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Pharm 2 midterm2
2nd midterm of Pharm 2
47
Nursing
Undergraduate 2
05/09/2012

Additional Nursing Flashcards

 


 

Cards

Term
Specific Rx the elderly should avoid
Definition
Amitriptyline (Elavil) Diphenhydramine (Benadryl) Clonidine (Catapres) flurazepam (Dalmane) carisoprodol (Soma) hydroxyzine (Vistaril)
Term
Distribution in Elderly
Definition

increased body fat (reduction in responses)

 

decreased lean body mass (increases effects of RX)

 

decreased total body water (increases effects of RX)

 

reduced serum albumin (increases effects of RX)

Term
Mood Stabilizers Antiepileptic Medications for BPD
Definition

Valproic Acid (Depakote)50-125mcg/ml

Carbamazepine (Tegretol)8-12g/ml

Lamotrigine (Lamictal)

Term
Initial Treatment of Acute Mania Until Lithium Takes Effect
Definition

Antiphychotics 

Antipsychotic or benzodiazepine to prevent:

exhaustion coronory collapse and death

Term
First-line for mixed mania and rapid cycling (BPD)
Definition
Valproic Acid (Depakote)
Term
Lithium Drug Interactions
Definition

Diuretics

(loss of sodium leads to lithium toxicity)

 

NSAIDS

(Increases renal reabsorption of lithium = increases toxicity)

 

Anticholinergics

(cause urinary hesitancy which combines with lithiums polyuria and results in discomfort)

Term
Management of Otitis Media RX Prototype
Definition
Amoxicillin for 5-10 days
Term
Rx for Psoriasis
Definition

Mild topical glucocorticoids- Calcipotriene (Dovonex) (derivative of Vit. D)

 

Moderate- methotraxate (Trexall)-PO-systemic

 

Moderate-Severe- Alefacept (Amevive)-IM Tcell antagonist

Term
Oral management for ACNE
Definition

Antibiotics:  doxycycline (Vibramycin)

 

Retinoid: Isotretinoin (Accutane) given for severe acne

 

 

Term
Topical management for ACNE Catagories
Definition

Antibiotics, Benzoyl Peroxide-mild to moderate

Retinoids-mild to moderate Tretinoin (Retin-A)

Retinoid- Severe- Accutane

Term
Topical Retinoid management for Mild to Moderate ACNE 
Definition
Tretinoin (Retin-A) Mild to Moderate ACNE
Term
RX management of Warts
Definition

Podofilox (Condylox)

 

Podophyllin (Podocon -25)

Term
Agents used for Atopic Dermatitis (Eczema)
Definition
1. skin moisturizers and glucocorticoids
2. immunosuppressants
topical-Tacrolimus (Protopic)
systemic-(Methotrexate)
Term
Actinic Keratoses
Definition
fluorouracil (Carac)
Disrupts DNA/RNA synthesis and is cytotoxic
Term
Rx for Glaucoma (4)
Definition

Prostaglandin Analogs-Latanoprost (Xalatan)

Alpha 2 Agonist-brimonidine (Alphagan)-Long Term

apraclonidine (lopidine)-Short Term

Beta Blocker-betaxolol (Betoptic) 

Term
Agents used to treat glaucoma
Definition

 prostaglandin analogs

Alpha 2 agnosts

Beta-blockers

Term
RX Management for conjunctivitis
Definition
Mast cell stabilizers
antihistamines
NSAIDs
glucocorticoids
Term
Classes of Chemotherapeutics
Definition
Cytotoxic
Hormone and hormone antagonists
Immuno-modulating agents
Targeted drugs for specific types of cancer
Term
Agents for dystonia and akathisia
Definition
Antiparkinsonian drugs:
benztropine mesylate (Cogentin)
amantadine (Symmetrel)
Term
2nd generation atypical antipsychotics
Definition
clozapine (Clozaril)
only used for schizophrenia
serisous SE
Term
2nd generation Atypical Antipsychotics (5)
Definition

Clozapine (Clozaril)

 

Paliperidone (Invega)

Risperidone (Risperdal)

Olanzapine (Zyprexa)

Quetiapine (Seroquel)

