Term
|
Definition
<65 yr
progressive dyspnea
S3(too much filling)
pulmonary congestion
cardiomegaly
<50% ejection fraction |
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Term
|
Definition
>65 years
acute dyspnea
S4 (extra beat at first)
pulmonary congestion
left ventricular hypertrophy
normal or small heart
> 50% ejection fraction |
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Term
|
Definition
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Term
|
Definition
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|
Term
Left Ventricular failure Backward effects |
|
Definition
dec. ejection fraction-->inc. left vent. preload-->inc. left atrial pressure-->inc. pulmonary pressure-->pulmonary congestion. and inc. right vent. afterload which-->right vent. hypertrophy |
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|
Term
Left Ventricular failure forward effects |
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Definition
dec. cardiac output--> dec. tissue perfusion. RAAS activation-->fluid retention which--> inc. left vent. preload (backward effect). |
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|
Term
left sided heart failure leads to? |
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Definition
right sided heart failure. but not opposite. |
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Term
left vent. failure backward S/S |
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Definition
Immediate
Dyspnea on exertion
orthopnea
cough
paroxismal nocturnal dyspnea
cyanosis (late sign)
basilar crackles
acute pulmonary edema |
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|
Term
Left Vent. failure forward S/S |
|
Definition
fatigue
oliguria
inc. Heart rate
faint pulses
Brain: restlessness, confusion, anxiety |
|
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Term
|
Definition
ischemic caridomyopathy
Caused by CAD and HTN |
|
|
Term
Systolic CHF basic pathophys |
|
Definition
impaired contractility
ischemia-->no ATP-->negative inotrope-->
Sympathetic nerv. system stimulates beta receptors-->over stimulation. |
|
|
Term
diastolic CHF basic pathophys |
|
Definition
heart can't fill
common: women, elderly, no prev. MI
impaires calcium removal from muscle |
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|
Term
right vent. failure backward effects |
|
Definition
dec. ejection fraction-->inc. right vent. preload-->inc. right atrial pressure-->systemic congestion |
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|
Term
Right vent. failure forward effects |
|
Definition
dec. output to left vent.-->dec. left vent. cardiac output-->dec. tissue perfusion. RAAS activation-->fluid retention-->inc right vent. preload(backward effect). |
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|
Term
Right vent. failure backward S/S |
|
Definition
hepatomegaly
ascites (portal vein couldn't handle pressure)
splenomegaly
anorexia(pressure on gastric area)
subcutaneous edema
jugular vein distention
kidney congested (dec. GFR kicks in RAAS) |
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|
Term
Right vent. failure forward S/S |
|
Definition
dec. perfusion:
fatigue
oliguria
inc. heart rate
faint pulses
restlessness, confusion, anxiety
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|
|
Term
|
Definition
|
|
Term
Heart Failure nervous sys. pathway for compensation |
|
Definition
Baroreceptor response-->brain-->SNS activation-->inc. heart rate and contractility-->inc. cardiac output.
Heart is poorly Oxygenated so this increases failure |
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|
Term
Heart failure kindney pathway for compensation |
|
Definition
dec. GFR-->RAAS activation-->kidney-->fluid retention-->inc. preload-->inc cardiac output.
heart is poorly oxygenated so this increases failure |
|
|
Term
heart failure Heart pathway for compensation |
|
Definition
inc. vent. wall tension-->heart-->myocyte growth-->hypertrophy-->inc. cardiac output.
