Term
| 4 routes of access to CNS |
|
Definition
| hematogenous (most common), direct implantation (skull fracture), sinus/middle ear/tooth infection, retrograde transport (PNS->CNS) |
|
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Term
| hx of N. meningitis, bilateral hemorrhagic infarction of adrenal glands; dx? |
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Definition
| Waterhouse-Friderichsen syndrome |
|
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Term
| most common bugs causing brain abscess |
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Definition
|
|
Term
| development of brain abscess can resolve to __ or progress to __ |
|
Definition
| fibrous capsule or mass lesion |
|
|
Term
| brain abscess causes __ edema |
|
Definition
|
|
Term
|
Definition
| multiple foci of softening |
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|
Term
| pathology of septic embolic |
|
Definition
| hemorrhagic infarction, mycotic aneurysm |
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Term
|
Definition
|
|
Term
| AIDS pt shows biopsy of sheets of macrophages and histiocytes; dx? |
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Definition
|
|
Term
| TB can cause __ hydrocephalus |
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Definition
|
|
Term
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Definition
|
|
Term
| most common fungal meningitis |
|
Definition
|
|
Term
| capsule, narrow-based bud; dx: India Ink, Ag test of CSF |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| aspergillus, mucormycosis, candida, rickettsia |
|
|
Term
| acute angle branching, true septate |
|
Definition
|
|
Term
| right angle branching, non septate |
|
Definition
|
|
Term
| 3 manifestations of neurosyphilis |
|
Definition
| meningovascular, paretic, tabes dorsalis |
|
|
Term
| chronic meningitis at base of brain; BCs, TCs, Heubner arteritis; dx? |
|
Definition
|
|
Term
| brain invasion, psychosis or dementia, gliosis, rod cells; dx? |
|
Definition
|
|
Term
| dorsal nerve root inflammation, degeneration of ascending dorsal columns; dx? |
|
Definition
|
|
Term
| impaired position, pain, DTRs; ataxia; Charcot joints; dx? |
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Definition
|
|
Term
| maculopapular rash on palms and soles spreading centrally; confusion, lethargy, ataxia, seizures; dx? |
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Definition
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|
Term
|
Definition
|
|
Term
| most common cause of focal brain lesions in AIDS pts |
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Definition
|
|
Term
| tropism for Toxoplasma gondii |
|
Definition
| basal ganglia, gray-white junctions |
|
|
Term
| swimming pools, freshwater lakes, infects healthy ppl; invades via cribriform plate; fatal, necrotizing; dx? |
|
Definition
|
|
Term
| most common amoeba in soil; infects immunocompromised; forms granulomas; dx? |
|
Definition
|
|
Term
how do the following bugs access the CNS?
1. herpes
2. rabies
3. EEE
4. measles
5. Naegleria fowlerii |
|
Definition
1. retrograde transport
2. retrograde transport
3. cribriform plate
4. hematogenous
5. cribriform plate |
|
|
Term
| Mucormycosis is most commonly seen in what types of pts? |
|
Definition
| diabetics with ketoacidosis |
|
|
Term
| bacterial meningitis: gross? |
|
Definition
| enlarged brain, pus in subarachnoid space, narrow sulci, engorged blood vessels |
|
|
Term
which bugs are common causes of meningitis in the following age groups?
1. neonates
2. children
3. young adults
4. elderly
5. immunosuppressed |
|
Definition
1. neonates: GBS, Gram negatives, Listeria
2. children: Strep pneumo
3. young adults: Neisseria meningitis
4. elderly: Strep pneumo, Listeria
5. immunosuppressed: Listeria, fungi, TB |
|
|
Term
| risk factors for brain abscess development (6) |
|
Definition
| endocarditis, congenital heart disease, sinusitis, dental extractions, bronchiectasis, immunosuppressed |
|
|
Term
| ring-like lesion on MRI; ddx? |
|
Definition
| metastatic tumors or multiple abscesses |
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