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Pharm Exam #2 - Antipsychotics
Typical and Atypical Antipsychotics
11
Pharmacology
Graduate
11/01/2010

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Cards

Term
Haloperidol
Definition
TYPICAL ANTIPSYCHOTIC
high potency
high extrapyramidal symptoms
low neurological side effects

SE: (early onset reversible) acute dystonia, parkinsonims, akathisia, (late onset sometimes reversible) tardive dyskinesia
Term
Fluphenazine
Definition
TYPICAL ANTIPSYCHOTIC
high potency
high extrapyramidal symptoms
low neurological side effects

SE: (early onset reversible) acute dystonia, parkinsonims, akathisia, (late onset sometimes reversible) tardive dyskinesia
Term
Perphenazine
Definition
TYPICAL ANTIPSYCHOTIC
medium potency
medium extrapyramidal symptoms
medium nonspecific side effects

SE: (early onset reversible) acute dystonia, parkinsonims, akathisia, (late onset sometimes reversible) tardive dyskinesia
Term
Chlorpromazine
Definition
TYPICAL ANTIPSYCHOTIC
low potency
low extrapyramidal symptoms
high non-neurological side effects

SE: (early onset reversible) acute dystonia, parkinsonims, akathisia, (late onset sometimes reversible) tardive dyskinesia
Term
Thioridizine
Definition
TYPICAL ANTIPSYCHOTIC
low potency
low extrapyramidal symptoms
high non-neurological side effects

SE: (early onset reversible) acute dystonia, parkinsonims, akathisia, (late onset sometimes reversible) tardive dyskinesia
Term
Clozapine
Definition
ATYPICAL ANTIPSYCHOTIC
can be effective in patients who are resistant to other antipsychotics, reserved for treatment resistant patient bc of life threatening SE of agranulocytosis
also known to increase salivation and cause seizures

SE: sedtaion, weight gain, some EPS
Term
Risperidone
Definition
ATYPICAL ANTIPSYCHOTIC
can cause EPS at higher doses
weight gain, increased prolactin, sedation
Term
Olanzapine
Definition
ATYPICAL ANTIPSYCHOTIC
SE: sedation, weight gain, some EPS
Term
Quetiapine(Seroquel)
Definition
ATYPICAL ANTIPSYCHOTIC
SE: weight gain, sedation
Term
Ziprasidone
Definition
ATYPICAL ANTIPSYCHOTIC
can cause cardiac arrhythmia and has risk of death (rare SE due to prolongation of QT interval by inhibiting a K+ current)
mostly problem at higher doses and in older, more frail patients

SE: possible weight gain, EPS, sedation
Term
Aripiprazole (Abilify)
Definition
ATYPICAL ANTIPSYCHOTIC

SE: possible weight gain, EPS, sedation
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