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PBD II
Keller Wood
39
Physiology
Graduate
02/01/2011

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Term
The ________ ducts are stimulated by ______ and produce the male internal genitalia.
Definition
Wolffian, testosterone
Term
These two hormones are released by the fetal testes for male sex differentiation.
Definition
Testosterone, MIF
Term
The ______ducts become the female internal genitalia.
Definition
Mullerian
Term
In males, LH and FSH stimulate the _______ to produce ______, which has a +/- feedback effect?
Definition
testes, testosterone, -
Term
In females, LH and FSH stimulate the ovaries to produce ______ and ______.
Definition
estradiol, progesterone
Term
In males, these cells produce testosterone and are stimulated by ___.
Definition
Leydig, LH
Term
In males, the cells are most important for sperm production. They are stimulated by ____.
Definition
Sertoli, FSH
Term
In males, these cells produce inhibin.
Definition
Sertoli
Term
The RLS in steroid hormone production in the conversion of _____ to _____ by P450scc.
Definition
cholesterol, pregnenolone
Term
During steroid hormone synthesis, Pregnenolone is hydroxylated to _____
Definition
DHEA
Term
This enzyme converts Testosterone to DHT
Definition
5 alpha reductase
Term
This enzyme converts testosterone to estrogens
Definition
aromatase
Term
T/F GnRH is released from the hypothalamus in pulses in both males and females
Definition
T
Term
_____ is responsible for the development of the epididymis, vas deferens, and seminal vesicles in the fetus
Definition
Testosterone
Term
___ is responsible for the development of the penis, scrotum, and urethra
Definition
DHT
Term
____ has the greatest effect of the development of the prostate and the descent of the testes
Definition
DHT
Term
T/F Estrogen is responsible for the epiphyseal closure at puberty in both males and females
Definition
T
Term
Low levels of this enzyme would result if the male external genitalia being underdeveloped until puberty
Definition
5a reductase
Term
T/F Estradiol can have both a positive or negative feedback on pituitary.
Definition
T
Term
This cell type is responsible for producing androgens in women
Definition
thecal
Term
This cell type converts androgens to estrogens and the enzyme is _____
Definition
Granulosa, aromatase
Term
During the follicular phase, ____ cells respond to LH and ____ cells respond to FSH
Definition
thecal, granulosa
Term
During the follicular phase of the ovarian cycle, the release of estradiol results in a +/- feedback at midcycle?
Definition
+
Term
Stimulation from this hormone causes the formation of the corpus luteum
Definition
LH
Term
LH stimulates secretion of _____ and _____ from corpus luteum
Definition
E and P
Term
During the luteal phase, E and P produce +/- feedback, which results in an increase/decrease in LH and FSH secretion
Definition
-, decrease
Term
What causes menses?
Definition
decrease in FSH and LH --> decrease in E and P
Term
In females, this hormone reduces plasma FSH and is secreted by these cells
Definition
inhibin, granulosa
Term
What causes the low amplitude, pulses during the follicular phase?
Definition
E - feedback
Term
During midcycle, amplitude and frequency are highest due to ?
Definition
E + feedback
Term
The luteal phase has the lowest frequency pulses due to ?
Definition
P - feedback
Term
This hormone is reponsible for the growth of endometrium, vasculature, and endometrial glands (proliferative phase)
Definition
E
Term
This hormone is responsible for the secretion from endometrial glands (secretory phase)
Definition
P
Term
During menopause, LH and FSH increase/decrease?
Definition
increase (reduced - feedback)
Term
This hormone is responsible for decreased myometrial E receptors and thick cervical mucous
Definition
P (during luteal phase)
Term
T/F Women tend to have a better lipid profile than men b/c E decreases total cholesterol and LDL production and increases HDL production
Definition
T
Term
Increased levels of LH stimulate ____ production by the thecal cells
Definition
androgen
Term
Increased levels of ____ leads to follicular growth and increased conversion of adrogens to estrogens by ______(enzyme) in the ____ cells
Definition
FSH, aromatase, granulosa
Term
Very high levels of E results in +/- feedback which causes a surge of ____
Definition
+, LH
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