Term
| Where in the hypothalamus are the cell bodies that release GHRH? |
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Definition
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Term
| How many forms of GHRH are there and how many amino acids are each? |
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Definition
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Term
| How many forms of Somatostatin are there and what is the chain length of each? |
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Definition
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Term
| T/F Plasma levels of GH are very episodic. |
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Definition
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Term
| ____ leads to surges of GH, whereas ____ inhibits secretion of GH |
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Definition
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Term
| Besides GHRH, what is the other potent stimulator of GH secretion? Does it act on the same receptor as GHRH? |
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Definition
| ghrelin, no (GH secretagogue receptor) |
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Term
| Which amino acid is known to stimulate the hypothalamus to produce GHRH? |
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Definition
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Term
| Amino acids, niacin, serotonin, dopamine, stress, and sleep stimulate/inhibit the release of GHRH? |
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Definition
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Term
| Where are the cell bodies that release SRIF located? |
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Definition
| periventricular area of hypothalamus |
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Term
| What hormone is responsible for the long-loop feedback control of GH? Increase in this hormone leads to an increase/decrease in GHRH and an increase/decrease in SRIF. |
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Definition
| IGF-1, dec GHRH, inc SRIF |
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Term
| What effect does IGF-1 have on the pituitary? |
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Definition
| interferes with GHRH binding |
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Term
| What hormone is responsible for the short-loop feedback control of GH? |
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Definition
| GH. Negative feedback on the brain to dec GHRH and inc SRIF |
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Term
| What hormones regulate the ultra-short-loop feedback control of GH |
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Definition
| GHRH and SRIF. Involved in moment to moment GH secretion |
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Term
| The actions of GH are mediated via a class of proteins called _____? |
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Definition
Insulin-like growth factors (IGFs)
The synthesis of IGF-1 is induced by GH. |
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