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Pharm Exam 3
pharm 3
72
Pharmacology
Graduate
11/19/2015

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Cards

Term
Buprenorphine
Definition
opioid partial agonist
Term
Nalbuphine
Definition
opioid agonist-antagonist
Term
Levomethadyl
Definition
opioid
Term
Levorphanol
Definition
opioid
Term
Butorphanol
Definition
opiod agonist-antagonist - no resp depression
Term
Pentazocine (Talwin)
Definition
opioid agonist-antagonist
Term
Dezocine (Dalgan)
Definition
opioid agonist-antagonist
Term
Tapentadol
Definition
opioid
Term
Nalmefene (Revex)
Definition
opioid antagonist
Term
Naltrexone
Definition
opioid antagonist - pt must be opioid free
Term
Baclofen
Definition
GABA activator anti spasmic
Term
Pentoxifylline
Definition
-increases blood flow/oxygenation
-opioid adjunct
Term
What 4 drugs increase pain?
Definition
Haloperidol
Chlorpromazine
Pimozide
Promethazine
Term
Causes Reyes Syndrome
Definition
Aspirin
Term
NSAIDs plus what else, increase bleeding risk?
Definition
SSRI's
Term
Refecoxib
Definition
Cox2 selective. pulled for MI incidences after 18 months
Term
Quinidine, Chlorpheniramine, Fluoxetine, and Paroxitene all inhibit 2D6, affecting what drugs?
Definition
Codeine and Tramadol
Term
Epinephrine causes vasoconstriction interactions with what antidepressant?
Definition
TCA's
Term
What 4 types of drugs don't mix well with epinephrine/vasoconstrictors?
Definition
Adrenergic blocking agents
SSRIs
Digitalis Glycosides
COMT inhibitors
Term
What is the best local for children?
Definition
2% lido with epi
Term
How does Oraverse work?
Definition
non selective alpha blocker. not used for OD or hypertensive crisis
Term
Methotrexate
Definition
DMARD for RA...elevates Adenosine....used at high doses for cancer
Term
Hydroxychloroquine
Definition
DMARD for RA....micosal pigmentation
Term
Sulfasalazine
Definition
DMARD for RA
Term
Leflunomide (Arava)
Definition
New, traditional DMARD
Term
Azathioprine
Definition
DMARD for RA...decreased purine synth
Term
Cyclosporine A
Definition
DMARD for RA.....gingival hyperplasia
Term
Gold
Definition
DMARD for RA...stomatitis (swelling of mouth) and taste change
Term
Cyclophosphamide
Definition
DMARD for SEVERE RA
Term
Infliximab, Golimumab
Definition
TNF-a antagonists for RA....depress immune system
Term
Tofacitinib
Definition
for RA......inhibits Janus Kinase
Term
Colchicine
Definition
treat and prevent gout
Term
Allopurinol
Definition
xanthine oxidase inhibitor for Gout
Term
Febuxostat
Definition
xanthine oxidase inhibitor for Gout
Term
Probenecid
Definition
Gout. inhibits reabsorption or Uric acid
Term
Sulfonylurea
Definition
Type 2 diabetes
blocks K channels
Term
Acetohexamide, chorpropamide, tolazamide, tolbutamide,
Definition
first gen sulfonylureas
Term
Glimepride, Glipizide, Glyburide
Definition
second gen sulfonylureas
Term
sulfonylureas dont mix well with what drugs?
Definition
NSAID's
natifungals
Term
Repagliuide
Definition
K channel blocker for diabetes
for patients allergic to sulfonylureas
Term
Metformin
Definition
-diabetes
-improves tissue uptake of glucose
-NOT an insulin releaser
Term
Pioglitazone, Rosiglitazone
Definition
Diabetes
increase insulin sensitivity of tissues

HEART FAILURE AND MI AND BLADDER CANCER
Term
Acarabose and Miglitol
Definition
alpha glucosidase inhibitors for diabetes
Term
What is cretinism?
Definition
HYPOthyroidism in kids...retarded and facial abnormalities
Term
Levothyroxine
Definition
treats HYPOthyroid
Term
Liothyronine
Definition
treats HYPOthyroid
Term
Liotrix
Definition
treats HYPOthyroid
Term
Methimazole
Definition
treats HYPERthyroid....thyroglobulin and Iodine step
Term
Carbimazole
Definition
treats HYPERthyroid....thyroglobulin and Iodine step
Term
Propylthiouracil (PTU)
Definition
treats HYPERthyroid....thyroglobulin and Iodine step
Term
Lugols
Definition
treats HYPERthyroid...prevent T3 and T4 from entering blood
Term
Radioactive Ioidide
Definition
treats HYPERthyroid
Term
Alendronate (Fosamax)
Definition
bisphosphonate for osteoporosis
Term
Zometa
Definition
cancer therapy for osteoporosis IV only
Term
What drug class causes ONJ
Definition
Bisphosphonates
Term
DES
Definition
morning after pill
Term
Beclamethasone
Definition
inhaled steroid for asthma
Term
Flunisolide
Definition
inhaled steroid for asthma
Term
Fluticasone
Definition
inhaled steroid for asthma
Term
Triamcinolone
Definition
inhaled steroid for asthma
Term
AEs of inhaled steroids?
Definition
candidal infections
dry/hoarse mouth
NO Hypo-pit-adrenal axis suppression
Term
AEs of systemic steroids?
Definition
suppression of Hyp-pit-adrenal axis
Term
Prednisolone
Definition
oral systemic glucocorticoid for asthma
Term
Cromolyn Sodium, Nedocromil
Definition
-non steroidal prophylactic drugs for asthma.
-used before exercise
Term
Zileuton (Zyflo)
Definition
5-Lipoxygenase Inhibitor for Asthma
-interacts with warfarin
Term
Zafirlukast
Definition
Leukotriene receptor antagost for asthma
-interacts with warfarin
Term
Isoproterenol
Definition
B1 and B2 agonist for asthma. produces heart issues
Term
Metaproterenol (Alupent)
Definition
Beta 2 selective agonist for asthma med
Term
Albuterol (Proventil)
Definition
Beta 2 selective agonist for asthma
Term
Salmeterol
Definition
Longest acting beta 2 selective agonist for asthma
Term
Theophylline (theodur)
Definition
-Blocks phosphodiesterase 3 and 4
-for asthma
-stimulates catecholamines
-Erythro and cipro inc levels
-PHenobarbital dec levels
Term
Ipatropium (Atrovent)
Definition
-Antimuscarinic for asthma
-bad taste and xerostomia
-slower than B2 agonists
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