Term
abl :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Oncogene
- Product: Tyrosine kinase
- Tumor: CML |
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Term
c-myc :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Oncogene
- Product: Transcription factor
- Tumor: Burkitt's lymphoma |
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Term
bcl-2 :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Oncogene
- Product: Anti-apoptotic molecule
- Tumor: Follicular and undifferentiated lymphomas |
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Term
erb-B2 :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Oncogene
- Product: Tyrosine kinase
- Tumor: Breast, ovarian, and gastric carcinomas |
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Term
ras :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Oncogene
- Product: GTPase
- Tumor: Colon carcinoma |
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Term
L-myc :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Oncogene
- Product: Transcription factor
- Tumor: Lung tumor |
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Term
N-myc :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Oncogene
- Product: Transcription factor
- Tumor: Neuroblastoma |
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Term
ret :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Oncogene
- Product: Tyrosine kinase
- Tumor: MEN IIA and IIB |
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Term
c-kit :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Oncogene
- Product: Cytokine receptor
- Tumor: Gastrointestinal stromal tumor (GIST) |
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Term
Rb :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Product: Blocks G1-S phase of cell cycle
- Tumor: Retinoblastoma, osteosarcoma |
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Term
p53 :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Product: Blocks G1-S phase of cell cycle
- Tumor: Nearly every cancer, Li-Fraumeni syndrome |
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Term
BRCA1 :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Product: DNA repair protein
- Tumor: Breast and ovarian cancer |
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Term
BRCA2 :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Product: DNA repair protein
- Tumor: Breast cancer |
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Term
p16 :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Tumor: Melanoma |
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Term
APC :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Tumor: Colorectal cancer (associated with FAP) |
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Term
WT1 :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Tumor: Wilms' tumor |
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Term
NF1 :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Tumor: Neurofibromatosis type 1 |
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Term
NF2 :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Tumor: Neurofibromatosis type 2 |
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Term
DPC :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Tumor: Pancreatic cancer |
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Term
DCC :
- Oncogene (gain of function cancers) or Tumor supressor gene?
- Gene product (if any)
- Associated tumor |
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Definition
- Tumor suppressor gene
- Tumor: Colon cancer |
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