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Pentose Phosphate Pathway
PPP -Roth
10
Medical
Professional
08/05/2009

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Cards

Term
steps 1-3 (oxidative steps)
glucose 6 phosphate dehydrogenase
Definition
step 1: Rate limiting) Glucose 6P --> 6-phosphogluconolactone + NADPH
Term
steps 1-3 (oxidative steps)
lactonase
Definition
step 2) 6-phosphogluconolactone --> 6-phosphogluconate
Term
steps 1-3 (oxidative steps)
6-phosphogluconate dehydrogenase
Definition
step 3: 6-phosphogluconate --> ribulose 5P + CO2 + NADPH
Term
Stoichiometry reaction for oxidative steps of PPP
Definition
steps 1-3) glucose 6P + 2 NADP° +H2) --> ribulose 5P + CO2 + 2 NADPH + H°
Term
steps 4-8 (non-oxidative steps)
pentose phosphate isomerase
Definition
step 4) ribulose 5P --> ribose 5P
Term
steps 4-8 (non-oxidative steps)
pentose phosphate epimerase
Definition
step 5) 2 (ribulose 5P) --> 2 (xylulose 5P)
Term
steps 4-8 (non-oxidative steps)
transketonase-TPP
Definition
step 6) ribose 5P + xylulose 5P --> glyceraldehyde 3P + sedoheptulose 7P
Term
steps 4-8 (non-oxidative steps)
transaldolase
Definition
step 7) glyceraldehyde 3P + sedoheptulose 7P --> Fructose 6P + erythrose 4P
Term
steps 4-8 (non-oxidative steps)
transketonase -TPP
Definition
step 8) Erythrose 4P + Xylulose 5P --> glyceraldehyde 3P + Fructose 6P
Term
Stoichiometry reaction for non-oxidative steps of PPP
Definition
steps 4-8) 3 (Ribulose 5P) --> glyceraldehyde 3P + 2(fructose 6P)
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