increases failure |
|
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Term
|
Definition
diuretics
keep upright
raise legs (not above heart)
low sodium diet |
|
|
Term
|
Definition
|
|
Term
to improve contractility of heart |
|
Definition
O2(positive inotrope)
inotropes(digoxin) |
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|
Term
|
Definition
BB's (difficult to control)
control symptoms
diuretics |
|
|
Term
potential complications of left sided heart failure |
|
Definition
pulmonary edema
pleural effusion
renal insufficiency (forward effect)
dysrhythmia
LV thrombus(static blood)
cardiogenic shock (inc. pre/afterload)
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|
|
Term
potential complications of right sided heart failure |
|
Definition
renal insufficiency
hepatomegaly
splenomegaly
dysrhythmia
cardiogenic shock
LV thrombus? |
|
|
Term
|
Definition
|
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Term
|
Definition
Vent. depolarization and atrial repolarization |
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|
Term
|
Definition
|
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Term
|
Definition
|
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Term
|
Definition
|
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Term
|
Definition
|
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Term
|
Definition
|
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Term
|
Definition
doesn't open completely
inc. cardiac workload |
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Term
|
Definition
doesn't close completely
increases cardiac workload |
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Term
|
Definition
Diastolic murmer
elevated LA pressure |
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Term
|
Definition
hypertrophy of LA and LV
regurgitant flow through mitral valve
systolic murmer |
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|
Term
|
Definition
LV hypertrophy
dec. CO
Slow heartbeat
systolic murmer |
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|
Term
|
Definition
LV hypertrophy
head bobs as heart beats
diastolic murmer
|
|
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Term
|
Definition
pulmonary HTN
right vent. hypertrophy
acyanotic
(RV hypertrophy reverses to become cyanotic) |
|
|
Term
Ventricular septal defect |
|
Definition
acyanotic till RV hypertrophy, then blood reverses into LV to become cyanotic |
|
|
Term
|
Definition
acyanotic
ductus between ascending aorta and pulmonary artery |
|
|
Term
|
Definition
narrowing of the aorta
dec. BP to lower body
prone to intercranial hemorrhage
arm and head BP inc.
can lead to CHF |
|
|
Term
|
Definition
pulmonic valve stenosis
RV hypertrophy
Ventricular septal defect
overriding aorta
Prone to: infective endocarditis. Polycythemia (baby bone marrow making up for lack of O2).
only one that starts cyanotic |
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Term
|
Definition
oxygenated blood spilling into deoxygenated blood |
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Term
|
Definition
deoxygenated blood spilling into oxygenated blood |
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|
Term
|
Definition
|
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Term
|
Definition
undissolved material that occludes pulmonary vasculature |
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|
Term
|
Definition
usually caused by orthopedic surgery(pelvis and femur) or trauma |
|
|
Term
pulmoary embolism etiologies |
|
Definition
thromboses, labor(amniotic fluid and hair), air, tumor, foreign bodies(man made:sutures, needle caps, bullets), infection, parasites, DVT |
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Term
|
Definition
hypercoaguable state
damage to vessel wall
venous stasis |
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|
Term
pulmonary embolism pathogenesis |
|
Definition
thrombus forms-->trauma/excercise/change in blood flow dislodge it-->IVC-->RA-->RV-->lodges in pulmonary vasculature-->SNS response and release of serotonin, histamine, prostaglandins-->vasoconstriction of pulmonary vasculature-->steep pulmonary HTN-->R sided heart failure and dec. CO-->hypotension-->shock(most people die from this)-->SNS response and release of serotonin, histamine, prostaglandins-->pulmonary artery and bronchial artery constriction-->respiratory arrest |
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|
Term
pulmonary embolism clinical manifestations |
|
Definition
may not appear until late.
1st: restlessness, anxiety, apprehension
dyspnea(sudden onset is bad sign)
feelings of impending doom
CP, inspiratory pain, hemoptysis
pleuritic CP (hurts to breath in) |
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|
Term
pulmonary edema diagnostics |
|
Definition
Va/Q (high?)
