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Pharm Chpt 43
Respiratory system
35
Pharmacology
Undergraduate 1
03/26/2013

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Term
Oxygen is necessary for energy for ____ metabolism?
Definition
cellular
Term
When ____ supply is inadequate, cell function is impaired?
Definition
O2
Term
When O2 is absent, cells ____?
Definition
die
Term
Permanent brain damage occurs within 4-6 minutes of ____?
Definition
anoxia
Term
I addition to providing oxygen to all body cells, the respiratory system also removes ____ ____ , a major waste product of cell metabolism?
Definition
carbon dioxide
Term
Excessive accumulation of CO2 amages or kills body cells and reduces respiratory ____,causing cellular death?
Definition
acidosis
Term
The efficiency of the respiratory system depends on the quality and quantity of air inhaled, the patency of air passages, the ability of the lungs to expand and contract, and the ability of O2 and CO2 to cross the ____-_____ membrane?
Definition
alveloar-capillary
Term
What are the four parts of repirations?
Definition
Ventilation
Perfusion
Diffusion
Breathing regulation
Term
What is the definiton of Respiration?
Definition
Process of gas exchange between lung and blood.
O2 is obtained, CO2 is eliminated.
Term
Ventilation
Definition
The movement of air between the atmosphere and the alveoli of the lungs.
Term
Perfusion
Definition
Blood flow through the lungs
(tissue & alveoli)
Term
Diffusion
Definition
The process by which O2 and CO2 are transferred between alveoli & blood, and between blood and body cells.
Term
Carbon dioxide
Definition
Combines with hemoglobin in the cells for return to the lungs and elimination from the body.
Term
Musculoskeletal system
Definition
Participates in chest expansion & contraction.
Term
Pulmonary circulation system transports ___ & ___?
Definition
O2 & CO2
Term
O2 attaches to hemoglobin at ____ level, transports to cells?
Definition
capillary
Term
CO2 attached to hemoglobin in cells for return to the ___, for eliminatin from body?
Definition
lungs
Term
Pulmonary arteries transport deoxygenated blood ____ to lungs
Definition
away
Term
Pulmonary veins return oxgenated blood ____ the heart?
Definition
to
Term
The nervous system regulates the rate & depth of respiration by the respiratory center.
Name the three areas?
Definition
Medula oblongata
Pneumotaxic center in the pons
Apneutic center in the reticular formation.
Term
The nervous system regulates the rate & depth of respiration by the respiratory center.
The respiratory center is stimulated by ____ CO2 levels?
Definition
increased
Term
You are caring for a pt. w/ COPD. You review lab results you find his CO2 levels is abnormally high. An elevated CO2 level in this pt. may lead to which condition?
Definition
decreased need for supplemental O2

When the center is stimulated, the rate & depth of breathing are increased. an excessive CO2 is exhaled. A lesser stimulus to the respiatory center is decreased oxygen in arterial blood.
Term
Which of the following does the nervous system stimulate the cough reflex to do?
Definition
protect the lungs from harmful particles
Term
The diaphragm and external muscles produce which phase of respiration?
Definition
inspiration
Term
The abdominal and internal intercostal muscles are the muscles of which phase of respiration?
Definition
expiration
Term
Overall, normal respiration requires atmospheric air containing at least what percentage of oxygen?
Definition
21%
Term
Respiratory medications.
More effective in relieving symptoms than in curing underlying disorders.
Definition
brochodilation
anti-inflammatory agents
antihistamines
nasal decongestats
antitussive
cold remedies
Term
The respiratory system is subject to many disorders that interfere with respiration and other lung functions.
Name the five disorders?
Definition
Resiratory tract infections
Allergic disorders
Inflammatory disorders
Conditions that obstruct airflow
Lung injuries
Term
Name the respiratory disorder that obstruct airflow?
Definition
excessive respiratry secretions
COPD
asthma
Term
Name the respiratory disorder that are lung injuries?
Definition
asthma
pulmonary edema
ARDS=acute respiratory distress syndrome.
Term
Normal repiration requires what four things?
Definition
Atmospheric air at least 21%.
Adequate ventiltion.
Adequate diffusion of O2 & CO2.
Adequate perfusion & sufficient hemoglobin.
Term
Adequate ___ requires patent airways, expansion, contraction of chest & lungs, maintenance of a normal range of intrapulmonic & intrapleural pressure.
Definition
ventilation of 40-50%
Normal breathing 16-20 times/per min.
500 mL air insired & expired breath(total volume)
Term
What is the normal breathing rate per minute?
Definition
16-20 times
Term
How many mL's of inspired & expired breath (title breaths) are needed and how many times do they occur to ventilate more alveoli?
Definition
15
6-10 times
Term
Respiratory muscles and nervous system
Definition
Breathing regulation
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