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Pathophysiology - Definitions 2
Inflammation Definitions 2
13
Medical
Undergraduate 2
04/16/2012

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Cards

Term
Definition of Rolling
Definition
tumbling of WBCs along endothelial surface
Term
Definition of Adhesion
Definition
firm adhesion of wbcs to endothelial surface
Term
Definition of Pavementing
Definition
lining of adhered WBCs to endothelial surface
Term
Definition of Transmigration
Definition

also known as diapedesis

 

WBCs move across the endothelium

Term
Definition of Chemotaxis
Definition
process by which leukocytes emigrate in tissues toward the site of injury
Term
Definition of Exogenous Chemotatic Agent
Definition
bacterial products
Term
Definition of Endogenous Chemotactic Agent
Definition
C5a, leukotrin B4, IL-8
Term
Definition of Vasocontriction
Definition

short period of constriction of precapillary arterioles around injury area

 

length of time varies on degree of injury

Term
Definition of Vasodilation
Definition

greater flow of blood into an area bringing phagocytic cells and plasma proteins to site of injury

 

increases hydrostatic pressure forcing fluid out of blood vessels

Term
Definition of Vascular Permeability
Definition

allows for movement of fluid and plasma proteins from vascular to intersitium

 

most common mechanism is the formation of endothelial gaps in venules

Term
Definition of Complement
Definition
stimuli for degradation and initiation of mast cells
Term
Definition of Anaphylatoxic
Definition
inappropriate swelling of immune response
Term
Definition of Cytokines
Definition

stimuli for degradation of mast cells

 

induce synthesis of adhesion molecules on endothelium

 

act on hypothalamus to increase set point as part of fever

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