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Pharm 2 Final
New Drugs and Categories in Weeks 7-10
73
Nursing
Undergraduate 2
06/02/2012

Additional Nursing Flashcards

 


 

Cards

Term
Alzheimer's Disease: Types of agents for relief of Sx
Definition

(N-Methyl-D-aspartate) NMDA receptor antagonists

NSAIDS

 

Cholinesterase inhibitors

Atypical antipsychotics

Vitamin E and Selegiline

Estrogen

 

Ginkgo Biloba 

Term
Cholinesterase Inhibitors
Definition
Donepezil (Aricept)
Term
(N-Methyl-D-aspartate) NMDA receptor antagonists
Definition
Memantine (Namenda)
Term

Pharmacological Management: Agents Used for Parkinson's

Definition

Dopaminergic agents and Anticholinergics Angents


Dopaminergic agents-

Levodopa (L-DOPA) Levodopa/Carbidopa (e.g., Sinement, Paracopa)

Dopamine agonists [e.g., Pramipexole (Mirapex)]

COMT (Catechol-O-Methyltransferase) Inhibitors [(e.g., Entacapone (Comtan)]

MAO-B Inhibitors [(e.g., Selegiline (Eldepryl)]


Anticholinergics Angents-

trihexyphenidyl (Artane)

Term
Dopamine Agonists for Parkinson's Two Types
Definition

Ergot (an alkaloid found in plants) derivatives

bromocriptine, cabergoline

 

Nonergot derivatives

pramipexole (Mirapex), ropinirole

Term
COMT Inhibitors (Catechol-O-Methyltransferase)for Park.
Definition
Entacapone (Comtan):
Term
MAO-B Inhibitors for Park.
Definition
selegiline (Eldepryl)
Term
Anticholinergic Agents for Park.
Definition
trihexyphenidyl (Artane)
Term
Types of seizures and their types
Definition
Partial seizures (three types): simple partial seizures, complex partial seizures, and partial seizures

Generalized seizures: convulsive or nonconvulsive. Tonic-clonic seizures (Grand Mal) are often stereotypes of seizure activity. This type of generalized seizure is exemplified by a characteristic time of muscle rigidity (tonic), followed by a time of jerking muscles (clonic).
Term
Traditional Antiepileptic Agents
Definition

Primidone (Mysoline)

Carbamazepine (Tegretol)

Ethosuximide (Zarontin)

Phenobarbital

Phenytoin (Dilantin)

Valproic Acid (Depakene)  

Term
List of Newer Antiepileptic Agents: (13)
Definition
Oxycarbazepine (Trileptal)
Lamotrigine (Lamictal)
Gabapentin (Neurontin)
Pregabalin (Lyrica)
Levetiracetam (Keppra)
Topiramate (Topamax)
Tiagabine (Gabitril)
Zonisamide (Zonegran)
Felbamate (Felbatol)
Lacosamide (Vimpat)
Rufinamide (Banzel)
Vigabatrin (Sabril)
Ezogabine (Potiga)
Term
Classes of Antiulcer medications (5)
Definition
1.antibiotics 2.antacids 3.antisecretory agents 4.antisecretory agents that enhance mucosal defenses 5.mucosal protectants
Term
Nonpharmacological Management for Ulcers
Definition

frequent, smaller meals

 

Smoking cessation

 

Avoid ASA and NSAID administration

 

Alcohol consumption may aggravate Sx, and therefore reduce intake if it does cause increased Sx.

 

Decrease stress/anxiety

Term
Man. of Ulcers Triple therapies (3)
Definition
omeprazole (prilosec), amoxicillin, and clarithromycin for 10 days
bismuth subsalicylate, metronidazole, and tetracycline for 14 days
lansoprazole, amoxicillin, and clarithromycin, approved for either 10 or 14 days
Term
Antibiotics for Ulcers (5)
Definition
amoxicillin***, clarithromycin (Biaxin), tetracycline, metronidazole (Flagyl), and tinidazole (Tindamax)
Term
Histamine2 Receptor Antagonists (4)
Definition
cimetidine (Tagamet)***
ranitidine (Zantac),
famotidine (Pepcid),
nizatidine (Axid
Term
Proton Pump Inhibitors
Definition
omeprazole (Prilosec)
Term
Other Agents for Ulcers (2)
Definition
Sucralfate (Carafate)
Misoprostol (Cytotec)
Term
Antacids (4)
Definition

Magnesium hydroxide (AKA milk of magnesia)

