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Pediatrics APC II
Review of Critical Info in APC Lecture
84
Medical
Post-Graduate
02/20/2011

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Cards

Term
Fever
Definition
Rectal Temp > 100.4
Oral or Tempanic > 99.6
Term

Role of Dispensing Pharmacist

1. Check

2. Demonstrate

3. Consider

4. Label

Definition
Check all doses for pediatric patients
Demonstrate how to measure and administer doses for Rx and OTC Meds
Consdier child's taste preferences
Label scripts for young children with Give not Take
Term
Low Grade Fever
Definition
below 101.5F
Term
High grade fever
Definition
Above or equal to 101.5 F
Term
Hypothalamus
Definition
Endogenous pyrogens increase set point here
Term
Shivering increases
Definition
heat production upregulates
Term
Normal peak of diurnal temperature
Definition
between 5 and 7pm
Term
Normal low of diurnal temperature
Definition
Between 2 and 6 am
Term
Two benefits of a fever
Definition
correlates with WBC and T and B cell activity and interferon activity and is also implies that bacterial reporduction is being slowed down
Term
Negative aspects of a fever
Definition
Brain damage, fluid loss, increased heart rate, inreased metabolic rate, spetic shock, and discomfort
Term
Occurence of febrile seizures
Definition
Bwetween 2 and 5 % of children 6months to 5 yoa
Term
Characterisitics of a simple febrile seizure
Definition
non focal, less than 15 minutes, do not recur in 24 hours
Term
Risk of occurence or rather reoccurence of a febrile seizure
Definition
<1 yo it is 50% but if >1yo it is 30%, FH of febrile seizures 40%
Term
Non pharmacological treatment of fevers
Definition
clothing and blankets, sponging, works best in fevers over 104 F and with 2 inches of tepid water
Term
Acetaminophen 10 - 15 mg/kg/dose q 4 to 8 hours, NTE 5 doses/24hours
Definition
Normal child dosing of APAP
Term
IBU 5 to 10 mg / kg/dose q 6 to 8 hours
Definition
Normal child dose of IBU
Term
How you should dose all antipyretics for kids
Definition
Weight based
Term
Infant drops of APAP
Definition
80mg/0.8ml
Term
APAP Children's Suspension
Definition
160mg/5ml
Term
APAP Children's Tabs
Definition
80mg per tab
Term
APAP Junior Tablet
Definition
160mg per tab
Term
Adult Tab of APAP
Definition
325mg
Term
Adult ES Tab APAP
Definition
500mg
Term
Infant IBU drops
Definition
50mg/1.25ml
Term
Children's IBU suspension 
Definition
100mg/5ml
Term
Child IBu tab
Definition
50mg
Term
Junior IBU Tab
Definition
100mg
Term
Adult IBU tab
Definition
200mg
Term
54%
Definition
Percentage of 3year olds that have been given OTCs in the past 30 days
Term
22%
Definition
percentage of children in New York survey who had been given OTCs in 2 days prior to survey
Term
Age restriction for OTC products
Definition
No OTC cough/cold meds for children under age 4 and caution if under 12
Term
Avoid multiple ingredient products, recommend APA or IBU alone when indicated, always suggest nonpharmacological mesures first line
Definition
Additional 3 key things you should do as a pharmacist when recommending OTC cough cold meds (besides age restrictions)
Term

An additional non pharmacological measure that can be taken

Definition
Nasal Saline Drops
Term

Non honey cough drops in kids over 1 yoa

and Humidifier do not exceed 50% relative humidity to avoid mold and dust mite gorwth . Use evaporative humidfiier or steam humidier or steam vaorizer

Definition
Humidifier and Cough Drops
Term
DISTILLED WATER
Definition
What should you do if you use a ultasonic water aersolizer?
Term
H202
Definition
What can you use to clean a humidifier?
Term
Painful inflammtn, pharynx tonsils, surrounding areas, 5% of all pediatric visitcs, viral in etiology usually and treatment is symptomatic
Definition
Define Acute Pharyngitis
Term

Inflammation of pharynx and tonsill, patchy discreet exudate, cervial lympadenopahty, NVAbD fever HA Scarltinform rash

 

Definition
Characterize strep throat
Term
Winter and Early Spring
Definition
Seasons when Strep throat commonly occurs
Term
Group A beta hemolytic stretopoccus occurs with 15 go 30 % of acute pharyngitis and 5 to 10% of acute pahrayngitis in adults.  Risk of acute rheumatic fever in children is low and there is a 3% incidence if untreated strep inflammatory disease affecting heart and joints and skin and brain.  Treatment involves: amoxicillin, PCn, cephs, ery
Definition
Bacterial Etology of Strep Throat
Term

Rapid antigen test conducted, if it is neg asume viral in adult if peds, do cultures and treat based on results. 

