Term
health gingivitis periodontitis |
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Definition
Basic states of the periodontium |
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irreversible tissue damage |
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PD progression is slow and constant until tooth loss, severity of disease increases with age |
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PD progresses in short bursts of exacerbation (actively losing attachment) followed by a period of remission where there is no progressive attachment loss |
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PD activity occurs during a limited time period followed by remission |
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Asynchronous multiple burst theory |
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all model theories of disease activity |
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explain disease progression |
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that all sites will continuously get worse |
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treatment (?) until a burst of bone destruction has occurred |
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determine which site is active |
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periodontitis does not develop unless |
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gingivitis existed previously |
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does gingivitis ALWAYS progress to periodontitis? |
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Definition
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bacteria that colonize first on tooth surface at gingival margin are: |
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Definition
Supragingival gram-positive facultative Streptococci and Actinomyces secies |
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a foreign substance that elicits the formation of antibodies |
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host cells such as (?) can secrete collagenase |
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if the body is overwhelmed |
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host response can be destructive, causing hard and soft tissue destruction |
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1st attempt at self protection come from |
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Definition
supragingival environment |
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contains defensive substances such as antibacterial factors and antibodies |
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proteins present in blood serumand mucosal secretions produced following interaction with an antigen |
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fluid that flows into the sulcus from the adjacent gingival connective tissue |
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Definition
gingival crevicular fluid |
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Term
gingival crevicular fluid are |
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Definition
the 1st substances to interact with bacteria to try to neutralize, isolate or kill it |
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endotoxins exotoxins enzymes |
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saliva gingival crevicular fluid oral epithelium shedding of epithelial cells |
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Collagenase Hyaluronidase Proteases |
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the immune response is further stimulated to eliminate antigens and prevent spread of infection when |
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Definition
the body is unsuccessful in eliminating pathogenic bacteria at supragingival level |
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Term
Elimination and retardation of antigen Limiting of further tissue destruction Beginning of healing |
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Definition
result of the activation of inflammatory/immune response |
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Term
Polymorphonuclear Leukocytes (PMNs) Monocytes/Macrophages |
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proteins that are involved in regulating the activity of the cells that release them, as well as other cells |
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Cytokines (interleukin 1) |
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primary substance responsible for vasodilation and increased permeability of the blood vessel wall. |
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Histamines are released from? |
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mast cells found in connective tissue |
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fatty acids also involved in vasodilation and responsible for pain and bone loss in periodontal disease |
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Definition
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vasodilation as a result of prostagladin activity clinically appears as |
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cells that form a protective wall between bacteria and lining of gingival sulcus |
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which type of cell is primarily recruited in high numbers to the site of acute inflammation? |
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Which cell is phagocytic? |
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Which cell is mainly involved in the body's immune response to invading bacteria? |
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Definition
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Term
Periodontal diseases are considered a group of infections characterized by destruction of the periodontium. The direct effects of the bacteria and indirect effects by the body's own immune response are primarily responsible for the destruction. |
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the first attempt at self protection comes from which area in the oral cavity? |
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Definition
Supragingival environment |
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Which cell can contribute to periodontal bone resorption? |
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Which cell is responsible for "patrolling" the body? |
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Which cell is involved in regulating the activity of other cells? |
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Which substance is released from all gram-negative bacteria and cause damage to the periodontium? |
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Which of the following are theories of periodontal disease activity? Continuous burst Random burst Asynchronous, multiple burst All |
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