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Pediatric Board Review
General pediatrics: Immunizations
15
Biology
Professional
08/06/2013

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Term
Hepatitis B vaccine
Definition
All infants over 2000 g: At birth, 3 doses total, last not before 6 months
Less than 2000 g with Hep B neg mother: Defer until 1 month or hospital discharge, 2 additional doses
Hep B positive mother: Hep B and HBIG regardless of age or size
Less than 2000 g and mother unknown: Vaccine and HBIG, 3 additional doses
Greater than 2000 g and mother unknown: Hep B; HBIG can be delayed up to 7 days
Term
Diptheria vaccine
Definition
DTaP or DT ages under 7
TD or Tdap 7-10 years
Tdap 11 and older
Catch up: 4 doses only if 4th dose given after 4th birthday
Term
Pertussis vaccine
Definition
Tdap for 11-18 years
Can be used in 7-10 years if un or underimmunized for pertussis
Local swelling, fever, anaphylaxis, seizure, crying, swelling, GBS
Less with acellular vaccine
Contra: severe anaphylaxis, severe encephalopathy within 7 days, progressive neuro disorder
Term
Measles vaccine
Definition
Live attenuated
Can be given as young as 6 mos with outbreak, but will require 3rd dose
Fever, febrile seizure, rash, thrombocytopenia, encephalitis
Contra: pregnancy, anaphylaxis, immunosuppressed (not including HIV)
Delayed dose following IG
Vaccines must be 4 weeks apart
Term
Rubella vaccine
Definition
Live attenuated
Lymphadenopathy, fever, rash, arthralgias, arthritis
Contra: Pregnancy, immunocompromised (not including HIV)
Term
Polio vaccine
Definition
Only IPV available in US
Catch up: 3 doses only if 3rd dose administered after 4th birthday
Contra: Severe streptomycin allergy
Term
Varicella vaccine
Definition
70-85% against even mild varicella
12 mos and 4 yrs but can be 4 wks apart
Anyone over age 12 can receive it
Rash
Contra: Pregnancy, T-cell immunocompromised pt (HIV OK if not severe), anaphylaxis to neomycin, concurrent illness
Delay following IG
Term
PCV 13
Definition
Conjugated
Now recommended 4 doses by 15 mos
Healthy children 2-5 years who are not fully vaccinated should receive 1 dose
Single dose should be given age 6-18 years with chronic medical conditions such as cochlear implant, HIV, SSC, congenital heart disease, or 2 doses if underimmunized
Term
PS 23
Definition
Unconjugated
Not to be given under age 2 yrs
Given to children at risk
Give additional dose after 5 years to immunocompromise, sickle cell, asplenia
Adults over 65 years of age with chronic medical conditions
Term
Risk factors for invasive pneumococcal disease
Definition
Sickle cell, asplenia, alaskan natives, HIV, congenital immunodeficiency, cochelar implants, CSF leaks, chronic cardiac disease, renal failure, chronic pulmonar disease, DM, immunosuppresives
Term
FluMist contraindications
Definition
Salicylates, GBS, chronic medical conditions, egg hypersensitivity, age less than 2 years
Term
MCV vaccine
Definition
Not under 2 years of age
Recommended beginning age 11 for all
Booster at age 16 years
Conjugate vaccine always preferred over polysaccharide
Contains strains A, C, W, Y
Recommended in asplenia, complement deficiency, endemic area, HIV
Term
Rotavirus
Definition
Live attenuated
Should be started by 15 weeks, at least 4 weeks apart and completed by 8 months
Contra: altered immunity, moderate to severe illness, GI disease, intussusception, spina bifida, severe latex allergy
Term
Rabies
Definition
Bats, racoons, foxes, skunks: treat unless proven otherwise
Dogs, cats, ferrets: Observe for 10 days and treat with any suspicion
Rodents, rabbits, livestock: No tx
Local wound care, rabies Ig, rabies vaccine (3 additional repeat doses)
Term
Hib
Definition
Primary series starting at 2 months
Booster dose at 12-15 months
Upper age of 59 mos unless immunocompromised
Catch-up: 2 doses if 12-14 months, one dose if 15-59 mos
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