Term
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Definition
| the subset of actions normally produced by endogenous acetylcholine on nicotinic receptors that can also be produced by exogenous nicotine |
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Term
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Definition
| the effect that resembles the postganglionic parasympathetic receptor stimulation by acetylcholine; an effect that resembles the muscarinic effect can be caused by exogenous muscarine, pilocarpine, arecoline, and physostigmine |
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Term
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Definition
| Related to effects on nerve cells or fibers in the sympathetic nervous system that use norepinephrine as their neurotransmitter. An effect that resembles the adrenergic effect can be produced by exogenous ephedrine or cocaine |
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Term
| Nicotinic Receptors in Autonomic Ganglio |
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Definition
-Nicotine stimulates receptors and, in very high doses, blocks receptors
-D-tubocurarine blocks these receptors |
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Term
| Nicotinic Somatic Motor Receptors in Striated Muscle |
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Definition
| D-tubocurarine, toxiferine, and botox have antagonistic effects on somatic motor nicotinic receptors resulting in the blockage of receptors causing muscle paralysis |
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Term
| Adrenergic Receptors of the Sympathetic Nervous System |
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Definition
-ephedrine stimulates these receptors
-cocaine increases levels of norepinephrine at these receptors |
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Term
| Muscarinic Receptors of Parasympathetic Nervous System |
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Definition
Cholinomimetic/Parasympathomimetic Effects
- muscarine, pilocarpine, and arecoline stimulates muscarinic receptors
-physostigmine inhibits acetylcholinesterase, the enzyme that breaks down acetylcholine, which results in an increase of acetylcholine in the synaptic cleft of the receptor
Anticholinergic Effects
-atropine and scopolamine block the muscarinic receptors preventing the action of acetylcholine; this results in a dominance of the sympathetic nervous system |
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