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mean corpuscular Hgb def.
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rbc distribution width def. |
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indication of variation of rbc size |
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vit b12 def, folic acid def. |
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acute blood loss, hemolysis |
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indicates fluid status; if >20 = dehydration |
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if FENa< 1% = dehydration |
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nausea
malaise
headache
altered mental status
depressed deep tendon reflexes
lethargy
seizures
( HANDS LM) |
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isovolemic hyponatremia common cause |
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syndrome of inappropriate ADH hormone SIADH |
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drugs that increase SIADH risk |
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chlorapromide
oxyabazeine
carbamazepine
( all increase ADH release and increase response to ADH) |
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diabetes insipidus which can be of 2 classifications:
central - sudden onset polyuria
nephrogenic - lithmus onset polyuria |
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hypokalemia (apparent cause) |
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beta agonists
insulin
metabolic alkalosis
(BIM) |
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hypokalemia (true) causes |
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Gi loss
renal loss
decreased intake
renal loss includes: diuretics
hyperaldosteronism
amphotericin B
corticosteroids |
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hyperkalemia (apparent) cause |
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hyperkalemia ( true) cause |
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increased intake : cellular/muscle breakdown
salt substitutes
decreased output : renal failure,
ACE-I
ARB ( angiotensin receptor blocker)
beta blockers
trimetoprim |
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Calcium Phosphate Product |
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if > 55 = increased risk for soft tissue calcification |
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alcoholism - poor nutrient intake
diuretics
amphotericin B
vomiting
diarrhea
hypoparathyroidism
hyperaldosteronism
hyperthyroididsm |
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hypomagnesium signs /symptoms |
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muscle twitch
tetany
personality changes
convulsions
stupor
coma
torsades de pointes |
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antacid
laxative
iv fluids/ parenteral nutrition |
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muscle weakness
fatigue
lethargy
hypotension
coma
paralysis
cardiac arrest |
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long term TPN
hypoparathyroidism ( thyroidectomy)
renal failure
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meds that can cause hypocalcemia |
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meds: steroids
bisphosphonates
diuretics |
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hypocalcemia signs/ symptoms |
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finger numbness
tingling in extremities
paresthesia
tetany
chvostek's sign
trousseau's
hypotension
cardiac arrhythmias |
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malignancy
primary hyperparathyroidism
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meds that can cause hypocalcemia |
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calcium supplementation
vit D analogue
estrogen
thiazide diuretics |
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signs / symptoms of hypercalcemia |
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nause
vomiting
abdominal pain
polyuria
polydipsia
ekg changes
ventricular arrhythmias
lethargy
obtundation
pscyhosis
coma
death |
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alcoholism
thiazide/ loop diuretics
intracellular shifiting - refeeding syndrome
excessive use of phosphate binders: calcium containing antacids, sevelamer , lanthanum |
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signs/symptoms of hypophosphatemia |
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muscle wekaness
paresthesia
confusion
obtundation
seizure
coma |
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chronic kidney disease
excessive intake
hyperparathyroidism
treatment of malignancy |
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sings/symptoms of hyperphosphatemia |
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soft tissue calcification |
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used to diagnose AMI
can use by itsel (serial) |
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meds that can increase CK |
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amphotericin B
Clofibrate
ethanol
lithium
halothane
succinylocholine
barbituate poising
im injections
aminocapronic acid
3 hydroxy 3 methylglutaryl coenzyme A reductase inhibitors
Statins
working out |
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< 200 mg/dL
borderline high 200-239
high >240 |
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% of vol that are erythrocytes |
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amount of hemoglobin PER RBC ( HgB/RBC) |
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low MCH (mean corpuscular HgB) - pale RBC- iron deficiency anemia |
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mean corpuscular hemoglobin conc. |
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high rbc's / HgB
disease state in which the proportion of blood volume that is occupied by red blood cells increases. Blood volume proportions can be measured as hematocrit level.
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rbc volume - MCV - mean cell volume ( average number of rbc's) |
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what is normocytic anemia |
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occurs when the overall hemoglobin levels are decreased, but the red blood cell size (mean corpuscular volume) remains normal
MCV 81-99 fL. |
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what is macrocytic anemia |
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In a macrocytic anemia the larger red cells are always associated with insufficient numbers of cells and often also insufficient hemoglobin content per cell |
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thrombocytosis /thrombocythemia |
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measurement of avg. size of platelets |
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amount of time it takes 4 blood to clot |
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D-dimer is a fibrin degradation product a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrinogen protein.[1]
D-dimer concentration may be determined by a blood test to help diagnose thrombosis. |
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incrased fibrinogen and increased fibrin degredation indicate |
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disseminated intravascular coagulation- In DIC, the processes of coagulation and fibrinolysis are dysregulated, and the result is widespread clotting with resultant bleeding. |
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neutrophils are the ___ response to infection
less mature neutrophils are called ___and are ___ in infections
bands are ___ neutrophils
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first
bands / stab; elevated
immature |
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leukocytes tat engulf/digest other cells |
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recognize non self cells that alert NK, T, B, cells (lymph NKTB < like new kids on the block) |
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HIV type 1
radiation exposure
glucocorticosteroids
lymphoma (hodgkin's disease)- a cancer of lymph tissue found in the lymph nodes, spleen, liver, bone marrow, and other sites.
aplastic anemia - condition where bone marrow dosn't make sufficient new cells to replace old ones |
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viral infection
lymphomas |
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increase in number of neutrophil cells ( due to infection usually and if u have left shift then your bands increase and all your other cells will decrease) |
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high band cell count; usually due to infection >5% |
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normal reporting order of differential |
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segs/ bands/ lymph/mono/ eosino/ baso
"some bands like mooning every babe" |
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bloodstream
cerebrospinal fluid
pericardinal fluid
pleural fluid
peritoneal fluid- lubricates abdominal cavity
synovial fluid - in synovial joints
bone
urine (directly from kidney/bladder) |
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staphlococcus
streptococcus
corynebactrum |
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streptococcus
haemophilus |
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bacteroide
escherichia
klebsiella pneumonia
enterococcus
streptococci |
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streptococcus
staphlococcus
lactobacillus
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common stains to ID fungi |
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KOH
India ink
periodic acid schiff
gomori methenamine silver stain
acid fast
gram stain
wright or giemsa stain |
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purifeid protein derivative - inect into skin and ppl that have been exposed to hiv will have a hypersenstitivity rxn to it |
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tests done to diagnose hiv |
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elisa (EIA) and western blot to confirm |
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((140-age)x weight)/ 72x Scr
and x .85 if female |
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male is 50+2.3(in over 5 ft.)
female is 45.5 +2.3(in over 5 ft) |
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IBW+.4(actual - IBW)
use adjusted body weight when actual is >120 % of IBW
actual/ibw x100 |
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BUN:Scr ratio of > 20:1 means...
if between 10 - 20 means... |
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dehydration; volume depletion- pre renal
intrinsic kidney damage |
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what do you use to estimate GFR? |
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MDRD- modification of diet in renal disease |
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rbc's in urince could mean... |
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glomerulonephritis (kidney filter function is damaged)
infection
renal infarction
papillary necrosis
tumors
stones
coagulopathies |
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wbc's in urine could mean |
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uti
glomerulonephritis
intersitial nephritis ( inflammatory conditions) |
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protein in urine could mean...
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