Term
| STATE 3 DIF BTWN INFLAMMATION AND IMMUNITY |
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Definition
1. INFLAMMATION
A NONSPECIFIC BODY DEFENSE RESPONSE TO ANY TISSUE INJURY, WHICH MAY BE CAUSED, BY CHEM, PHSYICAL AGENT, OR TRAUMA, ECT.
IT INVOLVES NEUTROPHILS AND MACROPHAGES AS PART OF CELLULAR RESPONSE AND CHEM MEDIATORS LIKE HISTAMINE AND PROSTOGLANDINS W/ VARIOUS BIOLOGIC EFFECTS.
2. IMMUNITY
IS A SPECIFIC HOST DEFENSE RESPONSE TO "FOREIGN" (NONSELF) ANTIGENS.
IT INVOLVES SPECIFIC (T AND B LYMPHOCYTES) AND HUMORAL (ANTIBODIES) COMPONENTS AND MEDIATORS (e.g. COMPLEMENT)
IT VARIES DEPENDING ON THE NATURE OF THE ANTIGENIC STIMULUS (IMMEDIATE AND DELAYED HYPERTENSIVITIES),
(PG 46; CH 1-2) |
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Term
WHAT IS A CELL SURFACE ANTIGEN?
WHY IS IT IMPORTANT? |
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Definition
CELL SURFACE ANTIGEN-UNIQUE PROTEIN OR GLYCOPROTEIN CONGFIGURATION THAT IS A DISTINCTIVE MARKER FOR THE RECOGNITION OF A CELL BY THE IMMUNSE SYS.
THEY PROVIDE THE MEANS BY WHICH THE IMMUNSE SYS DISTINGUISHES SELF FROM NONSELF.
IMPORTANT BC:
PROVIDES FOR THE DETECTION AND ID OF "NONSELF" BY THE IMMUNSE SYS.
THIS DIFFERENTIATION UNDERLIES THE HOST DEFENSE AGIANST INFECTION AND OTHER FORIEGN ANTIGENS, AND IT FORMS THE BASIS FOR SELECTION OF COMPATIBLE ORGANS AND TISSURE FOR TRANSPLANTATION.
(PG 46-47) |
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Term
WHAT ARE HUMAN LEUKOCYTES ANTIGENS (HLA'S)?
WHAT IS THE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC)? |
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Definition
| THE MHC CELL MEMBRANE ANTIGENS ON HUMAN LEUKOCYTES THAT DETERMINE "SELF" AND SERVE AS THE BASIS FOR IDING HISTOCOMPATIBLE CELLS AND TISSUES FOR TRANSPLANTATION, INCLUDING BLOOD TRANSFUSION. THESE ANTIGENS REPRESENTING "SELF" ARE PRESENT ON AND INDIVIDUALS CELL MEMBRANES |
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Term
CHEMICAL MEDIATORS PLAY AN IMPORTANT ROLE IN BOTH INFLAMMATION AND IMMUNITY. ID THE SOURCE AND EFFECTS OF THE MAJOR CHEM MEDIATORS:
HISTAMINE |
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Definition
SOURCE:
MAST CELLS AND BASOPHILS
EFFECTS:
VASODIALATION AND INCREASED VASCULAR PERMEABILITY, CONTRACTION OF BRONCHIOLAR SMOOTH MUSCLE
PRURITIS |
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Term
CHEMICAL MEDIATORS PLAY AN IMPORTANT ROLE IN BOTH INFLAMMATION AND IMMUNITY. ID THE SOURCE AND EFFECTS OF THE MAJOR CHEM MEDIATORS:
PROSTOGLANDINS |
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Definition
SOURCE:
GOUPS OF LIPIDS SYNTHESIZED IN MAST CELLS
EFFECTS:
VARIOUS EFFECTS FROM CAUSING:
INFLAMMATION
VASODIALATION
INCREASED CAPILLARY PERMEABILITY
PAIN |
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Term
CHEMICAL MEDIATORS PLAY AN IMPORTANT ROLE IN BOTH INFLAMMATION AND IMMUNITY. ID THE SOURCE AND EFFECTS OF THE MAJOR CHEM MEDIATORS:
CYTOKINES
(LYMPHOKINES, MONOKINES, INTERLEUKINS, INTERFERON) |
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Definition
SOURCE:
T-LYMPHOCYTES AND MACROPHAGES
EFFECTS:
INCREASE IN PLASMA PROTEINS, ESR
STIMULATE ACTIVATION AND PROLIFERATION OF B AND T CELLS AND COMMUNICATION BTWN CELLS (MESSENGERS)
INDUCE FEVER, LEUKOCYTOSIS, AND CHEMOTAXIS |
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Term
CHEMICAL MEDIATORS PLAY AN IMPORTANT ROLE IN BOTH INFLAMMATION AND IMMUNITY. ID THE SOURCE AND EFFECTS OF THE MAJOR CHEM MEDIATORS:
LEUKOTRIENES |
