bronchial smooth muscle hyperplasia

goblet cecll hyperplasia

increased BM thickness

mast on Giemsa stain release vasoactive amine

basophil infiltrate via Leukotriene B4 + eosinophil chemofactor anaphylaxis (ECF-A)

local

Type 1 hypersensitivity

local anaphylaxis

asthma

lymph, plasma, mac, eosinophil infiltrate in intima + tubule

Ab mediate

vessel has intimal thickening with swelling

platelet fibrin thrombi within glomerular capillary

fibrinoid necrosis of vessel

acute rejection of kidney transplant

Type 2, 3, 4.

thickening and fibrosis of artery

interstitial fibrosis

globally sclerotic glomeruli

tubular loss

fibrosis

lymph in pannus

proliferative synovitis

prominent lobule

wireloop lesion

thrombi in glomerulus

fibrinoid necrosis

renal failure -> CHF + pulm. edema + generalized edema/anasarca

diffuse GN by anti-dsDNA

SLE in kidney

organ finding vs. autoantibody

cerebritis

malar/rash/photosensitivity

cytopenia

libman sacks endocarditis/stroke/spontaneous abortion

arteritis

anti-neuronal/ribosomal-P

anti-Ro

anti-blood cell type

anti-phospholipid

anti-dsDNA

Hurthle cell

destructionof thyroglobulin follicle

fibrosis

lymph + germinal center around site

Hashimoto's Thyroditis

Type 2

hemolytic anemia

gloodpasture's syndrome

IDDM

Grave's disease

Hashimoto THyroditis

SLE

RA

arthus

acute serum sickness

local neutrophil

vascular wall destroyed by infultrate cecll/fibrinoid necrosis

rupture of vessel

arthus reaction

type 3. precipitate on wall trigger inflam. rxn that activate neutrophil.