Aluminum hydroxide

Sodium bicarbonate

Calcium carbonate 

Term
Anticholinergic Agent to Manage Ulcer
Definition
Pirenzepine (Gastrozepine):
Term
Types of Laxatives (4)
Definition

Bulk forming laxatives

Osmotic laxatives

Surfactant laxatives

Stimulant laxatives

 

Term
Bulk Forming Laxatives (3)
Definition
methylcellulose (Citrucel), psyllium (Metamucil), polycarbophil (FiberCon).
Term
Surfactant Laxatives
Definition
docusate sodium (Colace),
docusate calcium
Term
Stimulant Laxatives
Definition
Bisacodyl (Dulcolax).
Senna (Senokot):
Castor Oil
Term
Osmotic Laxatives
Definition
magnesium hydroxide (milk of magnesia)
sodium phosphate (Fleet Phospho-Soda)
polyethylene glycol (MiraLax):
Term
Other Laxatives
Definition

Glycerin suppository

Lactulose 

Lubiprostone (Amitiza)

Mineral oil 

Polyethylene Glycol-Electrolyte solutions (GoLYTELY)

Term
Vomiting Center triggers (5)
Definition
*CTZ
*cranial nerve X (vagus nerve)
*vestibular system (Look up)
*enteric nervous system
*CNS
Term
Types of Antiemetic Agents and Prototypes (7)
Definition

Antihistamines: dimenhydrinate (Dramamine)

Benzodiazepines: lorazepam (Ativan)

Cannabinoids: dronabinol (Marinol)  

Dopamine antagonists: metoclopramide (Reglan)

Serotonin Receptor Antagonists: Ondansetron (Zofran) Substance P/Neurokinin1 Antagonists: aprepitant (Emend)

Glucocorticoids: dexamethasone (Decadron) 

Term
Serotonin Receptor Antagonists for antiemetic
Definition
Ondansetron (Zofran).
Term
Glucocorticoids for antiemetic
Definition
dexamethasone (Decadron).
Term
Substance P/Neurokinin1 Antagonists
Definition
aprepitant (Emend).
Term
Benzodiazepines
Definition
lorazepam (Ativan).
Term
Dopamine Antagonists for antiemetic
Definition
metoclopramide (Reglan).
Term
Cannabinoids
Definition
dronabinol (Marinol)
Term
Three types of emesis as related to CINV
Definition
1.anticipatory: nausea created from thinking of
previous illness resulting in nausea
2.acute: nausea initiated with the administration of
chemotherapy and occurs within hours of taking
the medications
3.delayed: nausea that occurs after at least a day
after receiving the chemotherapy
Term
Qualm
Definition
“a sudden feeling of nausea, sickness, or faintness”
Term
Motion Sickness Agents (2)
Definition
Scopolamine:
Dimenhydrinate (Dramamine):
Term
Three types of Diarrhea
Definition
1.osmotic: something in the bowel is drawing water from the body into the bowel (e.g., sorbitol, a sugar substitute, is not absorbed by body, and draws water from body into bowel, resulting in diarrhea)

2.secretory: body releases water into bowel in pathology (e.g., infections)

3.exudative: refers to the presence of blood/exudate in the stool (e.g., ulcerative colitis)
Term
Two types of Antidiarrheal agents
Definition
specific antidiarrheals,
nonspecific antidiarrheals
Term
Nonspecific Antidiarrheal Medications
Definition
Opiods: Diphenoxylate (Lomotil); Loperamide (Imodium)
Term
Vasoconstrictor Used with Local Anesthetics
Definition
epinephrine
Term
Topical Anesthetics (4)
Definition

Benzocaine

Lidocaine Patch

Alcaine (Proparacaine)

Cocaine

 

 

Term
Parenteral Local Anesthetics
Definition
Procaine (Novocain)
Lidocaine
Term
Regional (Local) Anesthetics
Infiltration (3)
Nerve block (2)
Definition
Infiltration- Novocain,Lidocaine,Bupivacaine (Marcaine)
Nerve Block:
Lidocaine,Bupivacaine (Marcaine)
Term
Definition of MAC
Definition
Minimum (or median) alveolar concentration
an index of inhaled anesthetic potency
Term
Inhaled Anesthetics 2 Types
Definition

Gases: nitrous oxide

 

Volatile liquids:

halothane, isoflurane, desflurane, enflurane, sevoflurane.

