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peads respiratory
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14
Medical
Undergraduate 4
04/15/2017

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Cards

Term
what causes croup
what is the mx?
Definition
parainfluenza virus
mx: oral dexamethasone
oral prednisolone
nebulised steroids
Term
features of whooping cough
Definition
caused by Bordetella pertussis
paroxysmal cough followed by inspiratory whoop and vomiting
in infants: apnoea rather than whoop which is potentially dangerous
diagnosis: culture of organism on per nasal swab, marked lymphocytosis on blood film.
Term
dual infection with which 2 viruses results in severe bronchiolitis
Definition
RSV and human metapneumovirus

infants born prematurely who developbronchopulmonary dysplasia or other underlying lung disease such as CF or congenital heart disease are at risk from severe bronchiolitis
Term
palivizumab
what is it?
what condition is it used in?
how is it administered
whats its benefit
Definition
monoclonal antibody against RSV
used in preterm high risk infants to reduce number of hospital admissions due to bronchiolitis
given IM monthly injections
benefit: reduces hospital admissions but is costly and needs monthly injections
Term
the majority of asthma exacerbations are triggered by which virus?
Definition
infection with rhinovirus
Term
briefly describe pathophysiology of asthma
Definition
genetic predisposition, atopy or environmental triggers cause bronchial inflammation followed by bronchial hyper responsiveness and airway narrowing which cause symptoms such as wheeze, cough, breathlessness and chest tightness
Term
in asthma management when would you add ipratropium bromide in addition to saba?
Definition
in life threatening asthma
Term
what peak flow readings correlate with different severity of asthma?
Definition
>50% perf is moderate
<50% is severe
<33% life threatening
Term
what are the causes of recurrent cough? LEARN off by heart!
Definition
recurrent resp infections
asthma
recuurent aspiration +/- GORD
cigarette smoking: active/passive
habit cough
TB
post specific reap infections e.g. pertussis, RSV, mycoplasma
suppurative lung disease e.g CF, ciliary dyskinesia or immune deficiciency
persistant endobronchial infection
inhale foreign body
airway anomalie: tracheo bronchomalacia or tracheo-oesophgeal fistula
Term
what is Kartegner syndrome characterised by?
Definition
primary ciliary dyskinesia affecting respiratory tract, eustachian tube, fallopian tube and flagella of sperm. PLUS
situs invertus
PLUS
bronchiectasis
Term
which imaging modality is best used to ID bronchiectasis?
Definition
CT
Term
how is CF diagnosed?
Definition
heel prick looks for raised immunoreactive tripsinogen (IRT)
those with raised IRT are screen for common CF gene mutations
infants with 2 mutations have a sweat test to confirm the diagnosis
Term
complications of CF
Definition
nasal polyps, sinusitis, rectal prolaspse
male infertility due to absence of vas deferens
allergic bronchopulmonary asperigillosis (ABPA)
DM often insulin dependent
cirrhosis and portal HTN
distal intestinal obstruction syndrome
pneumothorax or recurrent heamoptysis
Term
what is a pier robin sequence?
Definition
small jaw and cleft palate,

it is an indication for tracheostomy
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