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Definition
SOURCE:
GROUP OF LIPIDS DERIVED FROM MAST CELLS AND BASOPHILS
EFFECTS:
CONTRACTION OF BRONCHIOLAR SMOOTH MUSCLE
VASODIALATION AND INCREASED CAPILLARY PERMEABILITY
CHEMOTAXIS |
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Term
CHEMICAL MEDIATORS PLAY AN IMPORTANT ROLE IN BOTH INFLAMMATION AND IMMUNITY. ID THE SOURCE AND EFFECTS OF THE MAJOR CHEM MEDIATORS:
KININS
(BRADYKININ) |
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Definition
| ACTIVATION OF PLASMA PROTEIN (KINOGEN; e.g. BRADYKININ) |
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Term
CHEMICAL MEDIATORS PLAY AN IMPORTANT ROLE IN BOTH INFLAMMATION AND IMMUNITY. ID THE SOURCE AND EFFECTS OF THE MAJOR CHEM MEDIATORS:
COMPLEMENT |
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Definition
SOURCE:
GROUP OF PROTEINS CIRCULATING IN THE BLOOD STREAM
ACTIVATED BY ANTIGEN-ANTIBODY RXNS ON CELL SURFACE.
EFFECTS:
RELEASE OF CHEM MEDIATORS PROMOTING:
INFLAMMATION
CHEMOTAXIS
PHAGOCYTOSIS
CELL MEMBRANE DAMAGE
(e.g. HEMOLYSIS) |
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Term
SEVERL OF THE CHEMICAL MEDIATORS HAVE OVERLAPPING EFFECTS. ID WHICH ONES ARE RESPONSIBLE FOR EA OF THE FOLLOWING CELLULAR OR BODY RESPONSES:
VASODIALATION |
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Definition
1. HISTAMINE
2. PROSTOGLANDINS
3. KININS
4. LEUKOCYTES |
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Term
SEVERL OF THE CHEMICAL MEDIATORS HAVE OVERLAPPING EFFECTS. ID WHICH ONES ARE RESPONSIBLE FOR EA OF THE FOLLOWING CELLULAR OR BODY RESPONSES:
INCREASED CAPILLARY PERMEABILITY |
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Definition
1. HISTAMINES
2. PROSTOGLANDINS
3. LEUKOTRIENES |
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Term
SEVERL OF THE CHEMICAL MEDIATORS HAVE OVERLAPPING EFFECTS. ID WHICH ONES ARE RESPONSIBLE FOR EA OF THE FOLLOWING CELLULAR OR BODY RESPONSES:
CHEMOTAXIS |
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Definition
1. CYTOKINES
2. LEUKOTRIENES
3. COMPLEMENT |
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Term
SEVERL OF THE CHEMICAL MEDIATORS HAVE OVERLAPPING EFFECTS. ID WHICH ONES ARE RESPONSIBLE FOR EA OF THE FOLLOWING CELLULAR OR BODY RESPONSES:
PAIN |
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Definition
1. PROSTOGLANDINS
2. KININS |
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Term
SEVERL OF THE CHEMICAL MEDIATORS HAVE OVERLAPPING EFFECTS. ID WHICH ONES ARE RESPONSIBLE FOR EA OF THE FOLLOWING CELLULAR OR BODY RESPONSES:
CONTRACTION OF BRONCHIOLAR WALL/BRONCHOSPASM |
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Definition
1. HISTAMINES
2. LEUKOTRIENES |
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Term
SEVERL OF THE CHEMICAL MEDIATORS HAVE OVERLAPPING EFFECTS. ID WHICH ONES ARE RESPONSIBLE FOR EA OF THE FOLLOWING CELLULAR OR BODY RESPONSES:
PROLIFERATION OF LEUKOCYTES |
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Definition
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Term
SEVERL OF THE CHEMICAL MEDIATORS HAVE OVERLAPPING EFFECTS. ID WHICH ONES ARE RESPONSIBLE FOR EA OF THE FOLLOWING CELLULAR OR BODY RESPONSES:
PRURITIS |
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Definition
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Term
SEVERL OF THE CHEMICAL MEDIATORS HAVE OVERLAPPING EFFECTS. ID WHICH ONES ARE RESPONSIBLE FOR EA OF THE FOLLOWING CELLULAR OR BODY RESPONSES:
FEVER |
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Definition
