- Inhibits microtubule formation by binding to tubuline; inhibition of microtubule assembly interrupts cellular motility for neutrolphil-mediated inflammatory reaction

- acute gout and prevention of recurrent gout attacks

- Myelosuppression, neuromyopathy

- Inhibition of xanthine oxidase, the enzyme that converts hypoxanthine and xanthine to uric acid; decreased uric acid levels lead to less urate crystal formation

- chronic gout, prevention of recurrent gout, cancer-related hyperuricemia, Ca2+ and uric acid renal calculus

- Do not use with aspirin

- increase levels of 6-MP

- Non-purine small-molecule inhibitor of xanthine oxidase

- Prevention of recurrent gout attacks

- Check liver enzymes

- when starting it you gotta give a suppressive gout med to reduce risk of flares for first few months

- inhibit renal tubule basolateral anion exchanger, leading to increased excretion of uric acid

- increase levels of penicilllin

- chronic gout and prevention of gout

- could give you uric acid kidney stones

- Is an angiotensin II receptor antagonist with modest uricosuric effect

- Hypertension and prevention of recurrent gout attacks

- don't take this if you're preggers

- Is a recombinant form of Aspergillus uricase that converts sparingly soluble urate to the more soluble allantoin

- Tumor lysis synd.

- Treatment of gout that is unresponsive to standard therapies

- contraindicated if a Glucose-6-phosphate dehydrogenase deficiency is present