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Pharm Exam #2 (Part 1)
contraception flashcards
14
Pharmacology
Undergraduate 2
10/20/2010

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Cards

Term
contraception MOA
Definition
prevent sperm from entering the vagina/cervix
immobilization or inactivation of sperm
fertility awareness
prevention of ovulation/implantation
sterilization
Term
estrogen contraceptive effects
Definition
inhibition of ovulation (effect on the hypothalamus)
inhibit implantation (alter uterine secretions)
accelerate ovum transport
luteolysis (degeneration of corpus luteum)
Term
progestin contraceptive effects
Definition
increase cervical mucus vicosity capacitation inhibited
slow ovum transport
inhibit implantation
inhibit ovulation
Term
COC one year effectiveness
Definition
perfect use (0.0%), typical use (3%)
Term
estrogen excess effects
Definition
nausea
breast tenderness
headaches
weight gain
irritability
Term
estrogen deficiencies
Definition
amenorrhea
depression
hot flashes
irritability
decreased libido
atrophic vaginitis
Term
progestin excess effects
Definition
noncyclic weight gain
tiredness
acne
oily skin
nausea/vomiting
edema
breast tenderness
Term
progestin deficiency effects
Definition
late BTB days 8-21
heavy menstrual flow
delayed withdrawal bleeding
weight loss
Term
contraceptive benefits
Definition
highly effective
effective immediately if started by day 7 of menstrual cycle
do not interfere with intercourse
few side effects
convenient and easy to use
Term
noncontraceptive benefits
Definition
protect against ovarian and endometrial cancer
decreased benign breast disease
decreased rate of ectopic pregnancy
PMS reduction/cramping
acne
Term
absolute contraindications for oral contraceptives
Definition
present/past thrombophlebitis, thromboembolic diorders, cerebral vascular disease, coronary occlusion
markedly impaired liver function
known or suspected breast cancer
undiagnosed vaginal bleeding
known or suspected pregnancy
Term
cautions for oral contraceptives
Definition
migraine headache (old studies indicate more strokes)
hypertension (OK if less than 35 and otherwise healthy)
diabetes
elective surgery (dc 4 weeks before elective surgery to decrease thrombosis)
gallbladder disease
greater than 35 y.o. and heavy smoker (more than 15 per day)
greater than 40 y.o. and additional cardiovascular risk factors
Term
patient education
Definition
when to start: 1st tablet on the 1st day of menses or 1st tablet on the first Sunday after beginning menstruation and use alternate form of contraception for the 1st seven days of COC use
Term
patient education (cont.)
Definition
not a barrier to STDs
take at exact time each day
expect menses during the 7 inactive pill days
28 vs. 21 day packs
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