Term
|
Definition
| 50%, Carbonic Anhydrase Inhibitor, inhibits NaHCO3 reabsorption |
|
|
Term
|
Definition
| Proximal convoluted Tubule |
|
|
Term
| Azetazolamide- Adverse effects |
|
Definition
|
|
Term
|
Definition
35%, Blocks Na+/K+/2Cl- cotransporter
Strongest
Useful in edema, heart failure, renal failure, acute hypercalcemia |
|
|
Term
|
Definition
| Loop of Henle, thick ascending limb |
|
|
Term
| Furosemide-Adverse effects |
|
Definition
Loss of magnesium and calcium
Hypovolemia (dehydration), hypokalemia
Hearing loss, especially with aminoglycoside antibiotics
Hyperglycemia, hyperuricemia |
|
|
Term
| Hydrochlorothiazide- mechanism |
|
Definition
10%, Blocks Na+/Cl- cotransporter by binding to it,
Moderate
Hypercalciurea, osteoporosis, diabetes insipidus |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Hyperglycemia, hypokalemia, hyperuricemia |
|
|
Term
|
Definition
Aldosterone receptor antagonist, binds but doesn't produce effect
K+ sparing
Compensatory salt retaining
Good hyperaldosteronism |
|
|
Term
|
Definition
| Cortical collecting duct, aldosterone receptor |
|
|
Term
|
Definition
Transient natriuresis
Hyperkalemia
Gynecomastia, menstrual abnormalities |
|
|
Term
| Amiloride/Triamterene-mechanism |
|
Definition
Blocks epithelial Na+ channels,
K+ sparing
Weak |
|
|
Term
| Amiloride/Triamterene-site |
|
Definition
| Cortical collecting duct, ENaC |
|
|
Term
| Amiloride/Triamterene-adverse |
|
Definition
|
|
Term
|
Definition
Osmotic diuretics, increases Osmolality of plasma and draws from interstitial fluid, filtered into glomerulus not reabsorbed in tubule, not metabolized by body
Acute glaucoma, acute renal failure, cerebral edema |
|
|
Term
|
Definition
|
|
Term
|
Definition
Increase ECF volume can lead to pulmonary congestion, heart failure
Retards water reabsorption in proximal tubule |
|
|
