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Peds Hematemesis
KYCOM Block 11
49
Medical
Graduate
10/25/2013

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Cards

Term
define hematemesis
Definition
emesis of bright red (large bleed) or coffee ground vomit
Term
define emesis
Definition
vomiting
Term
what are 3 suprious causes of GI bleeding
Definition
food: jello, kool aid, tomato, beet, cranberries
amoxicillin
nasopharyngeal source
Term
how can you determine if a bleed is a true bleed (3)
Definition
NG tube and gastric lavage
gastro-occult
hemoccult
Term
how does a NG tuve and gastric lavage work
Definition
put NG tuve into stomach, wash it out, and aspirate to see if there is a bleed
Term
how does a hemoccult work
Definition
sees if there is blood in the stool to determine presence of a bleed
testing abilities are limited in emesis
Term
what is the best way to determine location of a bleed, why
Definition
endoscopy
old contrast radiology method does not identify mucosal bleeds
Term
define mallory weiss tear
Definition
spontaneous tear at gastro-esophageal junction after forced emesis
Term
how does a parent normally explain the symptoms of a mallory weiss tear
Definition
the vomiting was initially normal yellow and now is full of blood
Term
what are three locations of a mallory weiss tear and their frequencies
Definition
usually extend into gastric side causing most bleeding
20% extend into esophagus
20% have multiple tears
Term
how is a mallory weiss tear treated (3)
Definition
self limited in kids
anti-emetics
stomach decompression
Term
what are three ways to treat a mallory weiss tear if no other methods work
Definition
electrocoagulation
surgery
fel foam embolization of lt gastric artery
Term
what are two other ways to say GERD
Definition
reflux esophagitis
acid reflux
Term
who normally gets GERD
Definition
teens
Term
what are two complications or associations with GERD
Definition
progression to major hemorrhage
hiatial hernia
Term
what is the major acid barrier to GERD
Definition
LES
Term
describe the LES
Definition
3-4 CM long smooth muscle with intrinsic and extrinsic pressure and tonic contraction
Term
what causes the extrinsic pressure on the LES (4)
Definition
crus of diaphragm
intra abdominal location
integrity of phreno-esophageal ligament
maintience of acute angle of His
Term
what mechanism causes GERD
Definition
decrease in LES pressure allows acid into esophagus
Term
what are 4 foods that decreases LES pressure
Definition
fat, chocolate, ethanol, peppermint
Term
what are 6 GI signalers that decrease LES
Definition
secretin
CCK
glucagon
somatostatin
GIP
VIP
Term
what are 4 hormones or neurotransmitters that decrease LES
Definition
progesterone
prostaglandins
serotonin
dopamine
Term
what are 3 drugs that decrease LES
Definition
morphine
diazepam
barbituates
Term
if stimulated (or antagonized) what receptors would decrease LES (3)
Definition
a antagonist
B agonist
cholinergic antagonist
Term
if stimulated (or antagonized) what receptors would increase LES (3)
Definition
a agonist
B antagonist
cholinergic agonist
Term
what food increases LES
Definition
protein
Term
what drugs increase LES (4)
Definition
antacids
metoclopramide
domperidone
cisapride
Term
what substances naturally made in the body increase LES 95)
Definition
gastrin
motilin
substance P
prostaglandin
histamine
Term
why is GERD worse at night (5)
Definition
during sleep there is less LES tone
you are layind down so gravity isnt helping
you are at rest and digest mode
dry swallow stops so peristalsis pushing acid down stops
less saliva production so less alkaline buffer
Term
what are the symptoms of GERD dependent on
Definition
extent of esophageal and mucosal injury
Term
what two things can increase GERD symptoms
Definition
acid reflux
potency of refluxate
Term
what are 5 complications of GERD
Definition
erosive esophagitis
sentineal fold
barrett's esophagus
reflux stricture
hiatial hernia
Term
what is barrett's esophagus, how is it identified
Definition
pre-cancerous metaplasia of lower esophageal mucosa with tongue like projections

has goblet and columnar cells (abnormal)
Term
how is GERD diagnosed, what are the first two and last two steps
Definition
barium swallow first
esophageal pH studies second
endoscopy
manometry
Term
what is the treatment for GERD (5)
Definition
antacids
H2 receptor antagonist
protein pump inhibitor
pro-kinetic agent
carafate
Term
define erosive gastropathy
Definition
subepithelial hemorrhage or erosion
Term
what is erosive gastropathy associated with
Definition
histological gastritis
Term
what are 5 causes of erosive gastropathy
Definition
NSAIDS
stress; burns, sepsis
prophylactic acid supression in ICU
alcohol
H. pylori
Term
how can you tell if someone has NSAID erosive gastropathytis
Definition
flea bitten appearance on endoscopy
Term
how can you tell if someone has H. pylori erosive gastropathy (4)
Definition
pink nodules
prominent gastric rugae
shows on gemisa stain
gram negative pleonprphhic comma shaped rods in lumen
Term
how is erosive gastropathy diagnosed
Definition
endoscopy
Term
how is erosive gastropathy treated (6)
Definition
pin point etiology
anti-helobacter
acid supression: antacid, H2 receptor antagonist, proton pump inhibitor
rare: volume expanders, electrocoagulation
Term
whais a esophageal varices or portal gastropathy
Definition
massive hemorrhage
Term
what causes esophageal varices (2)
Definition
chronic liver disease
cystic fibrosis
Term
what are 4 signs of esophageal varices
Definition
splenomeagly
acetes
abnormal LFT
portal gastropathy looks red with spider webs on endoscopy
Term
how is esophageal varices treaed (7)
Definition
volume resuscitation: prompt
vasopressin
somatostatin
TIPS
surgical porto caval shunt
liver transplant
viscereal scleropathy
Term
what is visceral scleropathy
Definition
injecting sclerosing agent to induce fibrosis to stop bleeding
Term
gastric and duodenal ulcers: who gets it, what are two causes
Definition
rare in childhood

H. pylori, hypergastrinemia
Term
how are gastric and duodenal ulcers treated (6)
Definition
stop bleed: thermocoagulation, epinepherine
acid supression: proton pump inhibitor, H2 receptor antagonist
carafate: promote healing
anti-helobacter
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