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Pathology - Leukemia Karyotype
Prognostic indicators
13
Medical
Professional
01/27/2007
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Term
t(9;22)(q34;q11)
 Definition
CML; subset of ALL (5% of pediatric and 25% of adult ALL)
Term
t(15;17)(q22;q21)
 Definition
Acute Promyelocytic Leukemia
Term
t(8;21)(q22;q22)
 Definition
AML with maturation; favorable prognosis
Term
t(8;14)(q24;q32)
 Definition
3% of ALL; 90% of mature B-ALL (Burkitt Lymphoma)
Term
t(1;19)
 Definition
5-6% of ALL; low EFS
Term
t(12;21)
 Definition
25% of ALL; high cure rate in children
Term
>50 chromosomes
 Definition
15% of ALL
Term
Trisomy 12, del(11q), del(17p)
 Definition
CLL worse prognosis
Term
del(13q)
 Definition
CLL good prognosis
Term
del(13); t(11;14)
 Definition
MM
Term
del(6)
 Definition
Lymphoplasmacytic Lymphoma
Term
t(14;18)
 Definition
Follicular Lymphoma; subset of Diffuse Large Cell Lymphoma
Term
t(3q27)
 Definition
Diffuse Large B-Cell Lymphoma
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