ABG's: dec. PaO2, dec. PCO2, inc. PH
EKG: ST and T wave changes
CXR: effusions and infiltrates
pulmonary angiogram (conclusive test) |
|
|
Term
|
Definition
prevention of DVT's
O2, anticoagulants, thrombolytics, filter in IVC, embolectomy |
|
|
Term
Acute respiratory distress syndrome |
|
Definition
sudden, progressive respiratory failure with severe dyspnea, refractory (doesn't respond to Tx) hypoxemia, and diffuse bilateral infiltrates |
|
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Term
|
Definition
direct or indirect pulmonary trauma(non cardiogenic)-->massive inflammatory response that increases alveolar cappillary membrane permeablility-->fluid, fibrin, blood, and protiens shift from vasculature into interstitial space-->inc. space between capillary membrane and alveolar membrane--> dec. gas exchange--fluid shifts into alveoli-->pulmonary edema-->dec. gas exchange-->after 7-10 days, dec. surfactant-->atelectasis-->2-3 weeks, irreversible pulmonary fibrosis-->dec. gas exchange and dec. compliance |
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Term
|
Definition
hypoxemia refractory to oxygen leading to:
hypotension
dec. UO
respiratory acidosis
metabolic acidosis
cardiopulmonary arrest |
|
|
Term
ARDS clinical manifestations |
|
Definition
Hx or recent triggering event, suddent severe dyspnea, tachypnea, tachycardia, hypotension, low PaO2, dec. LOC, crackles, rhonchi, frothy secretions
(lungs can sound clear becuase they are so full of fluid) |
|
|
Term
|
Definition
ABG's: dec. PaO2, inc. PCO2, dec. PH
CXR: white fluffy infiltrates
Va/Q shunt |
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|
Term
|
Definition
address the cause
balance F and E
maintain cardiac output-vasopressors
ventilator with PEEP (positive and expiratory pressure)
prone posistion |
|
|
Term
ARDS potential complications |
|
Definition
dysrhythmias, O2 tox, pneumothorax, renal failure, GIB(GI Bleed), sepsis, DIC(Tx heparin) |
|
|
Term
Infant respiratory distress syndrome |
|
Definition
respiratory distress from surfactant deficiency and immature thorax development |
|
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Term
|
Definition
prem. infant(<32 wks) has dec. surfactant-->dec. alveolar compliance
prem. infant-->soft compliant chest-->draws in upon inspiration-->dec. intrathoracic pressure
prem. infant-->immature pulmonary capillaries--> hypoxemia |
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|
Term
|
Definition
dec. alveolar compliance + dec. intrathoracic pressure-->progressive atelectasis--> reversion to circulation from foramen ovale to ductus arteriosus (R to L shunt)-->hypoxemia-->pulmonary vasoconstriction-->inc. PVR
hypoxemia-->anaerobic metabolism of lactic acid-->metabolic acidosis-->pulmonary vasoconstriction
Cellular damage, fluid administration, high levels of FiO2-->inc. cappilary perm.-->pulmonary edema
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|
|
Term
IRDS clinical manifestations |
|
Definition
often normal color and breathing at birth, within a few hours tachypnea (60-120), accessory muscle use, paradoxical respiration, hypotension, dec. breath sounds, oliguria, bradycardia, frothy sputum, expiratory grunt |
|
|
Term
|
Definition
ABG: dec. PaO2, dec. PH
CXR: diffuse whiteout |
|
|
Term
|
Definition
Balance F and E
Ventilator with PEEP with as low O2 as possible(high O2 will damage eyes)
exogenous surfactant (bottle?)
minimal handling
controlled temp |
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|
Term
IRDS potential complications |
|
Definition
Retinal fibroplasia, pneumothorax |
|
|
Term
|
Definition
presence of air in pleural space that inhibits lung expansion |
|
|
Term
closed pneumothorax pathogenesis |
|
Definition
respiratory structure rips open(not from outside)-->pleural viscera torn-->air escapes from airway-->seal between visceral and parietal pleura broken-->lung collapses |
|
|
Term
open pneumothorax pathogenesis (sucking chest wound) |
|
Definition
open hole in chest wall-->parietal pleura is torn-->seal between visceral and parietal pleura broken-->lung collapses-->mediastinal flutter-->severe cardiopulmonary compromise |
|
|
Term
|
Definition
heart is pushed to one side on inspiration and swings back on expiration
(seen with open pneumothorax) |
|
|
Term
tension pneumothorax pathogenesis |
|
Definition
closed or open pneumothorax-->seal between visceral and parietal pleura broken-->lung collapses--air enters pleural space during inspiration and is trapped during expiration-->mediastinal shift (mimics cardiac tamponade)-->compression of contralateral lung, vena cava, aorta, heart-->death
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|
|
Term
clinical manifestations of mediastinal shift |
|
Definition
severe tachycardia, hypotension, tracheal shift, neck vein distension, SQ emphysema (air trapped under skin) |
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|
Term
clinical manifestations of pneumothorax |
|
Definition
tachycardia, decreased/hyperresonant (big, empty space) breath sounds on affected side, CP, dyspnea |
|
|
Term
|
Definition
CXR: collapsed lung, shifts in tension pneumothorax
other tests rare |
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Term
|
Definition
minor: symptom control only
dressing on open pneumothorax can create tension pneumothorax
insertion of chest tube
pleurodesis for collapsed lung (talcom powder)
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|
|
Term
|
Definition
pathological collection of fluid or pus in pleural cavity as a result of a disease process |
|
|
Term
pleural effusion pathogenesis |
|
Definition
1. inc. hydrostatic pressure of plasma(heart failure?)
