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Pathophysiology
Defense Systems-innate, inflammation, and acquired
31
Nursing
Graduate
06/14/2011

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Cards

Term
Goals of inflammation
Definition
1. limit control and process
2. prevent and limit infection/further damage
3. Initiate adaptive immune response
4. initiate healing
Term
H1 Receptor
Definition
proinflammatory
Term
H1 Receptor
Definition
proinflammatory
Term
H2 Receptor
Definition
Antiinflammatory
Term
Diapedesis
Definition
Emigration of cells through the endothelial junctions
Term
Margination
Definition
adherence of leukocytes to endothelial cells
Term
fibrinous exudate
Definition
thick
clotted
indicates more advanced inflammation
Term
leukocytosis
Definition
-manifestation of inflammation
-increased numbers of circulating leukocytres
Term
epithelialization
Definition
sealing the wound
Term
contraction
Definition
shrinking the wound
Term
active immunity
Definition
reaction of your own system
WBC
Term
passive immunity
Definition
borrow immune agents form another person
ab
Term
allergy
Definition
deleterious effect of hypersensitivity to environmental Ag
Term
Autoimmunity
Definition
disturbance in the immunologic tolerance of self antigens
Term
Autoimmunity
Definition
disturbance in the immunologic tolerance of self antigens
Term
alloimmunity
Definition
immune reaction to tissues of another individual
Term
Hypersensitivity Type I
Definition
IgE
desensitization
Term
Hypersensitivity Type II
Definition
tissue specific
Term
Hypersensitivity Type III
Definition
immune complex mediated
Term
Hypersensitivity Type IV
Definition
-cell mediated
-no Ab
-Tc, Th1
-graft rejection, Tb skin test, allergic rxns
Term
Neoantigen
Definition
haptens become immunogenic when they ind to host
Term
What are the factors of infection
Definition
1.Mechanism of action
2.Infectivity
3. Pathogenicity
4. Virulence
5.Immunogenicity
6.Toxigenicity
Term
Vaccines
Definition
Induction of long-lasting protective immune responses that will not result in disease in a healthy recipient
Term
IgG
Definition
most common
smallest
works with complement to lyse cell
Term
IgM
Definition
-found in blood stream
-1st produced after 1st exposure (like after immunization)
Term
IgD
Definition
-found in tiny amounts
-stimulates B cells to divide and secrete Ab
Term
IgA
Definition
produced by plasma cells under the skin
-spit, tears, mucus, breast milk, saliva
Term
IgE
Definition
-allergic reactions
-found on basophils and mast cells
Term
Function of Ab's
Definition
1.Precipitation
2. Neutralization
3. Opsonization
4. Complement activation
Term
Complement
Definition
blood protein
IgG to lyse cell walls
Term
Kinins
Definition
small polypeptides that cause vasodilatation
causes swelling and produces pain
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