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Term
THE FOLLOWING CELLS ARE INVOLVED IN IMMUNITY. ID THE ROLE OF EA:
MACROPHAGES |
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Definition
PHAGOCYTOSIS:
FORIEGN ANTIGEN RECOGNITION |
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Term
THE FOLLOWING CELLS ARE INVOLVED IN IMMUNITY. ID THE ROLE OF EA:
NATURAL KILLER (NK) CELLS |
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Definition
DESTOY:
FOREIGN CELLS
VIRUS-INFECTED CELLS
CANCER CELLS |
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Term
THE FOLLOWING CELLS ARE INVOLVED IN IMMUNITY. ID THE ROLE OF EA:
CYTOTOXIC OR KILLER T CELLS |
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Definition
| DESTROY ANTIGENS, CANCER AND VIRUS-INFECTED CELLS |
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Term
THE FOLLOWING CELLS ARE INVOLVED IN IMMUNITY. ID THE ROLE OF EA:
HELPER T CELLS (T4 OR CD4) |
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Definition
1. ACTIVE B AND T CELLS
2. LIMIT IMMUNE RESPONSE |
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Term
THE FOLLOWING CELLS ARE INVOLVED IN IMMUNITY. ID THE ROLE OF EA:
MEMORY T CELLS |
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Definition
1. REMEMBER ANTIGEN
2. STIMULATE IMMUNE RESPONSE UPON SUBSEQUENT EXPOSURE (SECONDARY RESPONSE) |
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Term
THE FOLLOWING CELLS ARE INVOLVED IN IMMUNITY. ID THE ROLE OF EA:
SUPRESSOR T CELLS (T8) |
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Definition
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Term
THE FOLLOWING CELLS ARE INVOLVED IN IMMUNITY. ID THE ROLE OF EA:
PLASMA CELLS |
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Definition
| PRODUCE SPECIFIC ANTIBODY |
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Term
THE FOLLOWING CELLS ARE INVOLVED IN IMMUNITY. ID THE ROLE OF EA:
B MEMORY CELLS |
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Definition
| SECONDARY ANTIBODY RESPONSE |
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Term
| WHICH TYPE(S) OF CELLS PLAY A ROLE IN BOTH INFLAMMATION AND IMMUNITY? |
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Definition
1. MONOCYTES
2. MACROPHAGES
3. BASOPHILS |
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Term
| WHICH CELLS PARTICIPATE IN BOTH CELLULAR AND HUMORAL IMMUNITY? |
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Definition
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Term
| LIST THE 5 CLASSES OF ANTIBODIES OR IMMUNOGLOBULINS, AND STATE THE FUNCTIONS OF EA. |
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Definition
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Term
| EXPLAIN HOW ANTIBODIES EXERT THEIR EFFECTS. |
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Definition
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Term
| WHAT IS THE TIME FRAME BTWN EXPOSURE TO AN ANTIGEN AND THE APPEARANCE OF IMMUNOGLOBULINS IN THE SERUM? |
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Definition
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Term
| EXPLAIN THE RATIONALE FOR "BOOSTERS"? |
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Definition
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Term
| EXPLAIN WHY INDIVIDUALS MAY CONTRACT INFECTIONS SUCH AS COLDS, INFLUENZA, AND STDS REPEATEDLY. |
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Definition
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