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Glucocorticoid, used to initiate therapy |
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Decreases Tcell activation |
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inhibits IL1 and TNF-α release |
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BRM, TNF-α Receptor-like protein |
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BRM, Chimeric (mouse), antibody to TNF-α |
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BRM, Fully-human antibody to TNF-α |
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BRM, IL1 Receptor antagonist |
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BRM, Reduces Tcell activation/Incrases Tcell apoptosis |
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BRM, IL6 receptor antagonist |
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BRM, anti-CD20, reduces Bcells |
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Gout, prevents tubulin polymerization --> reduces pain and inflammation fast |
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Gout, uricosuric agent, organic acid competes with urate for reabsorption Sfx: GI irritation, low urate can induce acute gout, reduced secretion of penicillin |
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Gout, Xanthine oxidase competitive inhibitor (alloxanthine non-competitive inhibitor) Sfx: acute attacks of gout possible initially, urate mobilized from tissues |
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