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conduct information toward the cell body |
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carries impulses away from cell body |
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PNS - Schwann cells CNS - oligodendrocytes, astrocytes (astroglia), microglia, ependymal |
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produce the myelin sheath = rapid conduction of nerve impulses |
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form the myelin (multilayered around several axon = increase velocity of nerve conduction |
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largest and most numerous - form network, facilitate communication, involved with scar tissue in the brain (gliosis) |
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small, phagocytic - clean up debris |
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lining of neural tube cavity, ventricular system (choroid plexus - production of CSF) |
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nervous tissue metabolic requirement |
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15% of resting cardiac output 20% of it's oxygen |
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functional importance of ion channels |
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they change the polarity of the cell - stimulating the action potentials (communication between neurons) |
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phases of action potential |
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resting membrane potential (-90mV) depolarization (+30 to +45mV) repolarization |
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-60mV; when reached opens ion channels (all or nothing, fully open or fully closed) |
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resting membrane potential |
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-90mV; polarized (pos in/ neg out of cell) but no electrical activity - not transmitting impulses |
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+30 to +45mV; sodium channels open = rapid inflow of sodium ions that generate the electrical impulse |
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close sodium channels, open potassium channels = efflux of potassium and return of resting membrane potential |
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structures that permit communication between neurons |
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consist of gap junctions between adjacent cells that allow action potentials to move rapidly from one cell to another |
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involve special presynaptic and postsynaptic structures, separated by a synaptic cleft. They rely on chemical messengers - released from presynaptic neuron - cross synaptic cleft - interact with receptors of postsynaptic neuron |
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chemical messengers that control neural function; they interact with cell membrane receptors to selectively cause excitation or inhibition of action potentials |
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3 major types of neurotransmitters |
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amino acids (glutamic acid and GABA) peptides (endorphins and enkephalins) monoamines (epinephrine and norepinephrine) |
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chemical messengers that react with membrane receptors to produce slower and longer-acting changes in membrane permeability |
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growth factors - released from presynaptic terminals - required to maintain the long-term survival of postsynaptic neurons |
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forebrain controls the brain stem, the brain stem controls the spinal cord |
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connects neighboring segments contains neurons - reticular activating system reticular formation |
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reticular activating system responsible for regulating arousal and sleep wake transitions |
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site of many important spinal cord and brain stem reflex circuits |
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fibers reach to the brain stem longitudinal communication between more distant segments of nervous system; track systems for sensation and movement |
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pathways for bladder control and fine motor skills develop by fifth year of life become functional in infancy and childhood, very delicate and discriminate function |
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medulla oblongata, cerebellum, and pons gives rise to cranial nerves V-XII controlling viscera, hearing, facial, and mouth/throat functions aka brain stem |
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cerebral peduncles, cerebral aquaduct, superior colliculi, inferior colliculi gives rise to cranial nerves III and IV controlling eye movement |
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thalamus, hypothalamus, cerebrum gives rise to cranial nerves I and II for smell and sight |
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functions of the hindbrain |
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reflex centers for heart and respiration rates, coughing swallowing, vomiting, etc. cerebellum allows fine motor coordination |
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functions of the midbrain |
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cerebral peduncles carry nerve fibers from the cerebrum to the hindbrain cerebral aqueduct lets CSF drain from the 4th ventricle inside the cerebrum superior colliculi control reflex eye movements inferior colliculi control reflex reactions to sound |
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functions of the forebrain |
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thalamus "switchboard" or relay station for impulses going to and coming from the cerebrum hypothalamus homeostatic control |
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frontal lobe: motor, anticipation parietal lobe: somatosensory temporal lobe: hearing, memory occipital lobe: vision limbic system: emotional |
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2 layers inner layer separates the cerebral hemispheres venous blood drains out of the brain in a sinus bridging veins carry blood from the brain across the inner layer of the dura mater to the sinus sinus also collects CSF |
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lies just beneath dura mater waterproof CSF lies under arachnoid to cushion the brain villi (extensions of arachnoid) poke through the inner layer of the dura mater into the sinuses to let CSF drain into the sinuses |
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lies right on the surface of the brain holds the cerebral arteries in place |
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meninges (system of membranes the envelope the CNS) and meningeal spaces |
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epidural space: meningeal arteries dura mater: subdural space: bridging veins arachnoid: subarachnoid space: cerebral arteries, CSF pia mater |
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leaks out of capillaries inside the brain's hollow ventricles (composition controlled by the blood-brain barrier) - passes out an opening below the cerebellum - circulates around the brain and spinal cord in the subarachnoid space - passes through arachnoid villi into blood in the dural sinuses and is returned to the heart |
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catecholamines epinephrine, norepinephrine, dopamine attach to adrenergic receptors |
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sympathetic parasympathetic |
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acetylcholine attaches to cholinergic receptors |
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neurotransmitters for sympathetic postganglionic neurons |
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norepinephrine and epinephrine |
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neurotransmitter for sympathetic: preganglionic parasympathetic: preganglionic and postganglionic |
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adrenergic neurotransmitters |
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synthesized in the sympathetic system attach to adrenergic receptors neurotransmitter is removed from synapse by reuptake or degraded by enzymes |
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alpha 1: constrict blood vessels alpha 2: negative feedback to stop neurotransmitter release beta 1: speed and strengthen heart beta 2: bronchodilation |
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cholinergic neurotransmitter - acetylcholine |
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released from parasympathetic system from motor neurons attaches to cholinergic receptors neurotransmitter is removed from the synapse by acetylcholinesterase |
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nicotinic: excite skeletal muscle cells muscarinic: slow heart, stimulate GI tract, vasodilate |
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efferent (away from CNS) motor |
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