Term
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Definition
light to dark pink. polygonal, PTH |
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Term
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Definition
water-clear due to glycogen, acidophilic, packed with mitochondria |
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Term
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Definition
increased renal Ca reabsorption, Vit D kidney conversion, urinary phosphate excretion, GI Ca absorption |
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Term
Most common cause of clinically apparent hypercalcemia |
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Definition
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Term
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Definition
decoy receptor of RANKL which siphons off excess ligand |
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Term
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Definition
activating mutation of RET tyrosine kinase inhibitor |
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Term
Familial hypocalciuric hypercalcemia |
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Definition
autosomal-dominant, decreased Ca sensitivity, calcium-sensing receptor (CASR) on 3q |
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Term
Parathyroid Adenoma Genetics |
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Definition
Pericentric 11q inversion including Cyclin D1 placed near the PTH gene regulator. Also MEN1 (11q13) |
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Term
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Definition
compressed, non-neoplastic capsule, endocrine atypia, abundant water-clear cells |
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Term
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Definition
bizarre and pleomorphic nuclei |
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Term
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Definition
gray-white, irregular masses, invasion is the only true marker |
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Term
Parathyroid Cancer symptoms |
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Definition
Bonen disease, nephrolithiasis, GI disturbances, depression, lethargy, seizures, weakness, fatigue, cardiac manifestations |
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Term
Most common cause of secondary parathyroidism |
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Definition
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Term
Hypoparathyroidism most common cause |
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Definition
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Term
Hypoparathyroid genetic causes |
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Definition
Autoimmune in autoimmune polyendocrine syndrome type 1 (APS1) with AIRE mutation, CASR, familial isolated hypoparathyroidism (FIH) is dominant in precursor gene and recessive with GCM2 |
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Term
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Definition
tapping along the facial nerve induces contractions |
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Term
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Definition
carpal spasms produced by occlusion of the circulation to the forearm |
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