Term
| characteristics of cancer cells |
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Definition
1. lack of contact inhibition
2. inability to differentiate
3. derive from a single cell
4. abnormal cell proliferation
5. local tumor formation
6. invasion of surrounding tissue
7. ability to metastasize |
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Term
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Definition
1. carcinogen damages DNA
2. Changes a specific gene in cell
3. Gene undergoes repair
4. Gene mutates or mutate and produces cancer cell line |
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Term
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Definition
| genes that encode proteins to promote cellular proliferation |
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Term
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Definition
| mutations in proto-oncogene yields uncontrolled growth stimulatory proteins |
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Term
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Definition
| uncontrolled growth and replication of cells |
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Term
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Definition
| polypeptides that influence cellular growth, differentiation, and survival |
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Term
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Definition
-energize growth stimulating pathways to stay open
-signal protein receptors in cytoplasm to proliferate
-transmit growth stimulating signals to other growth factor receptor cells in tissue
-Signal transcription factors to induce cell cycle |
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Term
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Definition
| tumors form new blood vessels |
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Term
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Definition
| cancer cells can form new colonies |
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Term
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Definition
| cancer cells can form new colonies |
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