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Pathophysiology
Focus 1 & 2 First Exam
50
Pathology
Undergraduate 3
09/13/2010

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Cards

Term
Pathology
Definition
Study of disease
Term
Physiology
Definition
Study of the function of the body
Term
Pathophysiology
Definition
Study of how disease alters the function of the body
Term
Cell differentiation
Definition
- A normal process in development in which cells become structurally and functionally different from one another and develop a mature phenotype
-Common to all cells.
Term
Cell differentiation
Definition
- A normal process in development in which cells become structurally and functionally different from one another and develop a mature phenotype
-Common to all cells.
Term
Functions common to all cells (4)
Definition
Metabolic absorption, Excretion, Respiration, Communication
Term
Functions common to some NOT all cells (4)
Definition
Movement (muscle), Conductivity (nerve), Secretion (mucus glands), Reproduction (nerve cells can NOT reproduce)
Term
Nucleus stores what?
Definition
DNA/RNA, gene info
Term
Functions of nucleus
Definition
Cell division, control of genetic info, replication and repair of DNA, transcription of DNA
Term
Ribosomes
Definition
Sites for cellular protein synthesis
Term
Lysosomes
Definition
Contain enzymes for digestion of protein, fats, and carbohydrates
Term
Mitochondria
Definition
Generate most of cell's ATP
Term
Functions of Plasma Membrane
Definition
Structure, Protection, Activation of cell, Storage/transport, Cell-to-cell interaction (See notes for more detail)
Term
Cellular Metabolism definition
Definition
Energy produced from breakdown of proteins, fats, and carbohydrates is transferred to ATP (energy)
Term
Where does cellular metabolism occur?
Definition
Mitochondria
Term
Diffusion
Definition
Solute moves from high concentration to low concentration
Term
Colloid osmotic pressure
Definition
Due to plasma proteins
Term
Hydrostatic pressure
Definition
Due to pumping of the heart
Term
Osmosis
Definition
Water moves to make concentration even
Term
Passive Mediated Transport (2 parts)
Definition
1. Direction of movement is the same as diffusion (high-low) 2. No energy required.
Term
Active Mediated Transport (2 parts)
Definition
1. Molecules move against concentration gradient 2. Requires energy
Term
Three varieties of Membrane Transport
Definition
1. Uniport 2. Symport 3. Antiport
Term
Exocytosis
Definition
In --> Out (solute)
Term
Endocytosis
Definition
Out --> In (solute)
Term
Muscle tissue
Definition
Voluntary/Involuntary movement, Voluntary/Involuntary contractions
Term
Connective tissue
Definition
Binds tissues and organs, storage sites for excess nutrients.
Term
Epithelial tissue
Definition
Covers most internal/external surfaces. Functions - protection, absorption, secretion, excretion
Term
Neural tissue
Definition
Receives and transmits electrical impulses
Term
Mitosis
Definition
Cell division, daughter cells are identical to parent cells
Term
Meiosis
Definition
daughter cells have 1/2 genetic material of parent cells
Term
Atrophy
Definition
Same number of cells but cells have shrunk
Term
Hypertrophy
Definition
Same number of cells but cells are bigger
Term
Hyperplasio
Definition
Normal size but more cells
Term
Metaplasia
Definition
Normal size but look different, bigger in number
Term
Hypertriphy and hyperplasia
Definition
Cells divide and get bigger
Term
Dysplasia
Definition
Hyperplasia + Metaplasia = precancerous, cells are abnormal
Term
Hyperplasia occurs in what type of cells
Definition
Dividing cells
Term
A reversible replacement of one mature cell type with another less differentiated cell type
Definition
Metaplasia
Term
Dysplasia
Definition
Abnormal changes in size, shape, and organization of mature cells
Term
Infectious agents examples
Definition
bacteria, viruses, etc.
Term
Physical and mechanical factors example
Definition
stab wound
Term
Genetic factors example (cellular injury)
Definition
Sickle cell
Term
Nutritional imbalances (cellular injury)
Definition
protein deficiency
Term
Hypoxia
Definition
Lack of oxygen
Term
Free radicals
Definition
unstable molecules - unpaired electrons
Term
Chemical Agents
Definition
Damage to cell's plasma membrane leading to increased permeability (leaky cell)
Term
Common cellular injuries (3)
Definition
Lead, Carbon monoxide, Ethyl alcohol
Term
Coagulative necrosis (4 total - 2 parts)
Definition
1. Kidneys, heart, adrenal glands 2. Hypoxic injury
Term
Liquefactive necrosis (2 parts)
Definition
1. Brain 2. Ischemic injury (lack of blood flow)
Term
Caseous necrosis (2 parts)
Definition
1. Lungs with TB 2. Clumped cheese appearance
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