Term
MOA of Penicillins (PCNs) |
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Definition
Beta-lactams that inhibit bacterial cell wall synthesis by binding to one or more pencillin-binding proteins (PBPs) thus inhibiting final step in bacterial cell wall synthesis. |
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Term
Concentration dependent or time dependent? |
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Definition
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Term
Brand name for Amoxicillin |
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Definition
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Term
Brand name for Amoxicillin + Clavulanate |
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Definition
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Term
What does the clavulanate do? |
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Definition
Used to combat antibiotic resistance. Certain bacteria secret beta-lactamase which inactivates penicillins.
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Term
Amoxicillin is mostly active against what? |
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Definition
Gram positive cocci (staph and strep) and some gram negative.
no atypical coverage.
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Term
Amoxicillin is the DOC for what? |
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Definition
acute otitis media
H pylori regimen
pregnancy
prophylaxis for endocarditis |
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Term
Name two possible serious side effects? |
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Definition
Agranulocytosis (severly lowered white blood cell count)
Increased LFTs |
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Term
Pregnancy category of Amoxicillin |
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Definition
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Term
Brand name for Ampicillin |
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Definition
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Term
Brand name for Ampicillin + sulbactam |
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Definition
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Term
Brand name for Penicillin |
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Definition
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Term
Brand name for Piperacillin + tazobactam |
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Definition
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Term
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Definition
Used to combat bacteria that secrete beta-lactamase that would otherwise render pipericilling inactive.
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Term
What does the sulbactam do? |
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Definition
Beta-lactamase inhibitor. Used to combat bacteria that secrete beta-lactamases that would otherwise render ampicillin inactive.
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Term
Should Augmentin be refrigerated or not? |
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Definition
Yes. Must be refrigerated. |
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Term
Should Amoxil oral suspension be refrigerated or not? |
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Definition
May be refrigerated to improve taste. |
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Term
When should Moxatag be taken? |
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Definition
Within one hour of finishing a meal. |
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Term
Should Pen VK be refrigerated or not? |
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Definition
Yes. Must be refrigerated. |
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Term
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Definition
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Term
Reduce dose in renal impairment for all PCNs except for? |
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Definition
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Term
Brand name for Ticarcillin + clavulanic acid? |
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Definition
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Term
Brand name for Ticarcillin? |
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Definition
None. It isn't formulated by istself. Always formulated with clavulanic acid. |
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Term
Uricosuric agents such as probenecid and allopurinol do what to the levels of PCNs? |
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Definition
Increase
Note: uricosuric = increase urine acid excretion |
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Term
PCNs may do what to oral contraceptives? |
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Definition
Decrease effectiveness of oral contraceptives - check package insert for individual drug. |
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