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Pharm - antilipid - test 2
a
50
Pharmacology
Undergraduate 2
10/12/2011

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Term
200
Definition
desired cholestrol level is less than ______
Term
150
Definition
desired triglyceride level is less than ______
Term
59
Definition
desired level of HDL is greater than ____
Term
100
Definition
desired level of LDL is less than ______
Term
lifestyle change
Definition
1st treatment for hyperlipidemia
Term
4 months
Definition
when treating hyperlipidemia, labs must be monitored every ________
Term
statins
Definition
HMG-CoA Reductase Inhibotors are also known was ______
Term
statins
Definition
drug class of choice for hyperlipidemia
Term
HBG-CoA Reductase
Definition
an enzyme which is a catalyst for making cholestrol. Statins inhibit its synthesis and promotes breakdown of cholestrol
Term
rhabdomyolysis
Definition
skeletal muscle disease which causes a breakdown of myoglobin
Term
HMG-CoA Reductase Inhibitors (Statins)
Definition
Rhabdomyolysis with renal failure is an adverse effect of ___________
Term
atorvastatin (lipitor)
Definition
preferred HMG-CoA Reductase Inhibotor (statin) that may be taken with or without food
Term
cholestyramine (Questran)
Definition
preferred bile acid binding agent
- needs to be taken with large amounts of fluid
Term
gemfibrozil (Lopid)
Definition
preferred fabric acid agent
- take 30 min before morning and evening meals
Term
X
Definition
statins are preg category ___
Term
Statins - bile acid sequesteraces
Definition
two antihyperlipidemics that may be combined for better results
Term
evening
Definition
statins are sometimes take in the _____ due to liver function
Term
nausea
Definition
statins may cause _____ (take with food)
Term
bile acid binding agents
Definition
medications that bind to bile acids to form insoluble substance that is not absorbed by the intestines - secreted by feces
Term
bile acid binding agents
Definition
medication that makes liver use cholestrol already in body to manufacture bile cause decrease in cholestrol levels
Term
bile acid binding agents
Definition
antihyperlipidemics that cause burnt odor to urine, constipation, GI cramping, flatulence, increased bleeding tendancy
Term
questran
Definition
bile acid binding agent that is also used to treat diarrhea
Term
bile acid binding agents
Definition
antihyperlipidemics that must be administered alone
Term
cholestyramine powder
Definition
bile acid binding agent that is mixed with 2 oz water or juice
Term
colestipol granules
Definition
bile acid binding agent that is mixed w/ 90 ml of fluid but does not dissolve
Term
fibric acid agents
Definition
antihyperlipidemics that were used the past but were mostly replaced by statins
- now used in combination with statins
Term
Tricor (Fenofibrate)
Definition
fibric acid agent that acts to reduce LDL and stimulates catabolism of triglycerides
Term
Lopid (gemfibrozil)
Definition
fibric acid agent that increases excretion of cholestrol in feces and reduces production of triglycerides
Term
fibric acid agents
Definition
antihyperlipidemic that is used to treat those with high serum triglycerides, prevent coronary heart disease, reducing LDL, and total cholesterol
Term
fibric acid agents
Definition
antihyperlipidemics that cause cholelithiasis(gall stones) and cholecystitis (inflammation of gallbladder)
Term
fibric acid agent
Definition
clofribrate
Term
niacin
Definition
medication that lowers blood lipid levels but requires no prescription
Term
325 mg ASA
Definition
dr may prescribe ___ to be given 30 min before Niacin to reduce flushing
Term
zetia
Definition
misc antihyperlipidemic that works in intestinal lining to inhibit absorption of cholestrol
- does not inhibit cholestrol synthesis in liver
Term
zetia
Definition
antihyperlipidemic that may cause back pain, arthalgia(joint pain), angioedema, sore throat, sinusitis, cough, rash, rhabdomyolysis
Term
vytorin
Definition
zetia + zocor
Term
advicor
Definition
mevicor(statin) and niacin
Term
caduet
Definition
Lipitor + Norivasc
Term
garlic - flax - guggul extract
Definition
three herbs used to lower cholestrol and triglycerides
Term
600-900 mg
Definition
recommended daily dose of garlic in order for it to be effective
Term
guggul extract
Definition
herbal used to increase HDL, lower LDL, lower trig
- relaxes muscle to relieve menstrual pain
Term
angina
Definition
result of artherosclerotic plaques form in coronary arteries, decreasing blood flow and O2 supply to the heart muscle
Term
antianginal meds
Definition
relieve chest pain by dilating lumen of arteries and increasing blood supply to myocardium
Term
nitrates
Definition
drugs that treat angina by relaxing the smooth muscle of coronary blood vessels
Term
headache
Definition
nitrates can cause a sever and persistant _______
Term
nitrates
Definition
drugs that can not be used in people with tape allergies
Term
viagra
Definition
nitrates can not be taken w/in 24 hours of _____ = severe hypotension
Term
diltiazem (Cardizam)
Definition
preferred med for angina and AMI
- dialates coronary arteries and decreases coronary artery spasms
Term
Ca channel blockers
Definition
drugs that should not be combined with grapefruit juice
Term
atenolo (Tenormin)
Definition
preferred Beta blocker for angina and AMI
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