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Pathology of Pulmonary Infection
Pulmonary Module
45
Medical
Graduate
10/27/2009

Additional Medical Flashcards

 


 

Cards

Term
What does the word pneumonia mean?
Definition
inflammation of the distal lung
Term
What are the pulmonary defense systems that break down and lead to a suseptability to pneumonia? (5)
Definition

mucociliary apparatus

nasal filtration

dust cells

immunologic (BALT, IgA)

cough reflex

Term
When you lose the ability to cough or have a depressed level of conciousness what are you at risk for which would increase likelihood of developing pneumonia?
Definition
aspiration
Term
What two types of aspiration fluids are most common in causing pneumonia?
Definition

gastric acid

upper respiratory excretion

Term
How does pulmonary edema contribute to the development of pneumonia?
Definition
it allows for an optimal environment for bacteria to grow in
Term
What are the four general routes of bacterial entry in developing pneumonia?
Definition

airway

hematogenous

contiguous

implanted

Term
What type of pneumonia (classified by anatomy) is one in which effects more than one lobe?
Definition
bronchopneumonia
Term
Where does the aspiration in bronchopneumonia usually land histologically, leading to its classic presentation?
Definition
lands in the respiratory bronchiole
Term
Which type of pneumonia is found at the extremes in life (old and young)?
Definition
bronchopneumonia
Term
What type of pneumonia is found in middle aged individuals?
Definition
lobar pneumonia
Term
Which type of pneumonia becomes coonfluent when the organism passes through the pores of Kohn?
Definition
bronchopneumonia
Term
What is empyema?
Definition
collection of pus in the pleural space
Term
How many stages are there of lobar pneumonia and what are they?
Definition

4

congestion

red hepatization

grey hepatization

resolution

Term
What type of pneumonia presents with four classic stages?
Definition
lobar pneumonia
Term
What stage of lobar pneumonia is due to leakage and increased protein, RBC in the alveolar spaces?
Definition
congestion
Term
What is the timeline for the stages of lobar pneumonia?
Definition

congestion (24-48 hrs)

red hepatization (days)

grey hepatization (1 wk)

resolution (1-2 wks, if he/she survives)

Term
What stage of lobar pneumonia is characteristic of PMN infiltrates?
Definition
red hepatization
Term
Why is the third phase of lobar pneumonia grey in color?
Definition
b/c the macrophages ger rid of RBC
Term
What occurs during the resolution phase of  lobar pneumonia?
Definition
breakdown of the consolidation
Term
What pneumonia causing bacteria is gram + cocci and grows in clusters?
Definition
staph
Term
What pneumonia causing bacteria is gram + diplococci?
Definition
strep pneumoniae
Term
What bacteria is the #1 cause of community acquired pneumonia?
Definition
Streptococcus pneumoniae
Term
What virulent factor makes streptococcus pneumoniae so resistant to phagocytosis?
Definition
its capsule
Term
If you have a patient with lobar pneumonia, what is the most likely bacteria causing the pneumonia?
Definition

streptococcus pneumoniae

 

but also know that strept. pneumoniae also still causes bronchopneumonia

Term
Name two common complications of streptococcus pneumoniae?
Definition

emphyema

pleural effusion

Term
Name the four general complications/metastatic infections that streptococcus pneumonia cause?
Definition

MOPS

 

meningitis

ottis media

pneumonia

sinusitis

Term
What clinical setting is staph peumonia most common in?
Definition
nosmocomial
Term
What type of patients do gram negative pneumonias effect and generally what is the mortality rate?
Definition

hospitalized/debilitated patients

 

high mortality

Term
What are the three gram negative pneumonia causing bacterias we discussed?
Definition

Kleibsiella

Pseudomonas

Legionella

Term
What are the 4 A's of Klebsiella Pneumonia?
Definition

Aspiration

Alcoholics

diAbetics

Abcess

 

 

Term
What type of sputum is representative of Klebsiella pneumonia?
Definition
red currant bloody sputum
Term
What types of pneumonias does pseudomonas cause?
Definition

bronchopneumonia due to aspiration

and bactermic

Term
What organism produces necrotic blue/green lesions around vessels?
Definition
Pseudomonas pneumonia
Term
What specific types (4) of patients do you see Psuedomonas Pneumonia in?
Definition

burn patients

Transplant patients

neutropenic

cystic fibrosis

Term
What is true of the timeline of systemic symptoms and respiratory symptoms in legionella pneumonia?
Definition
the systemic symptoms often come before the respiratory symptoms
Term

What type of pneumonia (anatomic classification) does legionella cause?

 

Definition
bronchopneumonia
Term
How you detect legionella pneumonia?
Definition
Dieterle Silver STain
Term
What does leginella pneumonia due within macrophages?
Definition
replicate
Term
What are the pathologic characteristics of atypical pneumonia that make them atypical?
Definition

they dont form exudate (dry cough) with alveoli

they infiltrate the alveoli septa w/o consolidation

 

 

Term
What type of pneumonia can cause ARDS?
Definition
atypical
Term
What is the most common type of atypical pneumonia?
Definition
Mycoplasma
Term
What is the characteristic finding on an XRAY of an lung abcess if it communicates wiht a bronchus?
Definition
air/fluid line
Term
What type of patients do you see pneumocystis jiroveci in?
Definition
immunocompromised
Term
What type of organism is pneumocystis jiroveci?
Definition
fungi
Term
Can you biopsy Pneumocystis jiroveci?
Definition
no you have to look for it in sputum with microscopy
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