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Pharm Block 13 Review
KYCOM Cumelative
74
Pharmacology
Graduate
02/27/2014

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Cards

Term
name 2 ACEI
Definition
catopril
lsinopril
Term
use of ACEI 3
Definition
HTN
CHF
in diabetic renal benifit
Term
SE of ACEI 2
Definition
cough
angioedema: rapid sewlling of face after 1st dose
Term
contraindications of ACEI 1
Definition
pregnancy
Term
4 BB and their MOA
Definition
propranolol - no selective
desmolol, atenolol, metoprolol - B1 selective
Term
which BB are prefered in cardiac conditions
Definition
B1 selective
Term
contraindications to BB 3
Definition
asthma
diabetes
peripherial vascular disease: vasospastic angina
Term
SE BB 4
Definition
slows heart down
decreased CO
fatigue
never abruptly DC
Term
Use BB 4
Definition
HTN
CHF
anti-arrhythmic SVT class 2
angina
Term
use esmolol, why
Definition
BB only used in arrhythmia
short t1/2 10 min
Term
name one ARB and it MOA
Definition
losartin
block ANG II receptor, benifits similar to ACEI
Term
use of ARB 3
Definition
HTN
CHF
renal benifit in diabetes
Term
SE of ARB
Definition
no cough
Term
contraindications of ARB 2
Definition
pregnancy
hyperkalemia
Term
1 vasodilator
Definition
hydralazine
Term
MOA hydralazine
Definition
vasodilates using NO with specificity for arterioles
Term
MOA nitrates
Definition
work through NO with sepcificity to VEINS
Term
use hydralazine 2
Definition
HTN
CHF - back up if unable to use ACEI/ARB
Term
SE hydralazine
Definition
drug most likley to cause drug induced lupus in slow acetylators
Term
central A2 agonist 1
Definition
methyldopa
Term
MOA methyldopa
Definition
main effect inside CNS
stimulates A2 inhibitory recetors decreasing sympathetic output
Term
SE methyldopa 2
Definition
fatigue
hemolytic anemia
Term
use methyldopa
Definition
HTN, esp in pregnancy
Term
MOA carvedilol
Definition
A and B blocker
Term
use carvedilol 2
Definition
HTN
CHF
Term
MOA slidenafil
Definition
block PDE5 increasing cGMP and NO which causes vasodilation
Term
use slidenafil 2
Definition
pulmonary HTN
erectile dysfunction
Term
contraindications slidenafil
Definition
never use with nitrates, both work in same pathway too much dilation occurs
Term
3 CCB
Definition
verapamil
diltaziam
amidopine
Term
MOA verapamil
Definition
cardiodepressant
blocks L type Ca channels on heart
Term
MOA ditilaziam
Definition
cardiodepressant
blocks L type Ca channels on heart mostly
Term
MOA amlodipine
Definition
vasodilates, drops BP
blocks L type Ca channels on vessels
Term
use of verapamil 3
Definition
HTN
angina
arrhythmia SVT class 4
Term
SE cerapamil
Definition
constipation
Term
use ditilaziam 3
Definition
HTN
angina
arrhythmia SVT class 4
Term
use of amlodipine 3
Definition
HTN
angina
Term
SE amlodipine 2
Definition
reflex tachycardia
gingival hyperplasia
Term
MOA digoxin
Definition
positive inotrope
inhibits Na/K ATPase on cardiac myosites
when Na goes up Ca does too and gets stored in sarcoplasmic reticulum so not it releases more causing positive inotropic effect
Term
use digoxin
Definition
arrhythmia SVT
Term
SE digoxin 2
Definition
low theraputic index
arrhythmia
blurry yellow vision
Term
contraindications of digoxin
Definition
hypokalemia can enhance digoxin toxicity
digoxin and K bind same site on Na/K ATPase
Term
4 drugs used for ventricular tachycardia
Definition
procanamide
lodicaine
sotalol
amiodarone
Term
4 types of drugs used for SVT
Definition
CCB
BB
adenosine
digoxin
Term
2 drugs used to ventricular tachycardia and SVT
Definition
satolol
amiodarone
Term
2 drug only used for SVT
Definition
adenosine
Term
Procanamide: type, MOA, use
Definition
1A
block Na and K
ventricular arrhythmia
Term
lidocainel type, moa, use
Definition
1B
BB
ventricular arrhythmia
Term
satolol: type, MOA, use
Definition
3
block K and BB
any arrhythmia
Term
amioderone: type, MOA, use
Definition
3
block Na, K, Ca, BB
any arrhythmia
Term
SE procanamide 2
Definition
lupus in slow acetylators
torsades
Term
SE of sotalol
Definition
torsades
Term
SE amiodarone4
Definition
torsades - low risk
liver damage
pulmonary fibrosis
thyroid problems - due to iodine
Term
MOA adenosine
Definition
stimulate adenosine receptors (Gi coupled so still inhibitory(
short half life 8s
Term
2 Na channel blocker anti convulsants
Definition
phenytoin
carbamazepine
Term
MOA lamotrigine
Definition
Na channel blocker
glutamate inhibitor
Term
MOA ethosuxamide
Definition
block T type Ca channels
Term
MOA lerazepam
Definition
status epilepticus
Term
SE phenytoin 4
Definition
teratogenic
gingival hyperplasia
p450 inducer
zero order kinetucs
Term
SE carvamazepine 2
Definition
teratogenic
p450 inducer
Term
SE valproic acid 3
Definition
liver problems
hyperammonemia
teratogenic
Term
use ethosuxamide
Definition
absence seizure
Term
use lorazepam
Definition
status epilepticus
Term
use lamotrigine
Definition
most seizures
Term
SE lamotrigine
Definition
DC if any sign of rash could be SJS
Term
3 opioids
Definition
morphine
meperidine
buprenorphine
Term
MOA morphine
Definition
mu agonist
Term
MOA merperidine
Definition
mu agonist
Term
MOA burenophine
Definition
Mu partial agonist
Term
signs of morphine OD 4
Definition
meiosis
depressed respiratory - fatal
decreased GI/GU
gall bladder spasms
Term
SE meperidine 2
Definition
decreased respiration
serotonin syndrome
Term
SE buprenorphine
Definition
when you put it with a full Mu agonist it causes withdrawl
Term
MOA naloxone
Definition
mu antagonist
IV antidote to quickly reverse opioid action
Term
MOS sumatriptan
Definition
5HT1D agonist
vasoconstriction
Term
use sumatriptan
Definition
acute migraine
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