Term
Vitiligo
a) Pigment loss
b) Excess pigment
c) Pigment Cell proliferation |
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Definition
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Term
Freckle
a) Pigment loss
b) Excess pigment
c) Pigment Cell proliferation |
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Definition
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Term
Melasma
a) Pigment loss
b) Excess pigment
c) Pigment Cell proliferation |
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Definition
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Term
Lentigo
a) Pigment loss
b) Excess pigment
c) Pigment Cell proliferation |
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Definition
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Term
Melanocytic Nevi
a) Pigment loss
b) Excess pigment
c) Pigment Cell proliferation |
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Definition
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Term
Malignant Melanoma
a) Pigment loss
b) Excess pigment
c) Pigment Cell proliferation |
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Definition
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Term
| A melanocytic nevus is a nevus of ___ origin that migrates to the skin from the ____ during embryonic life. ___ nevi aggregate along the dermal-epidermal junction. ____nevi drop off into the dermis forming nests of elongated cells. ____nevi composed of elongated cells resembling nueral tissue. Maturation is loss of ____ activity and aquisition of ____ activity. Associated with ___ & ___ mutations. |
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Definition
| Melanocytic, Nural crest, Junctional, Compound, Intradermal, Tyrosinase, Cholinesterase, BRAF and NRAS |
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Term
| Macule or slightly elevated plaque with certain variation in color. This is a _____ the histopathology is _____. |
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Definition
| Dysplastic Nevus, Atypical Melanocytes |
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Term
Name the lesion:
Large pebbly surface, variegated brown macule with fuzzy margins and oval but symmetrical shape. |
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Definition
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Term
Name the lesion:
Bridging of melanocytic nests between adjacent rete ridges |
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Definition
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Term
| What are the ABCDE characteristics of Melanoma? |
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Definition
| Asymmetry, Border irregularity, Color variation, Dimater >6mm, Elevation |
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Term
| Malignant Melanoma displays and ___growth pattern |
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Definition
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Term
What layer does each Clark Level of Invasion correspond to?
I
II
III
IV
V |
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Definition
I-Epidermis
II-Papillary Dermis
III- Lower Papillary Dermis
IV-Reticular Dermis
V- Subcutaneous fat |
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Term
| What are the two methods of staging of Malignant Melanoma? |
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Definition
| Clark Level of Invasion, Breslow Thickness |
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Term
For each Prognostic Criteria of Melanoma what indicates a favorable prognosis?
1) Depth of invasion
2) Mitotic activity
3) Regression
4) Tumor infiltrating lymphocytes at baseof vertical growth
5)Gender
6)Location
7)Lymph nodes metastasis |
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Definition
1) 2) Low
3)Absent
4)Numerous
5)Female
6)Limbs
7)Absent |
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Term
Name the Melanoma Variant:
After appearance immediately proceeds to vertical growth, poor prognosis |
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Definition
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Term
Name the Melanoma Variant:
Palms, soles & subungual area, any age, black-skinned people, |
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Definition
| Acral lentiginous melanoma |
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Term
| Name the Melanoma Variant: Atypical melanocytes at the dermoepidermal interface, irregular, angular & hyperchromatic nuclei, large flat pigmented patch on the sun exposed skin of the elderly |
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Definition
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Term
Name the Melanoma Variant:
Exhibits radial growth |
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Definition
| Superfical spreading melanoma |
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Term
A 70 year old woman presents with facial discoloration. The patient is observed to have a flat, pigmented lesion on the atrophic sun damaged skin. Which of the following is the most likely diagnosis?
a) Acral lentiginous melanoma
b) Alopecia
c) Lentigo maligna
d) Mucosal lentiginous melanoma
e) Nodular melanoma |
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Definition
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