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Pathophysiology
Exam 2 flash cards
46
Physiology
Not Applicable
02/22/2011

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Term
Arteries
Definition
thick walled, large amount of elastic fibers, high pressure but low volume;
Mean arterial pressure (MAP) 90-100 mm/Hg, small arteries 60-90, arterioles 40-60.
Term
Capillaries
Definition
microscopic, single-thickness vessels connect arterial and venous segments of
circulatory system, approximately 10 billion capillaries @ 26-32 mm/Hg.
Term
Veins
Definition
and venules; thin-walled, distensible but collapsible vessels, high volume but low pressure; Pressures at 0-10 mm/Hg even in the vena cava (64% of circulating volume).
Term
Hemodynamics
Definition
oxygen in blood stream
Term
cardiac output
Definition
volume of blood out per min
Term
Stroke volume
Definition
volume of blood out per beat
Term
cardiac preload
Definition
EDV determined, amount of blood that fills ventricle at rest
Term
Cardiac afterload
Definition
determines ESV, resistance of rejection from left ventricle
Term
Myocardial contractility
Definition
Determines ESV, speed of myocardium shortening fibers
Term
Myocardial distensibility
Definition
EDV determined, willingness of myocardium to stretch
Term
preload
Definition
work imposed on heart(a measure)
Term
afterload
Definition
resistance to ejection
Term
leading us cause of death
Definition
atherosclerosis
Term
atherosclerosis
Definition
fatty streak layer, fibrous plaque..developes by vessel injury and normal mechanisms of repair. vascular cells multiply.
Term
atherosclerosis
Definition
risk factors: high blood cholesterol and/ or dislipidemia
Term
chronic aterial insufficiency
Definition
intermittent claudication
Term
chronic arterial insufficientcy
Definition
PAOD, atherosclerosis in popliteal, femoral
Term
Buerger's disease
Definition
thromboangiitis obliterans, thrombus formation...occurs in lower leg and foot. sensitive to cold and shinny thin skin
Term
Raynauds syndrome
Definition
vasospasms of arteries in fingers and toes. ischemic episode- pallor(cold, numbness), cyanosis(swelling). hyperemia
Term
hyperemia
Definition
triphasic color, progression...will return to normal color
Term
Aneurysms
Definition
abnormal localized arterial wall dilatation
Term
berry or sacular aneurysms
Definition
circle of willis, small, spherical 1.5 diameter
Term
fusiform anyeurysms
Definition
ascending aorta------abdominal aorta
Term
chronic venous insufficiency
Definition
varicose veins- dilated or torturous veins of lower extremities.
cause: prolonged dilatation and stretching of vascular walls.
Term
chronic venous insufficiency
Definition
can lead to edema and stasis ulcers
Term
acute venous thrombosis
Definition
clot vs inflammation, risk factors: immobilization, trauma, heart failure, shock, hypercoagulability. symptoms: unilateral pain, swelling, deep muscle tenderness, positive Homan's sign; fever. *clot breaks off and clogs a vein, cuts off blood flow causing ulmonary embolism. right ventricular failure
Term
compartment syndrome
Definition
increased pressure in limited space; impairing circulation and producing ischemic tissure injury......caused from decreased in compartment size or increase in volume of contents.
Term
pulse pressure
Definition
different between systolic and distolic pressure
Term
mean aterial pressure
Definition
average pressuree in arterial system during both ventricular contraction and relaxation... 1/3 of pulse pressure added to diastolic pressure
Term
most common cardiovascular problem
Definition
hypertension
Term
#2 for kidney failure and blindness
Definition
uncontrolled hypertension
Term
90-95% of all cases of chronic HBP
Definition
primary hypertension
Term
primary hypertension
Definition
symptoms: headache on back of head or neck. typically asymptomatic.
environmental factors: alcohol, stress, high salt intake, oral contraceptives, tobacco.
Term
primary hypertension
Definition
loss of elastic fibers, increase atheroma formation, increased collagen and calcium deposits. high blood pressure in children
Term
secondary hypertension
Definition
malignant hypertension
Term
malignant hyertension
Definition
marked elevations of systoic and diastolic. diastolic above 120. symptoms: retinopathy, papilledema, confusion, lead to convulsions. treatment: therapy, IV diazoxide, sodium nitroprusside.
Term
pregnancy induced hypertension
Definition
gestational hyertension...within 120 days
Term
pregnancy induced hypertension
Definition
PIH or GHTN, without proteinuria(blood vessels leak)
Term
before 20 weeks...of pregnancy induced hypertension
Definition
PIH/GHTN, systolic pressure increases 30 mm Hg or greater. diastolic pressure increases 15 mm Hg
Term
after 20 weeks...of pregnancy induced hypertension
Definition
gestation values of 140 systolic or 90 diastolic. proteinuria= preeclampsia
Term
PIH
Definition
occurs in 1st pregnancies, teen pregnancies, above 40 yr. risk factors: obesity, hyperglycemia, kidney disease, autoimmune diseases.
Term
gential warts
Definition
condylomata-greek for.....
HPV....mainly HPV 6 and 11. incubation 6wks to 8 months. enters mucous tears and infects basal cells of epithemlium. non-lytic virus. epithelial cells hypertrophy in virus presence. form soft fleshy tumor...pink
Term
Genital herpes
Definition
HSV-1 oral...HSV-2 genital. HSV are neurotrophic, grow within neurons, latency. transmission through fluids. lytic. point of initail contact and move down nerve to skin. incubation period 2-10 days. primary infection is a smptomatic person but seronegative. virus is shead in month after lesion.
Term
Chlamydia trachomatis
Definition
incubation 2 wks. reiters syndrome. elemental bodies are infective and reticulate are not. elemental bodies infect other cells that shed ruptured tissues and present a local inflammatory response. can lead to scarring of fallopian tubes.
Term
Syphilis
Definition
Treponema pallidum, sensitive to drying, heat, disinfectants. mucous membrane or skin lesions contact. also transplacentally to fetus. replicate extracellularly. local symptoms on site, but with systemic course if untreated. primary(6months ulcer), secondary(3-6wks treponemes), tertiary syphilis(gummas, neurosyphilis, paresis).
Term
Gonorrhea
Definition
Neisseria gonorrohoeae, incubation 2-5 days to 3 weeks. PID pelvis inflammatory disease. signs: urethritis, cervicitis, proctitis, pharyngitis, conjunctivitis. shedding of fluids, mucosa, pathogen. direct contact with epithelial surfaces.
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