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pathogenicity
microbiology
49
Microbiology
Undergraduate 2
10/27/2015

Additional Microbiology Flashcards

 


 

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Term
Protein A on cell surface
Definition
Interferes with immune response and inhibits phagocytosis

Staphylococcus aureus, Staphylococcus epidermis
Term
Bound coagulase
Definition
Produces clot to hide bacteria

Staphylococcus aureus, Staphylococcus epidermis
Term
M Protein
Definition
Lyse white blood cells and affect phagocytosis

Streptococcus pyogenes
Term
Hyaluronic acid capsule
Definition
Coat that prevents host cells from recognizing pathogen

Streptococcus pyogenes
Term
Capsules
Definition
Hides pathogen

Streptococcus pneumonia, Staphylococcus aureus, Staphylococcus epidermis, Streptococcus agalactae
Term
Protein adhesions
Definition
Binds to lining of pharynx

Streptococcus pneumonia
Term
Phosphorylcholine
Definition
Secretes to cause phagocytosis

Streptococcus pneumonia
Term
Endospores
Definition
Allows for survival in harsh conditions

Clostridium sps. (All)
Bacillus sps. (All)
Term
Cord factor
Definition
Prevent neutrophils from engulfing endospore

Mycobacterium tuberculosis
Term
Cell free coagulase
Definition
Releases enzyme that clots blood

Staphylococcus aureus
Term
Hyaluronidase
Definition
Breaks down hyaluronic acid

Staphylococcus epidermis,
Staphylococcus aureus, Streptococcus pyogenes, Streptococcus agalactae,
Clostridium difficile
Term
Staphylokinase
Definition
Dissolves blood clot

Staphylococcus aureus, Staphylococcus epidermis
Term
Lipases
Definition
Digest and disolve lipids

Staphylococcus aureus, Staphylococcus epidermis
Term
B-lactamase
Definition
Breaks down penicillin

Staphylococcus aureus
Term
Streptokinase
Definition
Breaks down blood clot

Streptococcus pyogenes
Term
Deoxyribonucleases
Definition
Enzymes that breaks down your DNA

Streptococcus pyogenes, Streptococcus agalactae
Term
C5a peptidase
Definition
Peptide that decreases movement of WBC's

Streptococcus pyogenes
Term
Secretory IgA protease
Definition
Destroys IgA antibody

Streptococcus pneumonia
Term
Cytolytic toxins
Definition
Disrupt cell membrane of WBC'S so they can't phagocytize

Staphylococcus aureus and less frequently Staphylococcus epidermis
Term
Exfoliative toxins
Definition
Toxins that cause skin to fall off. Dissolves skin junctions

Staphylococcus aureus and less frequently Staphylococcus epidermis
Term
Toxic shock syndrome toxin
Definition
Releases toxins that cause toxic shock syndrome

Staphylococcus aureus and less frequently Staphylococcus epidermis
Term
Enterotoxins
Definition
Disrupts G.I. tract (food poisoning)

Staphylococcus aureus and less frequently Staphylococcus epidermis, Clostridium difficile, Clostridium perfringens, Clostridium botulinum, Clostridium tetani
Term
Pyrogenic toxins
Definition
Make things hot. Stimulates fever and rash

Streptococcus pyogenes
Term
Streptolysins
Definition
Lyse blood cells; deplete oxygen, WBC'S and platelets (clotting)

Streptococcus pyogenes
Term
Hemolysins
Definition
Lyse blood cells

Streptococcus agalactae
Term
Pneumolysin
Definition
Lyse cells

Streptococcus pneumonia
Term
Bacteriocins
Definition
Inhibit the growth of other bacteria

Enterococcus faecalis
Term
Anthrax toxins
Definition
Interferes with cellular respiration

Bacillus anthracis
Term
Histolytic toxins
Definition
Similar to cytolytic toxins, cause distruction of blood cells (RBC'S, WBC'S, and platelets)

Clostridium perfringens, Clostridium difficile, Clostridium botulinum, Clostridium tetani
Term
Neurotoxins
Definition
Destruction of nerve cells

Clostridium perfringens, Clostridium difficile, Clostridium botulinum, Clostridium tetani
Term
Botulism toxins
Definition
Deadliest toxin, prevents muscles from being able to contract. Produces 7 distinct toxins

Clostridium botulinum
Term
Tetanospasmin toxin (tetanus toxin)
Definition
Fatal neurotoxin; most associated with lockjaw

Clostridium tetani
Term
Diphtheria toxin
Definition
Causes cell death

Corynebacterium diphtheriae
Term
Polysaccharide capsule
Definition
Protects from phagocytosis

Neisseria gonorrhoeae, Klebsiella pneumonia, Haemophilus influenza, Pseudomondas aeruginosa, Francisella tularensis, Bacterioides fragilis, Prevotella sps.
Term
Fimbriae
Definition
Assists with attachment

Neisseria gonorrhoeae, Neisseria meningitides, Escherichia coli, Pseudomondas aeruginosa, Bacterioides fragilis
Term
Adhesin
Definition
Assists with attachment

Escherichia coli, Yersinia sps., Yersinia pestis, Pseudomondas aeruginosa, Prevotella sps.
Term
Urease
Definition
Breaks urea down into CO2 and ammonia, increases pH and can lead to kidney stones

Proteus mirabilis
Term
Exoenzyme S
Definition
Inhibits protein synthesis

Pseudomondas aeruginosa
Term
Protease
Definition
Protects cell from immune system

Neisseria gonorrhoeae, Prevotella sps.
Term
B-lactamase
Definition
Breaks down penicillin

Francisella tularensis
Term
Lipid A
Definition
Triggers fever, vasodilation, inflammation, and disseminated intravascular coagulation, portion of the cell wall in all gram negative, endotoxin, released when cell divides or dies

All gram negative bacteria
Term
Enterotoxins
Definition
Disrupts cells of gastrointestinal tract, leads to diarrhea, cramping, nausea, vomiting

Escherichia coli, Shigella sps.
Term
Shiga toxin
Definition
Stops protein synthesis and causes cell death

Shigella
Term
Pertussis toxin
Definition
Interferes with ciliated epithelial cell metabolism and results in an increase in mucous production

Bordetella pertussis
Term
Adenylate cyclase toxin
Definition
Triggers mucous production, inhibits leukocyte movement, phagocytosis

Bordetella pertussis
Term
Dermonecrotic toxin
Definition
Causes localized constriction and hemorrhage of blood vessels resulting in cell death and tissue destruction

Bordetella pertussis
Term
Exotoxin A
Definition
Inhibits protein synthesis

Pseudomondas aeruginosa
Term
Virulence plasmids
Definition
Allows virulence factors to be transmitted from one bacteria to another during conjugation

Escherichia coli, Yersinia sps,
Yersinia pestis
Term
Type 3 secretion system
Definition
Introduce proteins into host cell and inhibits phagocytosis, rearranges the cytoskeleton of eukaryotic cells, and induce apoptosis

Salmonella enterica (serotype Dublin and serotype typhi)
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