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Penicillin and cephalosporins
test 2
21
Pharmacology
Undergraduate 3
06/20/2012

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Cards

Term
tetracycline
Definition
bacteriostatic
Term
penicillin
Definition
bactericidal
Term
four mechanisms of action of antibacterial drugs
Definition
inhibit cell wall synthesis
alter cell wall permeability
inhibit protein synthesis
interfere with metabolism of cell
Term
antibacterials with longer half life
Definition
maintain greater concentration at binding site
Term
bacterial resistance
Definition
natural or acquired
Term
hospital acquired infection
Definition
nosocomial
Term
3 major adverse effects related to antibacterial drugs
Definition
organ toxicity
hypersensitivity
superinfection
Term
minimum effective concentration depends on
Definition
absorption, metabolism, distribution, excretion
Term
4 factors related to host defense mechanisms
Definition
age,wbc, organ function, immunoglobulins
Term
6 nursing interventions related to administration of penicillin
Definition
allergies, superinfection, body temperature, c&s, dilute for iv use
Term
4 areas for teaching pts taking penicillin
Definition
id bracelet of allergy to, increase fluids, take all meds, take with foods.
Term
cephalosporisn administered
Definition
IV or IM
Term
superinfection
Definition
normal flora disturbed
Term
drug interaction with cephalosporin
Definition
alcohol
Term
Aztreonam effective against
Definition
Haemophilus influenzae
Term
Probenecid administered with cefazolin(ancef) or cefamandole (mandol)
Definition
drug action is increased
Term
Keflex
Definition
q6h, 200-500mgq6h, uricosurics change action of , taking total amt of prescribed, resting, aler for signs and symptoms of superinfection
Term
Cephalosporin side effects
Definition
nausea, vomiting, diarrhea, itching
Term
broad spectrum pen may decrease effectiveness of
Definition
oral contraceptives
Term
substitute for penicillin
Definition
erythromycin
Term
Quinupristin/dalfopristin (synercid)
Definition
vancomycin-resistant entercoccus faecium
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