Term
What is the main clinical use of stimulants (amohetamines)? |
|
Definition
|
|
Term
What Sx of ADHD do stimulants treat? |
|
Definition
core Sx: impulsivity, inattention, & motor restlessness |
|
|
Term
|
Definition
6+ Sx (from A or B) present for 6+ months to a point that is disruptive & inappropriate for developmental level
A) List of inattention Sx B) List of Hyperactive/inpulsive Sx |
|
|
Term
How effective are stimulants are Tx of ADHD? |
|
Definition
so much so that combined CBT is not needed |
|
|
Term
What are the 5 amphetamines? |
|
Definition
1) Amphetamine 2) DA 3) Methamphetamine 4) Methylphenidate 5) Dextroamphetamine |
|
|
Term
|
Definition
release monoamines thru non-exocytotic mechanism |
|
|
Term
What form of stimulants have been developed for stable effect throughout the day? |
|
Definition
|
|
Term
|
Definition
1) ADHD 2) excessive daytime sleepiness (narcolepsy, sleep apnea, etc) 3) appetite suppressants (historically) |
|
|
Term
|
Definition
headaches that are: 1) unilateral 2) pulsatile/throbbing 3) associated with N/V 4) sufficient intensity to interrupt daily activities 5) last 4-72 hrs if untreated |
|
|
Term
Who is affected by migranes? |
|
Definition
|
|
Term
What tends to be the triggers for mirgranes? |
|
Definition
|
|
Term
|
Definition
|
|
Term
Tx
migranes (not severe, no vomiting) |
|
Definition
|
|
Term
|
Definition
1) Triptans 2) Dihydroergotamine |
|
|
Term
|
Definition
5-HT1B/1D receptor agonists => inhibition of neurotransmitter release |
|
|
Term
When in combination with what do triptans seen to be most effective in treating migranes? |
|
Definition
NSAIDs (may be given in combination with antiemetics as well) |
|
|
Term
|
Definition
|
|
Term
When in the migrane course should triptans be administered? |
|
Definition
as early as possible (early intervention is important) |
|
|
Term
Why shouldn't triptans be given as monotherapy? |
|
Definition
Alone, not much better than NSAIDs & have a high cost |
|
|
Term
|
Definition
1) sumatriptan 2) fovatriptan |
|
|
Term
|
Definition
1) β blockers (propanolol, timolol, metoprolol) 2) AED (valproate, topiramate) 3) TCAs 4) Behavioral therapies |
|
|
Term
|
Definition
|
|