Term
Prototypes of FGAs`
Definition
Haloperidol (Haldol) - High potentcy
Loxapine (Loxitane) - Medium potency
Chlorpromazine (Thorazine) - Low potency
Haloperidol Decanoate (Haldol Decaoate)- Long acting aka Depot Antipsychotics
Term
High potency FGA
Definition
Haloperidol (Haldol)
Term
Medium potency FGA
Definition
Loxapine (Loxitane)
Term
Low potency FGA
Definition
Chlorpromazine (Thorazine)
Term
Long acting FGA aka Depot Antipsychotics
Definition
Haloperidol Decanoate (Haldol Decaoate)
Term
Types of Antidepressants
Definition
Tricyclic antidepressants (TCAs)
Amitriptyline (Elavil)
Imipramine (Tofranil)
Selective serotonin reuptake inhibitors (SSRIs)
Fluoxazid (Prozac)
Monoxamine oxidase inhibitors (MAOIs)
Isocarboxazid (Marplan)
Term
Tricyclic antidepressants (TCAs)
Definition
Amitriptyline (Elavil)
Imipramine (Tofranil)
Term
Selective serotonin reuptake inhibitors (SSRIs)
Definition
Fluoxazid (Prozac)
Term
Monoxamine oxidase inhibitors (MAOIs)
Definition
Isocarboxazid (Marplan)
Term
If Mrs. Javanovich were on Hospice, would she receive chemo- why or why not?
Definition
Yes, it is a palliative treatment
Term
If Mrs. Javanovich were to receive two chemos in conjunction with each other, what would the RN expect the primary reason is for that?
Definition

decrease of getting an intolerance,

Kill more of the cancer cells,

Kill less of the body cells

Term
What are some obstacles to chemo being effective?
Definition
1. Toxic to all cells
2. Early detection
3. Doesn't work well with solid tumors
4. Cancer cells can become resistant
5. Heterogenesis
6. Not able to target the cancers cells easily, can't penetrate to center of dense tumors
5
Term
What is the nadir? When does it occur?
Definition

Nadir is the trough/low point, it is the lowest point of bone marrow suppression,

 

Double check this answer!

Term
What is the MOA of betoptic?
Definition
For Glaucoma-lowers IOP by decreasing production of aqueous humor by blocking B1 receptors,
Term
 Many homeless people have untreated or undertreated mental illness. What would the RN consider to be the reason for erratic behavior in a homeless man, age 30, Caucasian, who is seen at the roadside talking to himself as if he is holding a conversation with an unseen person? Is this an example of a behavioral, physical, or cognitive s/s?
Definition
Cognitive-because he is responding to an hallucination
Term
What would be the reason for the same man seen several months later, after having received treatment, standing at the clinic with his tongue "lolling" about in his mouth?
Definition
Tardive Diskenesia
Term
A patient tells the NP that she stopped taking her Prozac 2 days ago because she had "no libido." She was on 40 mg daily. What is the immediate concern?
Definition
Withdrawal Syndrome
Term
3 Stages of Teratogenesis
Definition
Preimplantation/presomite period-conception-2weeks- =death or recovery
Embryonic Period- 3-8 weeks- =grose abnormalities
Fetal Period- 9weeks-fullterm- =function problems
Term
3 Critera for Rx teratogen
Definition
1. Acts during a specific time
2. Given set of malformations
3. abnorm. increase as dosage and duration of exposure does
Term
Rx for Meniere's
Definition
acyclovir (antiherpes) because it is thought to correlate with herpes simplex virus
Term
Rx For Otitis Externa
Definition
acetic acid (found in vinegar) mixed with alcohol
May require hydrocortisone or neomycin
Best Treatment- fluoroquinolones but expensive
Term
Rx for Fungal Otitis Externa
Definition
acetic acid and cleansing sol.
antifungal- clotrimazole (Lotrimin)
Term
Rx for Wet AMRD
Definition
ranibizumab (Lucentis)-Injection into eye Newest- aflibercept (Eylea)
Term
Dry ARMD Rx
Definition
Ocuvite PreserVision- antioxidants, zinc, Vit. C and E, Beta-Carotene, Copper
Term
SNRI
Definition

Prototype: Venlafaxine (Effecxor)-

Being researched-Levomilnacipran, milnacipran (Dalciprin)-

Term
What aminoacid interferes with MOAIs?
Definition
tyramine-in meats, cheeses, avocado, soy, beans
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