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pKa = pH - log (A-)/(HA)
Or: B/HB+ |
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VD=Amount in Body/Plasma [Conc] |
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Loading Dose = VD* CpE
CpE = Effective Plasma [Conc] |
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Maintenance Dose = VD (CpE - CpM)
Volume of Dist * (Effective [Plasma] - Min [Plasma]) |
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Cpss = Infusion Rate (mg/hr) / Clearence of Total Body (mg/hr) |
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Clr = [conc] Urine/Plasma * Collection volume/time |
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First-order rate constant |
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Liver Extaction Ratio = (Ca - Cv)/Ca
Conc that enters - conc that leaves liver over conc that enters |
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Bioavailability = AUCoral / AUCiv
Area Under Curve |
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