Term
Goals of Inhalation Anesthesia (4)
Definition
Produces unconsciousness & analgesia

Easy induction period

Pleasant after effects

Can control levels easily
Term
Adjunctive Anesthesia Drugs (4 Catagories w/ proto.)
Definition

Benzodiazepines

 

Opiates

 

Alpha2-Adrenergic Agonists:

Clonidine (Duraclon), Dexmedetomidine (Precedex)

 

Anticholinergics:

atropine

Term
Neuromuscular Blocking Agents (NMBAs):
2 Types
Definition
Depolarizing: Succinylcholine
Non-depolarizing: Atracurium (Tracrium)

Tubocurarine (oldest)
Term
Inhaled Anesthetic (2)
Definition
Halothane (Fluothane)

Nitrous Oxide
Term
Intravenous Anesthetic Agents (3 cat. or their proto.)
Definition
Short acting barbiturates:
Thiopental (Pentothal)
Benzodiazepines:
Diazepam (Valium)
Sedative/hypnotic
Propofol (Diprivan)***
Term
Most reliable birth control (4)
Definition
sterilization, IUDs, depo-Provera, Implanon
Term
Least reliable birth control (4)
Definition
periodic abstinence, spermicides, barrier methods, withdrawal
Term
Middle tier of reliable birth control: (3)
Definition
oral contraceptives, contraceptive ring, contraceptive patch
Term
Choice of Birth Control
Definition
Sterilization (e.g., tubal ligation, vasectomy)

Oral contraceptives or condoms chosen next

“Other”: diaphragms, periodic abstinence, and IUDs (which recently are “on the rise”)
Term
Oral Contraceptive classes (2)
Definition
1.combination oral contraceptives (COC),
2.progestin-only oral contraceptives (e.g., “mini-pill”).
Term
Newer Combined Oral Contraceptives (COCs)
Definition
Drospirenone/Ethinyl Estradiol (YAZ) (24 active days & 4 placebo days).
Levonorgestrel/Ethinyl Estrodial (Seasonale) (84
active days & 7 placebo days)
Term
Agents that Reduce the Effects of Oral Contraceptives (6)
Definition
Rifampin
Ritonavir
Antiepileptics (i.e., phenytoin, primidone, phenobarbital, carbamazepine)
St.John’s wort (herbal)
Warfarin (Coumadin)
Hypoglycemics
Term
Agents Whose Effects are Increased by Oral Contraceptives
Definition
Tricyclic antidepressants
Diazepam (Valium)
Chlordiazepoxide (Librium)
Theophylline (Aerolate III)
Term
Progestin-only contraceptives
Definition

Mini-pill

Implanon

Term
Combination Contraceptives Using Unique Methods of Delivery
Definition
NuvaRing (vaginal contraceptive ring)
Transdermal Patch
Term
Long-Acting Contraceptives
Definition
Implanon (etonogestrel implant) (NEXPLANON)
Depot Medroxyprogesterone Acetate (DMPA):
IM (Depo-Provera) SQ (Depo-subQ)
Term
Intrauterine Devices
Definition
copper T 380A (ParaGard)
(Mirena- a hormone containing device that releases progestogen
Term
Barrier Devices
Definition
Condoms
Diaphragm
Cervical cap
Term
Agents Used for Medical Abortion
Definition
Mifepristone (RU 486)
Term
Emergency Contraception (EC)
Definition
emergency contraceptives or “morning after pill”; Plan B; Copper IUD
Term
Two types of Emergency Contraception Pills:
Definition
1.emergency contraceptive pill (ECP), and 2.Yuzpe regimen
Term
Menstrual Cycle Phases
Definition
Menstruation phase (approximately days 1-4)
*FSH stimulates follicles to develop  estrogen

Follicular phase (approximately days 1-14)
*Estrogen secretion continues 

Ovulation phase (approximately days 13-16)
*Ovum is released (note: this time of “fertility” is 24-48
hours)

Luteal phase (approximately days 16-28)
*Corpus luteum produces progesterone & estrogen
Term
Estrogen
Definition
Estrogens (estradiol)
Term
Selective Estrogen Receptor Modulators (SERMs)
Definition
tamoxifen (Nolvadex)
Term
Menopause Hormone Replacement Therapy (HRT)
Definition

Oral Preparations:

Women with a uterus – Prempro

Hysterectomy – Premarin (estrogen)


Intravaginal:

Estradiol (Estrace)

 

 

Bio-identical hormone replacement therapy (BHRT)

Term
Preventing Osteoporosis: Supplements (3)
Definition

Calcium carbonate (Alka-Mints) – most common

Calcium citrate  

Vitamin D

Term
Preventing Osteoporosis: Drugs
Definition
Bisphosphonates (e.g., Actonel) – inhibits bone resorption
SERMs – Raloxifene (Evista)
Forteo (Teriparatide)– parathyroid hormone derivative
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