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Peptic Ulcer Disease (PUD)
Peptic Ulcer Disesae (PUD) Background
9
Pharmacology
Professional
08/29/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
What is a peptic ulcer
Definition

a mucosal erosion within the gastrointestinal tract, most ulcers occur in the duodenum but a small percent do occur in the stomach

Term
H. pylori and peptic ulcers
Definition

Helicobacter pylori (H. pylori), a spiral - shaped bacterium that lives in the acidic environment of the stomach, is responsible for most of the peptic ulcers (~70 - 80%).

 

Term
What common drugs can cause or worsen peptic ulcers?
Definition

caused or worsened by aspirin or nonsteroidal antiinflammatory drugs (NSAIDs).

 

Term
What syndrome can cause peptic ulcers?
Definition

Zollinger - Ellison syndrome (causes increased gastric acid)

Term
Primary symptoms of PUD
Definition

epigastric pain; epigastric refers to the upper region of the abdomen, this pain is associated with a burning or gnawing sensation and may awaken a patient if it occurs at night.

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Term
What can be done to relieve the pain of duodenal ulcers?
Definition

If the ulcer is duodenal (usually cased by H. pylori), eating lessens the pain.

Term
Does eating help with gastric ulcers?
Definition

With gatric ulcers, eating worsens the pain.

 

Term
H. pyloir infection, if allowed to continue long - term, can lead to what?
Definition
cancer
Term
What common tests can be used to test for H. pylori?
Definition

(1) urea breath test

(2) stool antigen test

(3) Blood (serologic) test

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