Term
|
Definition
| hard, fixed, and painless |
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|
Term
| Oral contraceptives reduce the risk of ? |
|
Definition
|
|
Term
| Acute mastitis by Strep. causes what ? |
|
Definition
| Whole breast affected and heals w/o scar |
|
|
Term
| Most common benign tumor of breast and is described as "mouse in the beast" ? |
|
Definition
|
|
Term
|
Definition
| Loose edematous myxoid fibroblastic stroma + ductlike epithelial lined spaces |
|
|
Term
| Phylloides tumor (leaf-like) spreads via ? |
|
Definition
|
|
Term
| BRCA 1 and BRCA 2 genes are located on what chromosomes ? |
|
Definition
BRCA 1 - Chromosome 17
BRCA 2 - Chromosome 13 |
|
|
Term
| Most breast cancers are located in ? |
|
Definition
|
|
Term
| Breast cancer invade what 3 lymph nodes ? |
|
Definition
A I S
Axillary , then internal mammary , then supraclavicular |
|
|
Term
| What type of ductal carcinoma in-situ subtype has a necrotic center that squeezes out material like a toothpaste ? |
|
Definition
|
|
Term
| Characteristics of medullary carcinoma of breast ? |
|
Definition
On histo has large sheets of large oval cells, and little stroma
Structure similar to dysgerminoma ovary, and seminoma testis |
|
|
Term
| What breast carcinoma shows Indian file and bull's eye pattern on histo ? |
|
Definition
| Infiltrating lobular carcinoma |
|
|
Term
| Histo of Paget's disease of breast ? |
|
Definition
| See Paget's cells (large hyperchromatic nucleus with halo) |
|
|
Term
| Toker cells seen in what cancer ? |
|
Definition
| Paget's Disease of the Nipple / Breast |
|
|
Term
| ER+ / PR+ breast tumors respond to ? |
|
Definition
|
|
Term
| Herceptin (Trastuzumab) is not useful against metastatic disease b/c ? |
|
Definition
| It cannot cross blood brain barrier |
|
|
Term
| Indicators for good prognosis in breast cancer ? |
|
Definition
Tumor < 2cm
No axillary lymph node involvement
ER +
Lack of aneuploidy
Lack of cathepsin D
Lack of Her 2 neu |
|
|
Term
| Chocolate cysts of ovary are caused by ? |
|
Definition
Endometriosis
Repeated cyclical hemorrhage gives the chocolate color
Consist of endometrial glands + stroma + RBC + hemosiderin |
|
|
Term
| What disease gives you oligomenorrhea, secondary amenorrhea, hirsutism, obesity, and infertility ? |
|
Definition
PCOD or Stein Leventhal Syndrome
Have increase LH and androgens and
decreased FSH
Ultrasound shows bilaterally enlarged ovaries with multiple subcapsular cysts |
|
|
Term
| Problem with treating tumors of ovary is ? |
|
Definition
|
|
Term
| 4 subtypes of Germ Cell tumor of the ovaries ? |
|
Definition
T E D C
Teratoma
Endodermal Sinus Tumor (or Yolk Sac Tumor)
Dysgerminoma
Choriocarcinoma |
|
|
Term
| 3 subtypes of Sex cord stromal tumors of the ovaries ? |
|
Definition
F G S
Fibroma
Granulosa Theca Tumor
Sertoli Leydig tumor |
|
|
Term
| Subtypes of Surface Epithelial Tumors of the ovary ? |
|
Definition
S E M B U M
Serous
Endometriod
Mucinous
Brenner
Undifferentiated
Mixed |
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