 

If postive treat with ABX regardless of age

Definition
RADT
Term
3500g
Definition
Average birth weight
Term
6 to 10 % of BW
Definition
Weight lost in first days of life
Term
20 to 25 g per day
Definition
Goal weight gain for children in first four months of life
Term
15g per day
Definition
Goal weight gain past 4months of age thru next 8 months
Term
up to 130 kcal/kg/day
Definition
Nutritional needs of preterm infants
Term
100 to 120 kcal per kg per day
Definition
Nutritional needs of infants 0 to 6 months of age
Term
80 to 100 kcal per kg per day
Definition
Nutritional needs of infant 6 to 12 months of age
Term
1.5g per kg per day
Definition
Protein needs of infants generally
Term
2.2 g per kg per day
Definition
Protein in 0 to 6 months needs
Term
1.6 g per kg per day
Definition
Protein needs in children 6 to 12 months
Term
60 to 80% whey and 20 to 40% casein
Definition
Composition of Human Breast Milk
Term
Whey 90% and Casein 10%, High in proteins  and immunoglobulins and vitamins and minerals
Definition
Human Milk Protein Composition of Colostrum
Term
Whey 60 to 80 % Casein 20 to 40% and produced at 15 days to weaning with approximately 20 to 22 kcal per oz
Definition
Mature Human Milk Composition
Term
Colostrum has more fat and lactose in it and traditional milke is lower in protein and minerals than colostrum
Definition
Comparing Traditional milk (days 6 to 15) to colostrum
Term
lactase.....true lactase deficiency is rare
Definition
What does lactose need to be metabolized?
Term
Contain immuglobulins, dcreased gastroenteritis, decresed diarrhea, less severe respiratory tract infections, less frequent ottits media infections, fewer hospitalizations
Definition
Advantages of breast milk feeding include (immunological benefits)
Term
Better tolerated, convenient, allergies, reduced incdience of over feeding, bonding of mother and child, and cost
Definition
Advantages of Breast Milk Feeding otherwise (besides immunological)
Term
decreased need for vitamin supplements and easier for working mothers, possibly less physical stress on mom, increased bonding of dad and other caregivers
Definition
Advantages of Bottle Feeding
Term
TB, typhoid, herpes, mumps, rubella, HIV, or CMV
Definition
Concerns with Breast Feeding: Contraindications
Term
Illegal substances and nicotine pass into breast milk
Definition
If a mom takes these she should not breast feed
Term
Base formulas, special formulations, preparations
Definition
Types of Formulas available for breast feeding (3)
Term
Milk and Soy
Definition
Two different types of bases:
Term
for term infants, iron fortified, 20 kcal per oz prepared, multiple preparations, consists of non fat cow's milk, vegetable oils, and added carbohydrates
Definition
Milk Based formulas
Term
Enfamil Similac Good Start, Lactose free: Enfamil Lactose free LIPIL and Similac 
Definition
Examples of Milk based Formulas
Term
for infants with lactose or milk preotin intolerance may contain fiber and are genreally soy based, PROSOBEE and ISOMIL
Definition
Soy Based formulas
Term

Low Birth weight and premature < 2kg, whey to casein ratio is 60 to 40, examples

SIMILAC and ENFAMIL PREMATURE LIPIL

Definition
Characterize Special Formulations
Term
For infants with specific illnesses that need modified amounts or types of carbohydrates, fats and lytes
Definition
Therapeutic Formulations
Term
Ready to Use formulation, discard unused portion after *48 hours and refigerate once opened, warm before feeding
Definition
RTU
Term
starts at 40 kcal per oz must be diluted with bottled water or boiled water stable for 28 hours if refrigerated and feed at room temperature (not warm)
Definition
Concentrated Liquid
Term
Must be diluted or mixed to proper strength with either bottled or boiled water and are stable for 48 hours if refrigerated. SERVE warm
Definition
Concentrated Powders
Term
Not recommended, heat only refrigerated formula 4oz or more at a time bottle is uncovered and standing upright heat on full power for not more than 30 miunutes for 4 oz of 45 seconds for 8 oz
Definition
Heating Formulas in the Microwave
Term
replace nipple assemply and invert the bottle 10 times test the formula and watch out for leaching PHYTALATE into milk
Definition
ONce heating is complete of formula:
Term
Infants should not be fed whole milk until 1 year of age 
Definition
Whole milk age restrictions
Term
4 to6 months, one at a time to figure out allergies
Definition
Start solid foods
Term
inflammatory ndtn in the rgn of the perinuem, buttocks, lower ab and inner tighs, aka DIAPER DERMATITIS
Definition
Diaper rash def
Term
eryhtema, skin folds appear normal, mild cases are shiny and red and severe cases involve entire diaper area and macerated, possible signs of secondary infections
Definition
Typical diaper rash presentation
Term
longer than 3 days, inguinal folds, beefy red, satelite legions
Definition
Fungal appearance of diaper rash
Term
topical miconazole or nystatin, +/- topical CCS
Definition
Fungal treatment
Term
staph aureus, micropustules, referral to MD
Definition
Bacterial organisms involved in diaper rash
Term
Secondary herpes or CMV in children that are HIV + , refer to MD
Definition
Types of Viral infections and general info
Term
Plastic pants or double diapers, poor rinsing of deteregents, and failure to change diapers problmpty
Definition
Odd risk factor for viral diaper rash or other risk factors
Term
longer than 7 days, possible secondary infection, persistaent diarrahea or irritability
Definition
When to call MD on diaper rash
Term
polysporin, miconazole, hydrocortef
Definition
Topical treatments of diaper rash
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