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Pharm-assessment 4
Autacoids
17
Pharmacology
Graduate
08/20/2010

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Cards

Term
PGE1-Alprostadil
(Cardio)
Definition
lower BP, dilate coronary vessels
also suppresses arrhythmias
tx congenital heart defect (infant ductus arteriosis)
Term
PGE1-Alprostadil
(Urology)
Definition
tx erectile dysfunction
Term
PGE1-Misoprostol
Definition
decrease acid and pepsin secretions
increase peristalsis
tx gastric ulcers
Term
PGE1-Rioprostil
Definition
decrease acid and pepsin secretions
increase peristalsis
tx gastric ulcers
Term
PGE1-Gemeprost
Definition
relaxes uterus, contracts uterus in pregnant women
used to dilate cervix for uterine exam
Term
PGE2-Dinoprostone (Cervidil)
Definition
relaxes uterus, contracts uterus in pregnant women
used to dilate cervix for uterine exam, induce abortion, decrease postpartum hemorrhage
can cross BBB to cause hyperthermia
Term
PGI2-Epoprostenol (Flolan)
(Cardio)
Definition
decrease BP, dilate coronary vessels
very unstable
tx congenital heart defects, pulmonary HTN
Term
PGI2-Trepostinil
Definition
decrease BP, dilate coronary vessels
very unstable
tx congenital heart defects
Term
PGI2-Beraprost
Definition
decrease BP, dilate coronary vessels
very unstable
tx congenital heart defects, pulmonary HT
Term
PGI2-Carbacyclin
Definition
decrease acid and pepsin secretion, increase peristalsis
decreases platelet aggregation
tx gastric ulcers, used as anticoagulant
Term
PGI2-Iloprost
Definition
decrease acid and pepsin secretion, increase peristalsis
decreases platelet aggregation
tx gastric ulcers, used as anticoagulant, pulmonary HTN
Term
PGF2aplha-Dinoprost
Definition
contracts pregnant and non-pregnant uterus
induce labor and abortion
Term
PGF2alpha-Carbaprost
Definition
contracts pregnant and non-pregnant uterus
induce labor and abortio
Term
PGF2alpha-Latanoprost (Xalatan)
Definition
tx for glaucoma
increases outflow of aqueous humor via uvulosclera output
side efx: permanent change of eye color to brown
Term
Xalacom
Definition
combination of Latanprost (Xalatan) and Timolol to treat glaucoma
Term
Niacin (Vitamin B3)
Definition
tx atherosclerosis by increasing HDL levels
side efx: skin flushing due to increase in PGD2
Term
Cordaptive
Definition
combination of Niacin and Laropiprant
tx atherosclerosis without skin flushing
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