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pathology
exam 1
29
Nursing
Undergraduate 1
06/25/2009

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Term
what is cellular atrophy?
Definition
decrease in the size of a cell due to decreased workload
Term
what is cellular hyperplasia?
Definition
increase in cell numbers. occurs in cells that are capable of mitotic division ex. epithelial .responce to a stimulus ex. wound healing
Term
examples of cellular injury
Definition
hypoxia(deprives cell of o2), physical agents, chemical agents, bioligic agents(virus), radiation, nutrition imbalance
Term
what is cellular hypertrophy?
Definition
increase in cell size due to increase in workload
Term
what is cellular dysplasia?
Definition
deranged cell growth with various shapes and sizes. could be associated with inflammation or irritation. can be precursor to cancer
Term
What is cellular metaplasia
Definition
reversable change where one type of adult cell is replaced by another adult cell type. occurs to chronic irritation or inflammation
Term
What is hypoxia?
Definition
a cell that is deprived of oxygen and interrupts metabolism and ATP production.caused by amnt of O2 in the air, respitory disease, anemia ect
Term
What is necrosis?
Definition
dead cells, rotten tissue. nuclease most noticed, loose function of dead area, enzymes produced.
Term
What is ischemia?
Definition
decreased blood supply due to functional constriction or obstruction of a blood vessel
Term
Define apoptysis
Definition
cell suicide. eliminates cells that are worn out, have been overproduced or have genetic damage. enzyme degrade the cell to make it a target for phagocytosis
Term
What cancer causes deaths in women?
Definition
#1 lung #2 breast #3 colon/rectum
Term
what cancer causes deaths in men?
Definition
#1 lung #2 prostate #3 colon/rectum
Term
What are the warning signs of cancer?
Definition
change in bowel or bladder, lumps, sore throat, chronic indigestion, swallowing problems, wound that doesnt heal, change in mole or wart
Term
What is chemotherapy?
Definition
systematic treatment that enables drugs to kill rapidly proliferating cells. supress bone marrow leading to anemia, neutropenia causes depressed imuune function, thrombocytopenia leads to bleading. also nausea , fatigue, ect
Term
Radiation Therapy
Definition
ionizes radiation to molecules immediately killing cells or delaying cell cycle. dangerous to bone marrow, rapidly proliferating cells, and mucosal lining of gi tract. infection, bleeding, anemia nausea and vomiting and sublethal injury.
Term
anaphylactic shock
Definition
systemic, life threatening hypersensitivity reaction characterized by widespread vasodilation that leads to a fall in blood pressure, airway constriction. Obstruction of upper airway is biggest concern.
Term
what lab tests are used to identify autoimmune disorders?
Definition
serologic testing- antibodies against tissue antigens or cell components. also clinical findings help diagnose
Term
what are common infections that those with AIDS aquire
Definition
pneumonia, TB-examination of sputum,bronchoscopy, thrush, herpes, aids dementia
Term
HIV
Definition
retrovirus that carries its genetic material on RNA. Replication occurs in 8 steps.
Term
what occurs during inflammation
Definition
earliest reaction. redness, swelling,pain, heat, discomfort
Term
manifestations of inflammation
Definition
vasodialation, increase of capillary permeability, influx of inflammatory cells(neutrophils) = some times fever.
Term
cellular changes of acute inflammation
Definition
vasodialation, increased capillary permeability, influx inflammatory cells
Term
celluar changes of chronic inflammation
Definition
due to infiltration with macrophages, lymphocytes and fibroblasts lead to persistant inflammaiton, fibroblast proliferation and scar formation
Term
how does autoimmune disease happen
Definition
it is not known, but both inheritance of genes and enviornmental factors play a part. gender also plays a role suggesting estrogen.
Term
how does inflammation protect the body
Definition
vasoconstriction, vasodialation, leukocytes,
Term
what is the patho of disk
Definition
Term
what is a hurniated disc
Definition
the nucleus puoposus is squeezed out of place and herniate through the annulus fibrosus
Term
how can u asses for carpal tunnel syndrome and explain the pathology?
Definition
characterized by pain and numbness of the thumb and first two and one half digits of the hand, pain in the wrist and hand which worsens at night. Compression of the median nerve by the transverse carpal ligament
Term
Guillain Barre Syndrome
Definition
acute immune mediated polyneuropathy characterized by rapidly progressive limb weekness and loss of tendon reflexes, flaccid paralysis. sometimes a acute influenza like illness before symptoms. facial flushing, sweating and urinary retention, pain.rapid development of ventilatory failure and threaten circulatory function
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