2. dec. oncotic pressure of plasma(cirrhosis-low albumin)
3. inc. cappillary permeability(pancreas self digests, dumps gastric juices and destroys capillaries)
4. impaired lymphatic drainage |
|
|
Term
pleural effusion etiologies |
|
Definition
renal failure/nephrotic syndrom(lose protien in urine), heart failure, cirrhosis, myxedema, pancreatitis, pulmonary embolism, malignancy, infection, hemothorax, chylothorax |
|
|
Term
pleural effusion clinical manifestations |
|
Definition
pleuritic pain worsening with inspiration, dry cough, dec. chest wall mov't, dec. breath sounds, dec. tactile fremitus (vibration when someone speaks) |
|
|
Term
pleural effusion diagnostics |
|
Definition
CXR
CT/US
analysis of pleural fluid from thoracentesis |
|
|
Term
|
Definition
thoracentesis
chest tube drainage
treat the underlying cause |
|
|
Term
|
Definition
abnormal accumulation of fluid in the alveolar sacs and surrounding intersitium |
|
|
Term
pulmonary edema pathogenesis |
|
Definition
hydrostatic pressure of pulmonary capillaries overwhelms lymphatic drainage of the pulmonary interstitium |
|
|
Term
pulmonary edema etiologies |
|
Definition
cardiogenic: LV failure, MV stenosis, cardiogenic shock, cardiomyopathy, HTN
Noncardiogenic: fluid overload, aspiration of gastric contents, barotraumas(?), near drowning(fluid breathed in washes away surfactant, lung collapses), hypoalbinemia, O2 tox, ARDS, high altitudes, CNS imbalance |
|
|
Term
pulmonary edema clinical manifestations |
|
Definition
coughing thin, often pink, frothy sputum
severe dyspnea, tachypnea, thready tachcardia, severe orthopnea, crackles, wheezes, signs of R sided heart failure |
|
|
Term
pulmonary edema diagnostics |
|
Definition
ABG: dec. SaO2 (plummets), dec PaO2, resp. alkalosis
CXR: whiteout
|
|
|
Term
|
Definition
correct hypoxemia: high FiO2, intubation and ventilation
reduce preload: fowlers, diuretics, NTG
reduce afterload: antihypertensives (ACE inhibitors), morphine(slows SNS)
treat underlying cause |
|
|
Term
|
Definition
inflammation of alveoli and interstitium |
|
|
Term
|
Definition
aspiration of oropharyngeal secretions
inhalation of infection agent
contamination from systemic circulation |
|
|
Term
normal pulmonary defense mechanisms |
|
Definition
coughing
sneezing
cilia (smoking paralyzes)
immune defenses |
|
|
Term
|
Definition
microbial agent inters lung-->agent multiplies in alveoli septa and spaces--> pulmonary infammation-->inflammatory cells invade alveolar septa-->alveoli fill with liquid exudate-->exudate consolidates and resists clearance-->dec. gas exchange |
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|
Term
|
Definition
|
|
Term
pneumonia clinical manifestations |
|
Definition
fever, crackles, bronchial breath sounds, chills, cough, purulent sputum, older adult may present with mental status changes and dehydration.
viral pneumonia presents fever, coryza(head congestion), hoarseness, wheezes, rales |
|
|
Term
|
Definition
CXR: white patches
sputum gram stain and culture |
|
|
Term
|
Definition
antibiotics
fluid and electrolyte balance
O2, bronchodilators
pulmonary clearance: IS ambulate |
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