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Pathophysiology Test #1 The Cell
The Cell
32
Nursing
Graduate
06/10/2011

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Cards

Term
Cellular Functions
Definition
1. Movement
2. Conductivity
3. Metabolic Absorption
4.reproduction
5.Secretion
6. Excretion
7. Respiration
8 Communication
Term
Nucleus
Definition
-Control Center
-Contains DNA
-Functions in cell division and control of genetic info
Term
Mitochondria
Definition
devoted to energy production
Term
Ribosome
Definition
site of protein sysnthesis
Term
Lysosome
Definition
digestive activities
Term
Golgi Apparatus
Definition
wraps cell products for secretion or storage within the cell
Term
Endoplasmic reticulum
Definition
synthesis of protein and lipid components of organelles
Term
Plasma Membrane
Definition
-gives the cell shape
-attaches one cell to another
-controls movement from one compartment to another
-cell to cell recognition
Term
Functions of Plasma Membrane
Definition
-Structure
-Protection
-Activation of cell
-Transport
Term
Composition of Membrane
Definition
-outer surface dimpled with cavelike indentions called caveolae
-major chemical components of all membranes are lipids and proteins
Term
Proteins of Plasma Membranes
Definition
-Integral membrane proteins are embedded int he lipid bilayer
-peripheral membrane proteins reside at one surface or the other
-membran functions determined by proteins
Term
Role of proteins in cellular membrane
Definition
-facilitate movement of substances in and out of cell
-transport channels for electrolytes
-Na/K pump
-Cell surface markers
-Cell adhesion
-Catalyst for chemical reactions
Term
Carbohydrates in the Plasma Membrane
Definition
-found in the plasma membranes glycoprotein
-function in intracellular recognition needed for tissue formation
Term
Cellular Receptors
Definition
Protein molecules on the plasma membrane in the cytoplasm or in the nucleus
-can recognize and bind in specific smaller molecules called ligands
Term
Cell to cell adhesion
Definition
-plasma membranes allow groups of cells to be held together to form tissues and organs
Term
extracellular matrix
Definition
intricate framework of fibrous proteins embedded in a watery gel like substance composed of complex CHO
Term
atrophy
Definition
decrease in size but no loss in function
Term
hypertrophy
Definition
increase in size of cell and then organs
adaptive changes to increased stress
Term
hyperplasia
Definition
-increase in # of cells
-response to increase in demand
-not all cells are capable of this
Term
metaplasia
Definition
reversible replacement of one mature cell type by another cell type
Term
dysplasia
Definition
-abnormal changes in size, shape, and organization of mature cells
-Not truly adaptive
Term
Physical injury to cell: toxic
Definition
-lead posioning
-carbon monoxide
-ethanol
-social/street drugs
Term
Manifestations of Cellular Injury
Definition
-injury causes degenerative changes within the cell
-reversible if stimulus is removed, lethal if not
-involved the cytoplasm
Term
Cellular Death
Definition
-noxious stimulus is severe or long lasting
-irreversible b/c cell is no longer able to compensate
Term
effects of necrosis
Definition
-loss of function
-leaking enzymes
-focus of infection
-inflammatory response
Term
coagulated necrosis
Definition
-caused by ischemia
-most common type
-cells maintain outline for a time depending on lytic enzyme activity
Term
liquefactive necrosis
Definition
-common ischemic injury to neurons and glial cells
-cells digested by their own enzymes, become soft, and liquified
Term
Caseous Necrosis
Definition
dead cells disintegrate
debris not completely digested
Term
Fat necrosis
Definition
-occurs in breast, pancreas, and abdominal area
-break down of triglycerides by lipaes relaeasing free fatty acids
-combine with Na, Ca, Mg ions creating soaps
Term
Gangrene
Definition
-results from severe hypoxic injury
-superimposed growth of bacteria
-occurs when necrotic tissue is exposed to bacteria
Term
Apoptosis
Definition
-active process of cellular self destruction
-nuclear and cytoplasmic shrinkage of a cell followed by fragmentation into membrane bound fragments and subsequent phagocytosis
Term
Cellular Aging
Definition
Irreversible and universal processes at the cellular and molecular level
-Cellular changes include atrophy, decreased function, and loss of cells
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