prostate and bladder neck, making it easier to urinate. Can improve urination in men with benign prostatic hyperplasia (enlarged prostate)
Definition
Tamsulosin
Term
An antipsychotic that has lower potency at D2 receptors than another one but has more anticholinergic side effects. Is a phenothiazine
Definition
Chlorpromazine
Term
A buteophenone antipsychotic that has ewer anticholinergic effects than another and doesnt cause sedation, but more extrapyramidal effects
Definition
Haloperidol
Term
Used to treat anxiety disorders. A benzodiazepine
Definition
Diazepam
Term
Treats insomnia, but can cause unexpected sleep related behaviours, which are made worse by drinking alcohol
Definition
Zolpidem
Term
A tricyclic antidepressant (TCA) whose withdrawals can have anticholinergic effects
Definition
Amitriptyline
Term
The most commonly used treatment for depression
Definition
Fluoxetine (an SSRI)
Term
Used to treat the manic episodes of manic depression
Definition
Lithium
Term
A non-selective irreversible MAO inhibitor used to treat depression and bipolar. Can cause weight gain. Usually given after other anti-depressants have been tried without successful treatment of symptoms
Definition
Phenelzine
Term
Used to treat opioid dependence
Definition
Methadone
Term
First line treatment for partial seizures and generalised tonic-clonic
Definition
Carbamazepine
Term
First line treatment for generalised tonic-clonic and absence/petit-mal seizures, second line treatment for partial seizures
Definition
Valproate
Term
First line treatment for absence/petit-mal seizures
Definition
Ethosuxemide
Term
Second line treatment for all seizure types (Na and Ca channel blocker)
Definition
Lamotrigine
Term
Second line treatment for partial seizures and generalised tonic-clonic seizures (Na channel blocker)
Definition
Phenytoin
Term
Second line treatment for partial seizures (HVA seizures)
Definition
Gabapentin
Term
Second line treatment for partial seizures and generalised tonic-clonic seizures (Na channel blocker)
Definition
Topiramate
Term
Second line treatment for partial seizures (GABA agonist)
Definition
Tiagabine
Term
Used to treat Parkinson's Disease
Definition
Benztropine
Term
Used to treat Parkinson's Disease and is a dopamine agonist that does not require enzymatic conversion to active metabolite
Definition
Bromocriptine
Term
Used to treat Parkinson's Disease. A metabolic precursor of dopamine
Definition
Levodopa
Term
Used in Parkinson's Disease. Is an irreversible inhibitor of MAO-B
Definition
Selegiline
Term
Used in Parkinson's to help treat some of the muscarinic side effects
Definition
Benzotropine
Term
Used in Parkinson's Disease to prevent L-dopa being metabolised in the periphery
Definition
Carbidopa
Term
Used in Parkinson's Disease to prevent L-dopa being metabolised in the periphery
Definition
Benserazide
Term
Used in Parkinson's Disease to prevent COMT metabolism competing with l-dopa for transport across BB
Definition
Tolcapone
Term
Used in Parkinson's Disease to prevent COMT metabolism competing with l-dopa for transport across BB
Definition
Entacapone
Term
DA agonist used in Huntington's Disease
Definition
Chlorpromazine
Term
GABA agonist used to treat Huntington's Disease
Definition
Baclofen
Term
Used to treat Huntington's Disease as it depletes DA in the brain
Definition
Tetrabenazine
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