Term
| Prolonged storage of blood in EDTA tubes causes what RBC morphologic abnormalities? |
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Definition
1. Loss of central pallor - false spherocytosis 2. Echinocytosis 3. Excessive lymphocytic nuclear lobulation
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Term
List 4 causes of inherited microcytosis
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Definition
1. Thalassemias & Hemoglobinopathies
2. Atransferrinemia 3. Congenital sideroblastic anemia 4. Copper deficiency
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Term
List 4 causes of acquired microcytosis
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Definition
1. Iron deficiency 2. MDS 3. Hyperthyroidism 4. Anemia of chronic disease
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Term
In what two states can you encounter macrocytes as a normal physiologic process?
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Definition
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Term
What infectious agent causing sepsis also is associated with microcytosis?
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Definition
1. Clostridium perfringens
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Term
Name three conditions resulting in acquired
echinocytosis |
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Definition
1. Liver disease 2. Uremic Syndrome 3. After a burn
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Term
Name 4 conditions associated with acanthocytosis
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Definition
1. abetalipoproteinemia 2. chronic liver disease 3. McLeod phenotype 4. Vit E deficiency in neonates
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Term
What components make up the following red blood cell inclusions? Howell-Jolley Basophilic stippling Pappenhemier bodies |
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Definition
1. HJ = DNA 2. Basophilic stippling = RNA 3. Paps = ferritin aggregates
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Term
Slender, radially oriented crystals in reticulocytes can be seen in what congenital condition?
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Definition
Congenital erythropoietic porphyria
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Term
[image] [image] What is this cell associated with? |
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Definition
This is an 'LE-cell' that is associated with systemic lupus erythematosus. The inclusion is DNA/histone complexes ingested by neutrophils
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